| Full name: phosphate cytidylyltransferase 2, ethanolamine | Alias Symbol: ET | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 5833 | HGNC ID: HGNC:8756 | Ensembl Gene: ENSG00000185813 | OMIM ID: 602679 |
| Drug and gene relationship at DGIdb | |||
Expression of PCYT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCYT2 | 5833 | 209577_at | 0.5301 | 0.2886 | |
| GSE20347 | PCYT2 | 5833 | 209577_at | -0.2145 | 0.0849 | |
| GSE23400 | PCYT2 | 5833 | 209577_at | -0.1282 | 0.0169 | |
| GSE26886 | PCYT2 | 5833 | 209577_at | -0.3407 | 0.0665 | |
| GSE29001 | PCYT2 | 5833 | 209577_at | -0.0875 | 0.6041 | |
| GSE38129 | PCYT2 | 5833 | 209577_at | -0.1642 | 0.0872 | |
| GSE45670 | PCYT2 | 5833 | 209577_at | 0.0492 | 0.7497 | |
| GSE53622 | PCYT2 | 5833 | 14187 | 0.1073 | 0.0294 | |
| GSE53624 | PCYT2 | 5833 | 14187 | -0.0080 | 0.9140 | |
| GSE63941 | PCYT2 | 5833 | 209577_at | -0.3543 | 0.3092 | |
| GSE77861 | PCYT2 | 5833 | 209577_at | -0.2748 | 0.3282 | |
| GSE97050 | PCYT2 | 5833 | A_24_P404245 | 0.3847 | 0.2082 | |
| SRP007169 | PCYT2 | 5833 | RNAseq | -0.1339 | 0.7587 | |
| SRP008496 | PCYT2 | 5833 | RNAseq | -0.3864 | 0.1565 | |
| SRP064894 | PCYT2 | 5833 | RNAseq | 0.2050 | 0.3894 | |
| SRP133303 | PCYT2 | 5833 | RNAseq | 0.0610 | 0.8121 | |
| SRP159526 | PCYT2 | 5833 | RNAseq | 0.3636 | 0.0421 | |
| SRP193095 | PCYT2 | 5833 | RNAseq | -0.4321 | 0.0086 | |
| SRP219564 | PCYT2 | 5833 | RNAseq | -0.2899 | 0.4510 | |
| TCGA | PCYT2 | 5833 | RNAseq | -0.0948 | 0.1258 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PCYT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCYT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCYT2 | 5833 | 4 | 4 | 22 | |
| GSE20123 | PCYT2 | 5833 | 4 | 4 | 22 | |
| GSE43470 | PCYT2 | 5833 | 3 | 5 | 35 | |
| GSE46452 | PCYT2 | 5833 | 34 | 0 | 25 | |
| GSE47630 | PCYT2 | 5833 | 9 | 2 | 29 | |
| GSE54993 | PCYT2 | 5833 | 2 | 5 | 63 | |
| GSE54994 | PCYT2 | 5833 | 10 | 6 | 37 | |
| GSE60625 | PCYT2 | 5833 | 6 | 0 | 5 | |
| GSE74703 | PCYT2 | 5833 | 3 | 3 | 30 | |
| GSE74704 | PCYT2 | 5833 | 4 | 3 | 13 | |
| TCGA | PCYT2 | 5833 | 25 | 12 | 59 |
Total number of gains: 104; Total number of losses: 44; Total Number of normals: 340.
Somatic mutations of PCYT2:
Generating mutation plots.
Highly correlated genes for PCYT2:
Showing top 20/140 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCYT2 | ADAM21 | 0.777504 | 3 | 0 | 3 |
| PCYT2 | MANEAL | 0.728017 | 3 | 0 | 3 |
| PCYT2 | ZSWIM3 | 0.709866 | 4 | 0 | 4 |
| PCYT2 | CLCN6 | 0.690087 | 3 | 0 | 3 |
| PCYT2 | SYT2 | 0.687841 | 3 | 0 | 3 |
| PCYT2 | ABHD11 | 0.685993 | 4 | 0 | 3 |
| PCYT2 | RPGRIP1L | 0.677793 | 3 | 0 | 3 |
| PCYT2 | CABP1 | 0.677343 | 3 | 0 | 3 |
| PCYT2 | KCP | 0.676919 | 3 | 0 | 3 |
| PCYT2 | TMEM102 | 0.672743 | 3 | 0 | 3 |
| PCYT2 | GPC2 | 0.671942 | 3 | 0 | 3 |
| PCYT2 | BRF1 | 0.666998 | 3 | 0 | 3 |
| PCYT2 | SHISA8 | 0.665716 | 3 | 0 | 3 |
| PCYT2 | TOR2A | 0.665688 | 3 | 0 | 3 |
| PCYT2 | SLC22A25 | 0.663046 | 3 | 0 | 3 |
| PCYT2 | LAT2 | 0.660916 | 3 | 0 | 3 |
| PCYT2 | DRGX | 0.657106 | 3 | 0 | 3 |
| PCYT2 | C20orf144 | 0.652565 | 3 | 0 | 3 |
| PCYT2 | ZNF138 | 0.647735 | 3 | 0 | 3 |
| PCYT2 | ASGR2 | 0.647193 | 3 | 0 | 3 |
For details and further investigation, click here
