| Full name: mitochondrial ribosomal protein L20 | Alias Symbol: FLJ10024 | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 55052 | HGNC ID: HGNC:14478 | Ensembl Gene: ENSG00000242485 | OMIM ID: 611833 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MRPL20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL20 | 55052 | 220526_s_at | -0.0344 | 0.9657 | |
| GSE20347 | MRPL20 | 55052 | 220526_s_at | 0.0565 | 0.6454 | |
| GSE23400 | MRPL20 | 55052 | 220526_s_at | 0.0350 | 0.6119 | |
| GSE26886 | MRPL20 | 55052 | 220526_s_at | -0.0149 | 0.9480 | |
| GSE29001 | MRPL20 | 55052 | 220526_s_at | 0.0491 | 0.8016 | |
| GSE38129 | MRPL20 | 55052 | 220526_s_at | 0.1048 | 0.2779 | |
| GSE45670 | MRPL20 | 55052 | 220526_s_at | 0.1187 | 0.3641 | |
| GSE53622 | MRPL20 | 55052 | 46382 | -0.2057 | 0.0001 | |
| GSE53624 | MRPL20 | 55052 | 46382 | 0.0549 | 0.2851 | |
| GSE63941 | MRPL20 | 55052 | 220526_s_at | -0.3120 | 0.3972 | |
| GSE77861 | MRPL20 | 55052 | 220526_s_at | -0.2325 | 0.1682 | |
| GSE97050 | MRPL20 | 55052 | A_24_P8768 | -0.1465 | 0.5662 | |
| SRP007169 | MRPL20 | 55052 | RNAseq | -0.9108 | 0.0072 | |
| SRP008496 | MRPL20 | 55052 | RNAseq | -0.8888 | 0.0000 | |
| SRP064894 | MRPL20 | 55052 | RNAseq | 0.3103 | 0.2853 | |
| SRP133303 | MRPL20 | 55052 | RNAseq | 0.1128 | 0.4322 | |
| SRP159526 | MRPL20 | 55052 | RNAseq | -0.1467 | 0.5746 | |
| SRP193095 | MRPL20 | 55052 | RNAseq | -0.3430 | 0.0117 | |
| SRP219564 | MRPL20 | 55052 | RNAseq | -0.3222 | 0.2580 | |
| TCGA | MRPL20 | 55052 | RNAseq | 0.0222 | 0.6727 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPL20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL20 | 55052 | 3 | 7 | 20 | |
| GSE20123 | MRPL20 | 55052 | 3 | 6 | 21 | |
| GSE43470 | MRPL20 | 55052 | 3 | 5 | 35 | |
| GSE46452 | MRPL20 | 55052 | 7 | 1 | 51 | |
| GSE47630 | MRPL20 | 55052 | 8 | 4 | 28 | |
| GSE54993 | MRPL20 | 55052 | 2 | 2 | 66 | |
| GSE54994 | MRPL20 | 55052 | 15 | 2 | 36 | |
| GSE60625 | MRPL20 | 55052 | 0 | 0 | 11 | |
| GSE74703 | MRPL20 | 55052 | 3 | 3 | 30 | |
| GSE74704 | MRPL20 | 55052 | 3 | 0 | 17 | |
| TCGA | MRPL20 | 55052 | 14 | 20 | 62 |
Total number of gains: 61; Total number of losses: 50; Total Number of normals: 377.
Somatic mutations of MRPL20:
Generating mutation plots.
Highly correlated genes for MRPL20:
Showing top 20/292 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL20 | FBXW8 | 0.788006 | 3 | 0 | 3 |
| MRPL20 | ZNF304 | 0.787739 | 3 | 0 | 3 |
| MRPL20 | RBBP6 | 0.785026 | 3 | 0 | 3 |
| MRPL20 | VPS26A | 0.783652 | 3 | 0 | 3 |
| MRPL20 | RBM4 | 0.780899 | 3 | 0 | 3 |
| MRPL20 | UBA52 | 0.774672 | 3 | 0 | 3 |
| MRPL20 | LPIN2 | 0.747845 | 3 | 0 | 3 |
| MRPL20 | PAN3 | 0.747553 | 3 | 0 | 3 |
| MRPL20 | ZNF616 | 0.740288 | 3 | 0 | 3 |
| MRPL20 | ARF6 | 0.734988 | 3 | 0 | 3 |
| MRPL20 | ACP6 | 0.733917 | 3 | 0 | 3 |
| MRPL20 | FBXO33 | 0.717256 | 3 | 0 | 3 |
| MRPL20 | PEMT | 0.715313 | 3 | 0 | 3 |
| MRPL20 | C10orf88 | 0.712758 | 3 | 0 | 3 |
| MRPL20 | KIF24 | 0.711968 | 3 | 0 | 3 |
| MRPL20 | HSPA2 | 0.711693 | 3 | 0 | 3 |
| MRPL20 | MRPL16 | 0.710228 | 3 | 0 | 3 |
| MRPL20 | ZNF17 | 0.704367 | 3 | 0 | 3 |
| MRPL20 | STK40 | 0.703234 | 3 | 0 | 3 |
| MRPL20 | OS9 | 0.700978 | 3 | 0 | 3 |
For details and further investigation, click here
