| Full name: chromosome 1 open reading frame 54 | Alias Symbol: FLJ23221 | ||
| Type: protein-coding gene | Cytoband: 1q21.2 | ||
| Entrez ID: 79630 | HGNC ID: HGNC:26258 | Ensembl Gene: ENSG00000118292 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C1orf54:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C1orf54 | 79630 | 219506_at | -0.2314 | 0.6938 | |
| GSE20347 | C1orf54 | 79630 | 219506_at | 0.3533 | 0.0620 | |
| GSE23400 | C1orf54 | 79630 | 219506_at | 0.0955 | 0.2379 | |
| GSE26886 | C1orf54 | 79630 | 219506_at | -0.0164 | 0.9568 | |
| GSE29001 | C1orf54 | 79630 | 219506_at | 0.3311 | 0.3368 | |
| GSE38129 | C1orf54 | 79630 | 219506_at | 0.0185 | 0.9515 | |
| GSE45670 | C1orf54 | 79630 | 219506_at | -0.7530 | 0.0019 | |
| GSE53622 | C1orf54 | 79630 | 36994 | 0.0846 | 0.4250 | |
| GSE53624 | C1orf54 | 79630 | 36994 | 0.3511 | 0.0001 | |
| GSE63941 | C1orf54 | 79630 | 219506_at | -4.6279 | 0.0000 | |
| GSE77861 | C1orf54 | 79630 | 219506_at | 0.2634 | 0.1131 | |
| GSE97050 | C1orf54 | 79630 | A_23_P74778 | -0.0653 | 0.7653 | |
| SRP007169 | C1orf54 | 79630 | RNAseq | 1.9239 | 0.0151 | |
| SRP008496 | C1orf54 | 79630 | RNAseq | 2.9647 | 0.0000 | |
| SRP064894 | C1orf54 | 79630 | RNAseq | 0.6163 | 0.0496 | |
| SRP133303 | C1orf54 | 79630 | RNAseq | 0.4226 | 0.1153 | |
| SRP159526 | C1orf54 | 79630 | RNAseq | -0.1545 | 0.6951 | |
| SRP193095 | C1orf54 | 79630 | RNAseq | 0.7633 | 0.0004 | |
| SRP219564 | C1orf54 | 79630 | RNAseq | 0.3629 | 0.5129 | |
| TCGA | C1orf54 | 79630 | RNAseq | 0.1242 | 0.3918 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by C1orf54 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C1orf54:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C1orf54 | 79630 | 15 | 0 | 15 | |
| GSE20123 | C1orf54 | 79630 | 15 | 0 | 15 | |
| GSE43470 | C1orf54 | 79630 | 6 | 1 | 36 | |
| GSE46452 | C1orf54 | 79630 | 2 | 1 | 56 | |
| GSE47630 | C1orf54 | 79630 | 14 | 0 | 26 | |
| GSE54993 | C1orf54 | 79630 | 0 | 3 | 67 | |
| GSE54994 | C1orf54 | 79630 | 15 | 0 | 38 | |
| GSE60625 | C1orf54 | 79630 | 0 | 0 | 11 | |
| GSE74703 | C1orf54 | 79630 | 6 | 1 | 29 | |
| GSE74704 | C1orf54 | 79630 | 7 | 0 | 13 | |
| TCGA | C1orf54 | 79630 | 38 | 2 | 56 |
Total number of gains: 118; Total number of losses: 8; Total Number of normals: 362.
Somatic mutations of C1orf54:
Generating mutation plots.
Highly correlated genes for C1orf54:
Showing top 20/1007 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C1orf54 | C11orf96 | 0.77659 | 4 | 0 | 4 |
| C1orf54 | FIBIN | 0.76052 | 5 | 0 | 5 |
| C1orf54 | LINC-PINT | 0.742496 | 3 | 0 | 3 |
| C1orf54 | LAMA4 | 0.742219 | 11 | 0 | 11 |
| C1orf54 | GPC6 | 0.741616 | 6 | 0 | 6 |
| C1orf54 | ZFPM2 | 0.738575 | 9 | 0 | 8 |
| C1orf54 | DCHS1 | 0.738181 | 8 | 0 | 7 |
| C1orf54 | SDC3 | 0.725818 | 6 | 0 | 6 |
| C1orf54 | RARRES2 | 0.722818 | 12 | 0 | 10 |
| C1orf54 | FBN1 | 0.717247 | 11 | 0 | 10 |
| C1orf54 | GLIPR2 | 0.716256 | 7 | 0 | 7 |
| C1orf54 | PEAK1 | 0.715406 | 5 | 0 | 5 |
| C1orf54 | OLFML3 | 0.710784 | 13 | 0 | 13 |
| C1orf54 | CNRIP1 | 0.70901 | 9 | 0 | 9 |
| C1orf54 | PLEKHO2 | 0.706582 | 11 | 0 | 9 |
| C1orf54 | YPEL2 | 0.705018 | 3 | 0 | 3 |
| C1orf54 | BICC1 | 0.703499 | 11 | 0 | 9 |
| C1orf54 | ANXA6 | 0.702776 | 12 | 0 | 9 |
| C1orf54 | TCEAL7 | 0.702737 | 7 | 0 | 7 |
| C1orf54 | ARHGEF6 | 0.702438 | 9 | 0 | 9 |
For details and further investigation, click here
