KDM4B

 

Full name: lysine demethylase 4B Alias Symbol: KIAA0876|TDRD14B
Type: protein-coding gene Cytoband: 19p13.3
Entrez ID: 23030 HGNC ID: HGNC:29136 Ensembl Gene: ENSG00000127663 OMIM ID: 609765
Drug and gene relationship at DGIdb

 

Expression of KDM4B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KDM4B 23030 212496_s_at -0.2972 0.5242
GSE20347 KDM4B 23030 212492_s_at -0.2342 0.1314
GSE23400 KDM4B 23030 212496_s_at -0.2593 0.0001
GSE26886 KDM4B 23030 212496_s_at 0.5270 0.0040
GSE29001 KDM4B 23030 212496_s_at -0.4757 0.2731
GSE38129 KDM4B 23030 212496_s_at -0.2127 0.0343
GSE45670 KDM4B 23030 212496_s_at -0.1012 0.5184
GSE53622 KDM4B 23030 79646 -0.6208 0.0000
GSE53624 KDM4B 23030 79646 -0.2901 0.0001
GSE63941 KDM4B 23030 212496_s_at -0.7898 0.1280
GSE77861 KDM4B 23030 212496_s_at -0.1473 0.5789
GSE97050 KDM4B 23030 A_33_P3319920 -0.4065 0.1313
SRP007169 KDM4B 23030 RNAseq -0.3500 0.3889
SRP008496 KDM4B 23030 RNAseq -0.4546 0.0771
SRP064894 KDM4B 23030 RNAseq -0.2104 0.1371
SRP133303 KDM4B 23030 RNAseq -0.1626 0.2103
SRP159526 KDM4B 23030 RNAseq -0.4248 0.0558
SRP193095 KDM4B 23030 RNAseq 0.1038 0.4856
SRP219564 KDM4B 23030 RNAseq -0.3714 0.2092
TCGA KDM4B 23030 RNAseq -0.0794 0.0960

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by KDM4B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of KDM4B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KDM4B 23030 5 3 22
GSE20123 KDM4B 23030 4 2 24
GSE43470 KDM4B 23030 1 8 34
GSE46452 KDM4B 23030 47 1 11
GSE47630 KDM4B 23030 5 7 28
GSE54993 KDM4B 23030 16 3 51
GSE54994 KDM4B 23030 6 16 31
GSE60625 KDM4B 23030 9 0 2
GSE74703 KDM4B 23030 1 5 30
GSE74704 KDM4B 23030 1 2 17
TCGA KDM4B 23030 11 18 67

Total number of gains: 106; Total number of losses: 65; Total Number of normals: 317.  


 

Somatic mutations of KDM4B:

 

Generating mutation plots.

 

Highly correlated genes for KDM4B:

 

Showing top 20/461 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KDM4BZNF5640.749674303
KDM4BLCOR0.744931303
KDM4BRBM40.74126303
KDM4BTXNL4A0.740776303
KDM4BEVI5L0.731293303
KDM4BDGCR20.72912505
KDM4BPAN30.72905303
KDM4BZNF4140.72778303
KDM4BEHMT20.722062303
KDM4BTTN0.718605303
KDM4BDYM0.718517303
KDM4BSCAMP40.717961303
KDM4BRPS160.716793303
KDM4BZNF440.713079303
KDM4BZNF7710.709896303
KDM4BLGI20.706544303
KDM4BARAF0.704906303
KDM4BSLIT30.704646303
KDM4BMED120.70312403
KDM4BSMG90.698619303

For details and further investigation, click here