| Full name: PHD finger protein 21B | Alias Symbol: BHC80L|FLJ34161 | ||
| Type: protein-coding gene | Cytoband: 22q13.31 | ||
| Entrez ID: 112885 | HGNC ID: HGNC:25161 | Ensembl Gene: ENSG00000056487 | OMIM ID: 616727 |
| Drug and gene relationship at DGIdb | |||
Expression of PHF21B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHF21B | 112885 | 1560091_a_at | -0.0450 | 0.8664 | |
| GSE26886 | PHF21B | 112885 | 1562309_s_at | 0.4909 | 0.0079 | |
| GSE45670 | PHF21B | 112885 | 1560091_a_at | 0.0288 | 0.7886 | |
| GSE53622 | PHF21B | 112885 | 160586 | -0.3589 | 0.0000 | |
| GSE53624 | PHF21B | 112885 | 160586 | -0.5119 | 0.0000 | |
| GSE63941 | PHF21B | 112885 | 1562309_s_at | 0.7836 | 0.2484 | |
| GSE77861 | PHF21B | 112885 | 1560091_a_at | -0.0481 | 0.6285 | |
| GSE97050 | PHF21B | 112885 | A_33_P3280666 | -0.0855 | 0.6767 | |
| TCGA | PHF21B | 112885 | RNAseq | -0.3530 | 0.5901 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PHF21B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHF21B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PHF21B | 112885 | 5 | 7 | 18 | |
| GSE20123 | PHF21B | 112885 | 4 | 6 | 20 | |
| GSE43470 | PHF21B | 112885 | 2 | 6 | 35 | |
| GSE46452 | PHF21B | 112885 | 31 | 2 | 26 | |
| GSE47630 | PHF21B | 112885 | 9 | 4 | 27 | |
| GSE54993 | PHF21B | 112885 | 3 | 6 | 61 | |
| GSE54994 | PHF21B | 112885 | 11 | 8 | 34 | |
| GSE60625 | PHF21B | 112885 | 5 | 0 | 6 | |
| GSE74703 | PHF21B | 112885 | 2 | 4 | 30 | |
| GSE74704 | PHF21B | 112885 | 2 | 3 | 15 | |
| TCGA | PHF21B | 112885 | 26 | 15 | 55 |
Total number of gains: 100; Total number of losses: 61; Total Number of normals: 327.
Somatic mutations of PHF21B:
Generating mutation plots.
Highly correlated genes for PHF21B:
Showing top 20/244 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHF21B | SCARA5 | 0.825705 | 3 | 0 | 3 |
| PHF21B | SRRM3 | 0.819852 | 3 | 0 | 3 |
| PHF21B | TEX13A | 0.779289 | 3 | 0 | 3 |
| PHF21B | CLDN24 | 0.776016 | 3 | 0 | 3 |
| PHF21B | BMP10 | 0.74701 | 3 | 0 | 3 |
| PHF21B | CDH10 | 0.745738 | 3 | 0 | 3 |
| PHF21B | ENTPD8 | 0.742768 | 3 | 0 | 3 |
| PHF21B | ZCWPW1 | 0.73536 | 3 | 0 | 3 |
| PHF21B | FRMD1 | 0.717705 | 3 | 0 | 3 |
| PHF21B | AGAP2 | 0.710124 | 3 | 0 | 3 |
| PHF21B | ADAP1 | 0.710089 | 3 | 0 | 3 |
| PHF21B | GDF7 | 0.708653 | 3 | 0 | 3 |
| PHF21B | RAD52 | 0.705669 | 3 | 0 | 3 |
| PHF21B | OR2H1 | 0.704029 | 3 | 0 | 3 |
| PHF21B | MYO15B | 0.699329 | 3 | 0 | 3 |
| PHF21B | OTOF | 0.698795 | 6 | 0 | 5 |
| PHF21B | TMEM151B | 0.697191 | 5 | 0 | 4 |
| PHF21B | KCNMB2 | 0.691964 | 3 | 0 | 3 |
| PHF21B | SAMD4A | 0.688041 | 3 | 0 | 3 |
| PHF21B | OR1F1 | 0.683633 | 4 | 0 | 3 |
For details and further investigation, click here
