| Full name: G protein-coupled receptor class C group 5 member B | Alias Symbol: RAIG-2 | ||
| Type: protein-coding gene | Cytoband: 16p12.3 | ||
| Entrez ID: 51704 | HGNC ID: HGNC:13308 | Ensembl Gene: ENSG00000167191 | OMIM ID: 605948 |
| Drug and gene relationship at DGIdb | |||
Expression of GPRC5B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPRC5B | 51704 | 203632_s_at | -1.3040 | 0.1664 | |
| GSE20347 | GPRC5B | 51704 | 203632_s_at | 0.3631 | 0.1709 | |
| GSE23400 | GPRC5B | 51704 | 203632_s_at | -0.0208 | 0.8664 | |
| GSE26886 | GPRC5B | 51704 | 203632_s_at | 1.0145 | 0.0583 | |
| GSE29001 | GPRC5B | 51704 | 203632_s_at | 0.4999 | 0.1422 | |
| GSE38129 | GPRC5B | 51704 | 203632_s_at | 0.1264 | 0.7069 | |
| GSE45670 | GPRC5B | 51704 | 203632_s_at | -0.7362 | 0.0770 | |
| GSE53622 | GPRC5B | 51704 | 69317 | -0.3544 | 0.0158 | |
| GSE53624 | GPRC5B | 51704 | 69317 | 0.0720 | 0.6522 | |
| GSE63941 | GPRC5B | 51704 | 203632_s_at | -2.4063 | 0.0443 | |
| GSE77861 | GPRC5B | 51704 | 228313_at | -0.1990 | 0.2179 | |
| GSE97050 | GPRC5B | 51704 | A_23_P324327 | -0.2396 | 0.3094 | |
| SRP007169 | GPRC5B | 51704 | RNAseq | 2.7388 | 0.0000 | |
| SRP008496 | GPRC5B | 51704 | RNAseq | 2.5271 | 0.0000 | |
| SRP064894 | GPRC5B | 51704 | RNAseq | -0.2463 | 0.4593 | |
| SRP133303 | GPRC5B | 51704 | RNAseq | -0.4148 | 0.0739 | |
| SRP159526 | GPRC5B | 51704 | RNAseq | 1.1238 | 0.0750 | |
| SRP193095 | GPRC5B | 51704 | RNAseq | -0.2857 | 0.5132 | |
| SRP219564 | GPRC5B | 51704 | RNAseq | -0.0635 | 0.9205 | |
| TCGA | GPRC5B | 51704 | RNAseq | -0.7782 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by GPRC5B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPRC5B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPRC5B | 51704 | 6 | 3 | 21 | |
| GSE20123 | GPRC5B | 51704 | 6 | 2 | 22 | |
| GSE43470 | GPRC5B | 51704 | 3 | 3 | 37 | |
| GSE46452 | GPRC5B | 51704 | 38 | 1 | 20 | |
| GSE47630 | GPRC5B | 51704 | 11 | 6 | 23 | |
| GSE54993 | GPRC5B | 51704 | 3 | 5 | 62 | |
| GSE54994 | GPRC5B | 51704 | 3 | 10 | 40 | |
| GSE60625 | GPRC5B | 51704 | 4 | 0 | 7 | |
| GSE74703 | GPRC5B | 51704 | 3 | 2 | 31 | |
| GSE74704 | GPRC5B | 51704 | 3 | 1 | 16 | |
| TCGA | GPRC5B | 51704 | 19 | 13 | 64 |
Total number of gains: 99; Total number of losses: 46; Total Number of normals: 343.
Somatic mutations of GPRC5B:
Generating mutation plots.
Highly correlated genes for GPRC5B:
Showing top 20/571 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPRC5B | RAB40AL | 0.757941 | 3 | 0 | 3 |
| GPRC5B | ZBED1 | 0.756577 | 3 | 0 | 3 |
| GPRC5B | CUL4B | 0.751474 | 3 | 0 | 3 |
| GPRC5B | GNE | 0.745775 | 3 | 0 | 3 |
| GPRC5B | INSRR | 0.733243 | 3 | 0 | 3 |
| GPRC5B | PAN3 | 0.732766 | 3 | 0 | 3 |
| GPRC5B | MIER1 | 0.72863 | 3 | 0 | 3 |
| GPRC5B | SNX25 | 0.719183 | 4 | 0 | 4 |
| GPRC5B | FAM122C | 0.717333 | 3 | 0 | 3 |
| GPRC5B | CHADL | 0.716287 | 3 | 0 | 3 |
| GPRC5B | A1BG | 0.706759 | 3 | 0 | 3 |
| GPRC5B | SNX3 | 0.705907 | 3 | 0 | 3 |
| GPRC5B | TMEM106B | 0.704658 | 4 | 0 | 4 |
| GPRC5B | FIS1 | 0.702455 | 4 | 0 | 3 |
| GPRC5B | NLGN4Y | 0.702438 | 4 | 0 | 3 |
| GPRC5B | TYW3 | 0.700514 | 3 | 0 | 3 |
| GPRC5B | VPS28 | 0.696761 | 3 | 0 | 3 |
| GPRC5B | RHOJ | 0.695769 | 4 | 0 | 3 |
| GPRC5B | OR7E24 | 0.695563 | 3 | 0 | 3 |
| GPRC5B | ZNF407 | 0.694111 | 3 | 0 | 3 |
For details and further investigation, click here
