PEAK1

 

Full name: pseudopodium enriched atypical kinase 1 Alias Symbol: KIAA2002|sgk269
Type: protein-coding gene Cytoband: 15q24.3
Entrez ID: 79834 HGNC ID: HGNC:29431 Ensembl Gene: ENSG00000173517 OMIM ID: 614248

 

Expression of PEAK1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PEAK1 79834 225913_at -0.3210 0.5815
GSE20347 PEAK1 79834 220008_at 0.1834 0.1378
GSE23400 PEAK1 79834 220008_at -0.0584 0.1406
GSE26886 PEAK1 79834 225913_at 0.4388 0.0665
GSE29001 PEAK1 79834 220008_at -0.0088 0.9685
GSE38129 PEAK1 79834 220008_at 0.0427 0.7452
GSE45670 PEAK1 79834 225913_at -0.3844 0.0472
GSE53622 PEAK1 79834 71925 0.0041 0.9712
GSE53624 PEAK1 79834 63539 0.1046 0.3089
GSE63941 PEAK1 79834 225913_at -2.8800 0.0000
GSE77861 PEAK1 79834 220008_at 0.0255 0.7821
GSE97050 PEAK1 A_21_P0008759 -0.0320 0.8830
SRP007169 PEAK1 79834 RNAseq 1.9693 0.0000
SRP008496 PEAK1 79834 RNAseq 2.0938 0.0000
SRP064894 PEAK1 79834 RNAseq 0.5192 0.0748
SRP133303 PEAK1 79834 RNAseq 0.1960 0.3732
SRP159526 PEAK1 79834 RNAseq 0.2200 0.3614
SRP193095 PEAK1 79834 RNAseq 0.3500 0.0327
SRP219564 PEAK1 79834 RNAseq -0.2442 0.5104

Upregulated datasets: 2; Downregulated datasets: 1.  


 

Survival by PEAK1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of PEAK1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PEAK1 79834 8 1 21
GSE20123 PEAK1 79834 8 1 21
GSE43470 PEAK1 79834 4 5 34
GSE46452 PEAK1 79834 3 7 49
GSE47630 PEAK1 79834 8 10 22
GSE54993 PEAK1 79834 5 6 59
GSE54994 PEAK1 79834 5 6 42
GSE60625 PEAK1 79834 4 0 7
GSE74703 PEAK1 79834 4 3 29
GSE74704 PEAK1 79834 5 1 14
TCGA PEAK1 79834 15 16 65

Total number of gains: 69; Total number of losses: 56; Total Number of normals: 363.  


 

Somatic mutations of PEAK1:

 

Generating mutation plots.

 

Highly correlated genes for PEAK1:

 

Showing top 20/895 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PEAK1TCEAL70.77957404
PEAK1TNFRSF190.754082303
PEAK1SPATA90.741782303
PEAK1IL1RAPL20.740589404
PEAK1FOXN3-AS20.738389504
PEAK1KCTD70.73728303
PEAK1NTNG10.731479404
PEAK1ZNF4230.729591504
PEAK1SYDE10.725543706
PEAK1SYT110.723926706
PEAK1UBE2Q20.717399303
PEAK1NAP1L30.717046505
PEAK1MCAM0.715884605
PEAK1FIBIN0.715471504
PEAK1C1orf540.715406505
PEAK1C20orf1940.713031303
PEAK1STARD130.711848707
PEAK1FGFR10.710777606
PEAK1TNFSF80.710069404
PEAK1SLC39A130.705648404

For details and further investigation, click here