| Full name: torsin family 2 member A | Alias Symbol: FLJ14771|TORP1 | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 27433 | HGNC ID: HGNC:11996 | Ensembl Gene: ENSG00000160404 | OMIM ID: 608052 |
| Drug and gene relationship at DGIdb | |||
Expression of TOR2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TOR2A | 27433 | 227972_at | 0.2682 | 0.5183 | |
| GSE26886 | TOR2A | 27433 | 227972_at | 0.2634 | 0.0890 | |
| GSE45670 | TOR2A | 27433 | 227972_at | 0.4026 | 0.0000 | |
| GSE53622 | TOR2A | 27433 | 14003 | 0.0175 | 0.8128 | |
| GSE53624 | TOR2A | 27433 | 14003 | 0.0204 | 0.7670 | |
| GSE63941 | TOR2A | 27433 | 227972_at | 1.0883 | 0.0144 | |
| GSE77861 | TOR2A | 27433 | 227972_at | 0.0155 | 0.9222 | |
| GSE97050 | TOR2A | 27433 | A_33_P3275835 | 0.0223 | 0.9171 | |
| SRP007169 | TOR2A | 27433 | RNAseq | -0.0141 | 0.9759 | |
| SRP008496 | TOR2A | 27433 | RNAseq | -0.0101 | 0.9780 | |
| SRP064894 | TOR2A | 27433 | RNAseq | 0.9321 | 0.0032 | |
| SRP133303 | TOR2A | 27433 | RNAseq | 0.7708 | 0.0018 | |
| SRP159526 | TOR2A | 27433 | RNAseq | 0.1750 | 0.4004 | |
| SRP193095 | TOR2A | 27433 | RNAseq | 0.0855 | 0.5560 | |
| SRP219564 | TOR2A | 27433 | RNAseq | 0.8456 | 0.1206 | |
| TCGA | TOR2A | 27433 | RNAseq | 0.1363 | 0.0580 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TOR2A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TOR2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TOR2A | 27433 | 6 | 9 | 15 | |
| GSE20123 | TOR2A | 27433 | 6 | 9 | 15 | |
| GSE43470 | TOR2A | 27433 | 5 | 6 | 32 | |
| GSE46452 | TOR2A | 27433 | 6 | 13 | 40 | |
| GSE47630 | TOR2A | 27433 | 4 | 15 | 21 | |
| GSE54993 | TOR2A | 27433 | 3 | 3 | 64 | |
| GSE54994 | TOR2A | 27433 | 11 | 8 | 34 | |
| GSE60625 | TOR2A | 27433 | 0 | 0 | 11 | |
| GSE74703 | TOR2A | 27433 | 5 | 4 | 27 | |
| GSE74704 | TOR2A | 27433 | 3 | 7 | 10 | |
| TCGA | TOR2A | 27433 | 27 | 25 | 44 |
Total number of gains: 76; Total number of losses: 99; Total Number of normals: 313.
Somatic mutations of TOR2A:
Generating mutation plots.
Highly correlated genes for TOR2A:
Showing top 20/443 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TOR2A | KIRREL2 | 0.875093 | 3 | 0 | 3 |
| TOR2A | SALL3 | 0.857164 | 3 | 0 | 3 |
| TOR2A | YY2 | 0.836241 | 3 | 0 | 3 |
| TOR2A | OR2H1 | 0.833924 | 3 | 0 | 3 |
| TOR2A | ZNF329 | 0.831409 | 3 | 0 | 3 |
| TOR2A | DCDC1 | 0.827538 | 3 | 0 | 3 |
| TOR2A | SLC22A7 | 0.827354 | 3 | 0 | 3 |
| TOR2A | BTNL2 | 0.826188 | 3 | 0 | 3 |
| TOR2A | C9orf153 | 0.817444 | 3 | 0 | 3 |
| TOR2A | STRC | 0.816265 | 3 | 0 | 3 |
| TOR2A | WDR87 | 0.813625 | 3 | 0 | 3 |
| TOR2A | CELF5 | 0.810987 | 3 | 0 | 3 |
| TOR2A | C1QL2 | 0.806192 | 3 | 0 | 3 |
| TOR2A | SPACA3 | 0.801875 | 4 | 0 | 4 |
| TOR2A | UFSP1 | 0.801398 | 4 | 0 | 4 |
| TOR2A | SERPINA10 | 0.799728 | 3 | 0 | 3 |
| TOR2A | PRSS38 | 0.799292 | 3 | 0 | 3 |
| TOR2A | DEFB121 | 0.79814 | 3 | 0 | 3 |
| TOR2A | TMEM179 | 0.79626 | 3 | 0 | 3 |
| TOR2A | MYOD1 | 0.794691 | 3 | 0 | 3 |
For details and further investigation, click here
