| Full name: mannosidase endo-alpha like | Alias Symbol: FLJ31434 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 149175 | HGNC ID: HGNC:26452 | Ensembl Gene: ENSG00000185090 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MANEAL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MANEAL | 149175 | 226132_s_at | 0.4096 | 0.7638 | |
| GSE26886 | MANEAL | 149175 | 226132_s_at | -0.5702 | 0.0190 | |
| GSE45670 | MANEAL | 149175 | 226132_s_at | 0.0720 | 0.8618 | |
| GSE53622 | MANEAL | 149175 | 73198 | -0.1968 | 0.0471 | |
| GSE53624 | MANEAL | 149175 | 73198 | 0.0673 | 0.3319 | |
| GSE63941 | MANEAL | 149175 | 226132_s_at | 1.2649 | 0.1881 | |
| GSE97050 | MANEAL | 149175 | A_33_P3369505 | 0.5086 | 0.2001 | |
| SRP007169 | MANEAL | 149175 | RNAseq | -2.6307 | 0.0000 | |
| SRP064894 | MANEAL | 149175 | RNAseq | -0.0901 | 0.8077 | |
| SRP133303 | MANEAL | 149175 | RNAseq | -0.2474 | 0.5013 | |
| SRP159526 | MANEAL | 149175 | RNAseq | -0.1781 | 0.8047 | |
| SRP193095 | MANEAL | 149175 | RNAseq | -0.3699 | 0.1710 | |
| SRP219564 | MANEAL | 149175 | RNAseq | 1.0438 | 0.1540 | |
| TCGA | MANEAL | 149175 | RNAseq | -0.0327 | 0.8839 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MANEAL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MANEAL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MANEAL | 149175 | 2 | 4 | 24 | |
| GSE20123 | MANEAL | 149175 | 2 | 3 | 25 | |
| GSE43470 | MANEAL | 149175 | 7 | 3 | 33 | |
| GSE46452 | MANEAL | 149175 | 4 | 1 | 54 | |
| GSE47630 | MANEAL | 149175 | 8 | 3 | 29 | |
| GSE54993 | MANEAL | 149175 | 1 | 1 | 68 | |
| GSE54994 | MANEAL | 149175 | 12 | 2 | 39 | |
| GSE60625 | MANEAL | 149175 | 0 | 0 | 11 | |
| GSE74703 | MANEAL | 149175 | 6 | 2 | 28 | |
| GSE74704 | MANEAL | 149175 | 1 | 0 | 19 | |
| TCGA | MANEAL | 149175 | 12 | 16 | 68 |
Total number of gains: 55; Total number of losses: 35; Total Number of normals: 398.
Somatic mutations of MANEAL:
Generating mutation plots.
Highly correlated genes for MANEAL:
Showing top 20/36 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MANEAL | PCYT2 | 0.728017 | 3 | 0 | 3 |
| MANEAL | HPDL | 0.694766 | 3 | 0 | 3 |
| MANEAL | ALKBH2 | 0.689159 | 3 | 0 | 3 |
| MANEAL | ZSWIM3 | 0.683504 | 3 | 0 | 3 |
| MANEAL | CC2D1B | 0.682106 | 3 | 0 | 3 |
| MANEAL | TSC2 | 0.682066 | 3 | 0 | 3 |
| MANEAL | CARD8 | 0.678277 | 3 | 0 | 3 |
| MANEAL | PRDM13 | 0.672148 | 3 | 0 | 3 |
| MANEAL | PAFAH1B3 | 0.649617 | 4 | 0 | 3 |
| MANEAL | ZNF749 | 0.621697 | 3 | 0 | 3 |
| MANEAL | ASPHD2 | 0.613409 | 3 | 0 | 3 |
| MANEAL | PWWP2B | 0.612988 | 3 | 0 | 3 |
| MANEAL | ZNF329 | 0.611026 | 3 | 0 | 3 |
| MANEAL | ZNF48 | 0.609463 | 3 | 0 | 3 |
| MANEAL | RPL30 | 0.605313 | 3 | 0 | 3 |
| MANEAL | COPS7B | 0.603894 | 3 | 0 | 3 |
| MANEAL | FGF22 | 0.59959 | 3 | 0 | 3 |
| MANEAL | HNRNPK | 0.599476 | 3 | 0 | 3 |
| MANEAL | NKX2-3 | 0.596056 | 3 | 0 | 3 |
| MANEAL | ABCD3 | 0.589878 | 3 | 0 | 3 |
For details and further investigation, click here
