| Full name: RPGRIP1 like | Alias Symbol: KIAA1005|CORS3|JBTS7|MKS5|NPHP8|FTM|PPP1R134 | ||
| Type: protein-coding gene | Cytoband: 16q12.2 | ||
| Entrez ID: 23322 | HGNC ID: HGNC:29168 | Ensembl Gene: ENSG00000103494 | OMIM ID: 610937 |
| Drug and gene relationship at DGIdb | |||
Expression of RPGRIP1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPGRIP1L | 23322 | 213959_s_at | 0.6128 | 0.3421 | |
| GSE20347 | RPGRIP1L | 23322 | 213959_s_at | 0.4549 | 0.0063 | |
| GSE23400 | RPGRIP1L | 23322 | 213959_s_at | 0.1339 | 0.0000 | |
| GSE26886 | RPGRIP1L | 23322 | 213959_s_at | 0.4890 | 0.0407 | |
| GSE29001 | RPGRIP1L | 23322 | 213959_s_at | 0.4445 | 0.1721 | |
| GSE38129 | RPGRIP1L | 23322 | 213959_s_at | 0.7486 | 0.0000 | |
| GSE45670 | RPGRIP1L | 23322 | 213959_s_at | 0.5023 | 0.0576 | |
| GSE53622 | RPGRIP1L | 23322 | 89445 | 0.0878 | 0.4208 | |
| GSE53624 | RPGRIP1L | 23322 | 89445 | 0.2857 | 0.0054 | |
| GSE63941 | RPGRIP1L | 23322 | 213959_s_at | -0.7280 | 0.2542 | |
| GSE77861 | RPGRIP1L | 23322 | 241028_at | -0.0961 | 0.3974 | |
| SRP007169 | RPGRIP1L | 23322 | RNAseq | 1.0408 | 0.1150 | |
| SRP008496 | RPGRIP1L | 23322 | RNAseq | 1.4878 | 0.0001 | |
| SRP064894 | RPGRIP1L | 23322 | RNAseq | 0.6632 | 0.0011 | |
| SRP133303 | RPGRIP1L | 23322 | RNAseq | 0.7012 | 0.0000 | |
| SRP159526 | RPGRIP1L | 23322 | RNAseq | 0.7293 | 0.0908 | |
| SRP193095 | RPGRIP1L | 23322 | RNAseq | 0.3754 | 0.0008 | |
| SRP219564 | RPGRIP1L | 23322 | RNAseq | 0.3074 | 0.4501 | |
| TCGA | RPGRIP1L | 23322 | RNAseq | 0.4078 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RPGRIP1L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPGRIP1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPGRIP1L | 23322 | 3 | 0 | 27 | |
| GSE20123 | RPGRIP1L | 23322 | 3 | 0 | 27 | |
| GSE43470 | RPGRIP1L | 23322 | 2 | 7 | 34 | |
| GSE46452 | RPGRIP1L | 23322 | 38 | 1 | 20 | |
| GSE47630 | RPGRIP1L | 23322 | 11 | 7 | 22 | |
| GSE54993 | RPGRIP1L | 23322 | 2 | 5 | 63 | |
| GSE54994 | RPGRIP1L | 23322 | 7 | 10 | 36 | |
| GSE60625 | RPGRIP1L | 23322 | 4 | 0 | 7 | |
| GSE74703 | RPGRIP1L | 23322 | 2 | 4 | 30 | |
| GSE74704 | RPGRIP1L | 23322 | 3 | 0 | 17 | |
| TCGA | RPGRIP1L | 23322 | 26 | 11 | 59 |
Total number of gains: 101; Total number of losses: 45; Total Number of normals: 342.
Somatic mutations of RPGRIP1L:
Generating mutation plots.
Highly correlated genes for RPGRIP1L:
Showing top 20/183 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPGRIP1L | EMC1 | 0.735125 | 3 | 0 | 3 |
| RPGRIP1L | SYCN | 0.721601 | 3 | 0 | 3 |
| RPGRIP1L | SLC22A25 | 0.680766 | 3 | 0 | 3 |
| RPGRIP1L | PCYT2 | 0.677793 | 3 | 0 | 3 |
| RPGRIP1L | LYZL1 | 0.674485 | 3 | 0 | 3 |
| RPGRIP1L | RPRML | 0.662218 | 3 | 0 | 3 |
| RPGRIP1L | TNNI1 | 0.659398 | 3 | 0 | 3 |
| RPGRIP1L | CC2D1B | 0.659227 | 3 | 0 | 3 |
| RPGRIP1L | FZD2 | 0.65369 | 4 | 0 | 3 |
| RPGRIP1L | BFSP2-AS1 | 0.653194 | 3 | 0 | 3 |
| RPGRIP1L | LRRC71 | 0.649538 | 3 | 0 | 3 |
| RPGRIP1L | FNDC9 | 0.64754 | 3 | 0 | 3 |
| RPGRIP1L | SLC18A3 | 0.640178 | 3 | 0 | 3 |
| RPGRIP1L | TCTE1 | 0.638666 | 3 | 0 | 3 |
| RPGRIP1L | KIF9 | 0.637549 | 3 | 0 | 3 |
| RPGRIP1L | ATCAY | 0.635851 | 3 | 0 | 3 |
| RPGRIP1L | USP1 | 0.634307 | 5 | 0 | 4 |
| RPGRIP1L | CST4 | 0.62656 | 4 | 0 | 3 |
| RPGRIP1L | ZZZ3 | 0.625515 | 5 | 0 | 3 |
| RPGRIP1L | LINC00475 | 0.625085 | 3 | 0 | 3 |
For details and further investigation, click here
