| Full name: BCL2 associated transcription factor 1 | Alias Symbol: KIAA0164|BTF | ||
| Type: protein-coding gene | Cytoband: 6q23.3 | ||
| Entrez ID: 9774 | HGNC ID: HGNC:16863 | Ensembl Gene: ENSG00000029363 | OMIM ID: 612588 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of BCLAF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BCLAF1 | 9774 | 201084_s_at | -0.1305 | 0.7382 | |
| GSE20347 | BCLAF1 | 9774 | 201084_s_at | -0.2741 | 0.0377 | |
| GSE23400 | BCLAF1 | 9774 | 201084_s_at | 0.0516 | 0.5029 | |
| GSE26886 | BCLAF1 | 9774 | 201084_s_at | -0.5052 | 0.0190 | |
| GSE29001 | BCLAF1 | 9774 | 201084_s_at | -0.0023 | 0.9901 | |
| GSE38129 | BCLAF1 | 9774 | 201084_s_at | -0.1340 | 0.2128 | |
| GSE45670 | BCLAF1 | 9774 | 201084_s_at | -0.4122 | 0.0001 | |
| GSE53622 | BCLAF1 | 9774 | 53629 | -0.1098 | 0.0050 | |
| GSE53624 | BCLAF1 | 9774 | 53629 | 0.1546 | 0.0000 | |
| GSE63941 | BCLAF1 | 9774 | 201084_s_at | -0.9775 | 0.0244 | |
| GSE77861 | BCLAF1 | 9774 | 201084_s_at | -0.2069 | 0.3845 | |
| GSE97050 | BCLAF1 | 9774 | A_23_P111343 | -0.0846 | 0.7255 | |
| SRP007169 | BCLAF1 | 9774 | RNAseq | 0.0451 | 0.8735 | |
| SRP008496 | BCLAF1 | 9774 | RNAseq | 0.1878 | 0.1901 | |
| SRP064894 | BCLAF1 | 9774 | RNAseq | -0.3270 | 0.1132 | |
| SRP133303 | BCLAF1 | 9774 | RNAseq | -0.0655 | 0.5692 | |
| SRP159526 | BCLAF1 | 9774 | RNAseq | -0.2913 | 0.2070 | |
| SRP193095 | BCLAF1 | 9774 | RNAseq | -0.4126 | 0.0000 | |
| SRP219564 | BCLAF1 | 9774 | RNAseq | -0.3408 | 0.1800 | |
| TCGA | BCLAF1 | 9774 | RNAseq | -0.0410 | 0.2968 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by BCLAF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BCLAF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BCLAF1 | 9774 | 2 | 5 | 23 | |
| GSE20123 | BCLAF1 | 9774 | 2 | 3 | 25 | |
| GSE43470 | BCLAF1 | 9774 | 5 | 0 | 38 | |
| GSE46452 | BCLAF1 | 9774 | 3 | 10 | 46 | |
| GSE47630 | BCLAF1 | 9774 | 9 | 4 | 27 | |
| GSE54993 | BCLAF1 | 9774 | 3 | 2 | 65 | |
| GSE54994 | BCLAF1 | 9774 | 9 | 7 | 37 | |
| GSE60625 | BCLAF1 | 9774 | 0 | 1 | 10 | |
| GSE74703 | BCLAF1 | 9774 | 4 | 0 | 32 | |
| GSE74704 | BCLAF1 | 9774 | 0 | 2 | 18 | |
| TCGA | BCLAF1 | 9774 | 12 | 17 | 67 |
Total number of gains: 49; Total number of losses: 51; Total Number of normals: 388.
Somatic mutations of BCLAF1:
Generating mutation plots.
Highly correlated genes for BCLAF1:
Showing top 20/627 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BCLAF1 | AKAP17A | 0.785424 | 3 | 0 | 3 |
| BCLAF1 | UBR3 | 0.740284 | 4 | 0 | 4 |
| BCLAF1 | SENP8 | 0.735045 | 3 | 0 | 3 |
| BCLAF1 | ZNF514 | 0.726568 | 3 | 0 | 3 |
| BCLAF1 | PAN3 | 0.724984 | 4 | 0 | 4 |
| BCLAF1 | TMEM181 | 0.723783 | 4 | 0 | 4 |
| BCLAF1 | UQCR11 | 0.720962 | 3 | 0 | 3 |
| BCLAF1 | SLC35D2 | 0.71816 | 3 | 0 | 3 |
| BCLAF1 | DIS3L | 0.715699 | 3 | 0 | 3 |
| BCLAF1 | GPBP1 | 0.71536 | 3 | 0 | 3 |
| BCLAF1 | ALDH6A1 | 0.715012 | 4 | 0 | 4 |
| BCLAF1 | CYTH2 | 0.71497 | 3 | 0 | 3 |
| BCLAF1 | PEX2 | 0.712305 | 3 | 0 | 3 |
| BCLAF1 | LSM14A | 0.710923 | 4 | 0 | 4 |
| BCLAF1 | ZNF805 | 0.709515 | 4 | 0 | 3 |
| BCLAF1 | C19orf18 | 0.708415 | 3 | 0 | 3 |
| BCLAF1 | ZNF583 | 0.699461 | 4 | 0 | 3 |
| BCLAF1 | ZNF227 | 0.698712 | 4 | 0 | 3 |
| BCLAF1 | EZH1 | 0.698389 | 5 | 0 | 4 |
| BCLAF1 | RBM20 | 0.695877 | 5 | 0 | 5 |
For details and further investigation, click here
