| Full name: abhydrolase domain containing 11 | Alias Symbol: PP1226 | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 83451 | HGNC ID: HGNC:16407 | Ensembl Gene: ENSG00000106077 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ABHD11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABHD11 | 83451 | 221927_s_at | 0.3210 | 0.5866 | |
| GSE20347 | ABHD11 | 83451 | 221927_s_at | 0.2713 | 0.1649 | |
| GSE23400 | ABHD11 | 83451 | 221927_s_at | 0.0634 | 0.4849 | |
| GSE26886 | ABHD11 | 83451 | 221927_s_at | 0.2205 | 0.2480 | |
| GSE29001 | ABHD11 | 83451 | 221927_s_at | -0.2752 | 0.2010 | |
| GSE38129 | ABHD11 | 83451 | 221927_s_at | 0.3325 | 0.0308 | |
| GSE45670 | ABHD11 | 83451 | 221927_s_at | 0.0798 | 0.7727 | |
| GSE53622 | ABHD11 | 83451 | 28618 | 0.2362 | 0.0026 | |
| GSE53624 | ABHD11 | 83451 | 28618 | 0.1750 | 0.0026 | |
| GSE63941 | ABHD11 | 83451 | 221927_s_at | 1.3764 | 0.0180 | |
| GSE77861 | ABHD11 | 83451 | 221927_s_at | 0.2968 | 0.1084 | |
| GSE97050 | ABHD11 | 83451 | A_23_P315933 | 0.2234 | 0.3258 | |
| SRP007169 | ABHD11 | 83451 | RNAseq | -0.1202 | 0.7532 | |
| SRP064894 | ABHD11 | 83451 | RNAseq | -0.0202 | 0.9410 | |
| SRP133303 | ABHD11 | 83451 | RNAseq | 0.0216 | 0.9178 | |
| SRP159526 | ABHD11 | 83451 | RNAseq | 0.2677 | 0.3193 | |
| SRP193095 | ABHD11 | 83451 | RNAseq | 0.3721 | 0.0232 | |
| SRP219564 | ABHD11 | 83451 | RNAseq | 0.2650 | 0.5482 | |
| TCGA | ABHD11 | 83451 | RNAseq | 0.1882 | 0.0365 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ABHD11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABHD11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABHD11 | 83451 | 14 | 1 | 15 | |
| GSE20123 | ABHD11 | 83451 | 14 | 1 | 15 | |
| GSE43470 | ABHD11 | 83451 | 3 | 2 | 38 | |
| GSE46452 | ABHD11 | 83451 | 12 | 0 | 47 | |
| GSE47630 | ABHD11 | 83451 | 7 | 2 | 31 | |
| GSE54993 | ABHD11 | 83451 | 2 | 7 | 61 | |
| GSE54994 | ABHD11 | 83451 | 14 | 3 | 36 | |
| GSE60625 | ABHD11 | 83451 | 0 | 0 | 11 | |
| GSE74703 | ABHD11 | 83451 | 3 | 1 | 32 | |
| GSE74704 | ABHD11 | 83451 | 8 | 1 | 11 | |
| TCGA | ABHD11 | 83451 | 45 | 7 | 44 |
Total number of gains: 122; Total number of losses: 25; Total Number of normals: 341.
Somatic mutations of ABHD11:
Generating mutation plots.
Highly correlated genes for ABHD11:
Showing top 20/118 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABHD11 | WDR83 | 0.789317 | 3 | 0 | 3 |
| ABHD11 | RDH13 | 0.787384 | 3 | 0 | 3 |
| ABHD11 | PRPF31 | 0.774516 | 3 | 0 | 3 |
| ABHD11 | ALKBH2 | 0.77051 | 3 | 0 | 3 |
| ABHD11 | BRD1 | 0.733037 | 3 | 0 | 3 |
| ABHD11 | CAPN10 | 0.726736 | 3 | 0 | 3 |
| ABHD11 | LRRC45 | 0.725862 | 3 | 0 | 3 |
| ABHD11 | POLL | 0.712327 | 3 | 0 | 3 |
| ABHD11 | C19orf53 | 0.706497 | 4 | 0 | 3 |
| ABHD11 | CDC34 | 0.692981 | 4 | 0 | 3 |
| ABHD11 | UBXN11 | 0.691416 | 3 | 0 | 3 |
| ABHD11 | PCYT2 | 0.685993 | 4 | 0 | 3 |
| ABHD11 | PYGO2 | 0.683083 | 4 | 0 | 4 |
| ABHD11 | TRIM41 | 0.681978 | 3 | 0 | 3 |
| ABHD11 | BAX | 0.676226 | 3 | 0 | 3 |
| ABHD11 | NR2C2AP | 0.675681 | 3 | 0 | 3 |
| ABHD11 | TP53BP1 | 0.672974 | 3 | 0 | 3 |
| ABHD11 | ZDHHC23 | 0.664071 | 4 | 0 | 4 |
| ABHD11 | AGPAT2 | 0.66335 | 3 | 0 | 3 |
| ABHD11 | WDR34 | 0.662956 | 3 | 0 | 3 |
For details and further investigation, click here
