| Full name: synaptotagmin 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 127833 | HGNC ID: HGNC:11510 | Ensembl Gene: ENSG00000143858 | OMIM ID: 600104 |
| Drug and gene relationship at DGIdb | |||
Expression of SYT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYT2 | 127833 | 214903_at | -0.0873 | 0.7449 | |
| GSE20347 | SYT2 | 127833 | 214903_at | -0.0799 | 0.4958 | |
| GSE23400 | SYT2 | 127833 | 214903_at | -0.0859 | 0.0216 | |
| GSE26886 | SYT2 | 127833 | 214903_at | -0.0413 | 0.8324 | |
| GSE29001 | SYT2 | 127833 | 214903_at | -0.3228 | 0.1030 | |
| GSE38129 | SYT2 | 127833 | 214903_at | -0.2375 | 0.0158 | |
| GSE45670 | SYT2 | 127833 | 214903_at | 0.2740 | 0.0490 | |
| GSE53622 | SYT2 | 127833 | 34764 | -0.1275 | 0.0652 | |
| GSE53624 | SYT2 | 127833 | 34764 | -0.0075 | 0.9312 | |
| GSE63941 | SYT2 | 127833 | 214903_at | 0.2291 | 0.3208 | |
| GSE77861 | SYT2 | 127833 | 214903_at | -0.1231 | 0.4498 | |
| GSE97050 | SYT2 | 127833 | A_23_P104098 | -0.0027 | 0.9915 | |
| SRP133303 | SYT2 | 127833 | RNAseq | -0.5349 | 0.0381 | |
| SRP159526 | SYT2 | 127833 | RNAseq | 0.7419 | 0.1855 | |
| SRP193095 | SYT2 | 127833 | RNAseq | 0.2310 | 0.2050 | |
| SRP219564 | SYT2 | 127833 | RNAseq | 0.4129 | 0.4426 | |
| TCGA | SYT2 | 127833 | RNAseq | -0.4805 | 0.0674 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SYT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYT2 | 127833 | 11 | 0 | 19 | |
| GSE20123 | SYT2 | 127833 | 11 | 0 | 19 | |
| GSE43470 | SYT2 | 127833 | 6 | 0 | 37 | |
| GSE46452 | SYT2 | 127833 | 3 | 1 | 55 | |
| GSE47630 | SYT2 | 127833 | 14 | 0 | 26 | |
| GSE54993 | SYT2 | 127833 | 0 | 6 | 64 | |
| GSE54994 | SYT2 | 127833 | 15 | 0 | 38 | |
| GSE60625 | SYT2 | 127833 | 0 | 0 | 11 | |
| GSE74703 | SYT2 | 127833 | 6 | 0 | 30 | |
| GSE74704 | SYT2 | 127833 | 5 | 0 | 15 | |
| TCGA | SYT2 | 127833 | 43 | 4 | 49 |
Total number of gains: 114; Total number of losses: 11; Total Number of normals: 363.
Somatic mutations of SYT2:
Generating mutation plots.
Highly correlated genes for SYT2:
Showing top 20/1169 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYT2 | UFSP1 | 0.810886 | 3 | 0 | 3 |
| SYT2 | LRCH4 | 0.802381 | 3 | 0 | 3 |
| SYT2 | GDF7 | 0.792147 | 3 | 0 | 3 |
| SYT2 | INHBC | 0.74135 | 3 | 0 | 3 |
| SYT2 | CELF5 | 0.741333 | 3 | 0 | 3 |
| SYT2 | C10orf91 | 0.738712 | 3 | 0 | 3 |
| SYT2 | ZSWIM3 | 0.7379 | 3 | 0 | 3 |
| SYT2 | C1QL2 | 0.736629 | 3 | 0 | 3 |
| SYT2 | TDRD1 | 0.736016 | 5 | 0 | 5 |
| SYT2 | ABCA2 | 0.730408 | 3 | 0 | 3 |
| SYT2 | MAPK15 | 0.724162 | 3 | 0 | 3 |
| SYT2 | OR1D2 | 0.716882 | 6 | 0 | 6 |
| SYT2 | SPINT3 | 0.713993 | 7 | 0 | 6 |
| SYT2 | PAX6 | 0.712298 | 3 | 0 | 3 |
| SYT2 | DBX1 | 0.709767 | 3 | 0 | 3 |
| SYT2 | YY2 | 0.708498 | 3 | 0 | 3 |
| SYT2 | IL1F10 | 0.70786 | 4 | 0 | 3 |
| SYT2 | PHGR1 | 0.705588 | 3 | 0 | 3 |
| SYT2 | VWA2 | 0.702404 | 3 | 0 | 3 |
| SYT2 | VIPR2 | 0.701734 | 8 | 0 | 7 |
For details and further investigation, click here
