| Full name: zinc finger protein 423 | Alias Symbol: KIAA0760|OAZ|hOAZ|Ebfaz|Zfp104|NPHP14|JBTS19 | ||
| Type: protein-coding gene | Cytoband: 16q12.1 | ||
| Entrez ID: 23090 | HGNC ID: HGNC:16762 | Ensembl Gene: ENSG00000102935 | OMIM ID: 604557 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF423:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF423 | 23090 | 214761_at | -1.0973 | 0.1635 | |
| GSE20347 | ZNF423 | 23090 | 214761_at | -0.0022 | 0.9913 | |
| GSE23400 | ZNF423 | 23090 | 214761_at | -0.3673 | 0.0063 | |
| GSE26886 | ZNF423 | 23090 | 214761_at | 0.7970 | 0.0601 | |
| GSE29001 | ZNF423 | 23090 | 214761_at | -0.1116 | 0.7900 | |
| GSE38129 | ZNF423 | 23090 | 214761_at | -0.5624 | 0.1054 | |
| GSE45670 | ZNF423 | 23090 | 214761_at | -1.8541 | 0.0000 | |
| GSE53622 | ZNF423 | 23090 | 25514 | -0.5422 | 0.0000 | |
| GSE53624 | ZNF423 | 23090 | 25514 | -0.2932 | 0.0050 | |
| GSE63941 | ZNF423 | 23090 | 214761_at | -1.5685 | 0.0028 | |
| GSE77861 | ZNF423 | 23090 | 214761_at | 0.1416 | 0.1230 | |
| GSE97050 | ZNF423 | 23090 | A_23_P88880 | -0.1881 | 0.5236 | |
| SRP064894 | ZNF423 | 23090 | RNAseq | -0.4302 | 0.1726 | |
| SRP133303 | ZNF423 | 23090 | RNAseq | -0.9087 | 0.0018 | |
| SRP159526 | ZNF423 | 23090 | RNAseq | -0.4353 | 0.1272 | |
| SRP219564 | ZNF423 | 23090 | RNAseq | -0.0205 | 0.9803 | |
| TCGA | ZNF423 | 23090 | RNAseq | -0.5551 | 0.0009 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ZNF423 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF423:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF423 | 23090 | 4 | 1 | 25 | |
| GSE20123 | ZNF423 | 23090 | 3 | 1 | 26 | |
| GSE43470 | ZNF423 | 23090 | 2 | 7 | 34 | |
| GSE46452 | ZNF423 | 23090 | 38 | 1 | 20 | |
| GSE47630 | ZNF423 | 23090 | 11 | 7 | 22 | |
| GSE54993 | ZNF423 | 23090 | 2 | 5 | 63 | |
| GSE54994 | ZNF423 | 23090 | 6 | 10 | 37 | |
| GSE60625 | ZNF423 | 23090 | 4 | 0 | 7 | |
| GSE74703 | ZNF423 | 23090 | 2 | 4 | 30 | |
| GSE74704 | ZNF423 | 23090 | 3 | 1 | 16 | |
| TCGA | ZNF423 | 23090 | 26 | 12 | 58 |
Total number of gains: 101; Total number of losses: 49; Total Number of normals: 338.
Somatic mutations of ZNF423:
Generating mutation plots.
Highly correlated genes for ZNF423:
Showing top 20/1226 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF423 | EPDR1 | 0.805669 | 5 | 0 | 5 |
| ZNF423 | EMCN | 0.788256 | 5 | 0 | 5 |
| ZNF423 | DIXDC1 | 0.784271 | 8 | 0 | 8 |
| ZNF423 | LRRN4CL | 0.775177 | 6 | 0 | 6 |
| ZNF423 | PREX2 | 0.77396 | 3 | 0 | 3 |
| ZNF423 | SLIT2 | 0.77056 | 7 | 0 | 7 |
| ZNF423 | C1QTNF7 | 0.767714 | 4 | 0 | 4 |
| ZNF423 | CLASP1 | 0.767383 | 3 | 0 | 3 |
| ZNF423 | AGTR1 | 0.760815 | 8 | 0 | 8 |
| ZNF423 | ARMCX2 | 0.760075 | 7 | 0 | 7 |
| ZNF423 | DCHS1 | 0.759098 | 9 | 0 | 8 |
| ZNF423 | GLI2 | 0.754573 | 3 | 0 | 3 |
| ZNF423 | JAM3 | 0.749688 | 11 | 0 | 8 |
| ZNF423 | PDK2 | 0.748486 | 4 | 0 | 4 |
| ZNF423 | CLEC14A | 0.746723 | 4 | 0 | 4 |
| ZNF423 | LINC01279 | 0.745831 | 5 | 0 | 4 |
| ZNF423 | DAAM2 | 0.743125 | 9 | 0 | 9 |
| ZNF423 | LYVE1 | 0.742769 | 7 | 0 | 6 |
| ZNF423 | RSPO3 | 0.74244 | 6 | 0 | 5 |
| ZNF423 | HMCN1 | 0.740429 | 6 | 0 | 5 |
For details and further investigation, click here
