| Full name: bone morphogenetic protein 10 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p13.3 | ||
| Entrez ID: 27302 | HGNC ID: HGNC:20869 | Ensembl Gene: ENSG00000163217 | OMIM ID: 608748 |
| Drug and gene relationship at DGIdb | |||
Expression of BMP10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BMP10 | 27302 | 208292_at | 0.0556 | 0.8394 | |
| GSE20347 | BMP10 | 27302 | 208292_at | -0.0170 | 0.8210 | |
| GSE23400 | BMP10 | 27302 | 208292_at | -0.1620 | 0.0001 | |
| GSE26886 | BMP10 | 27302 | 208292_at | 0.1514 | 0.1873 | |
| GSE29001 | BMP10 | 27302 | 208292_at | -0.0894 | 0.6667 | |
| GSE38129 | BMP10 | 27302 | 208292_at | -0.1230 | 0.1200 | |
| GSE45670 | BMP10 | 27302 | 208292_at | 0.1522 | 0.0732 | |
| GSE53622 | BMP10 | 27302 | 111366 | 0.1395 | 0.0565 | |
| GSE53624 | BMP10 | 27302 | 111366 | 0.1373 | 0.0436 | |
| GSE63941 | BMP10 | 27302 | 208292_at | -0.0808 | 0.6686 | |
| GSE77861 | BMP10 | 27302 | 208292_at | -0.1955 | 0.1730 | |
| GSE97050 | BMP10 | 27302 | A_23_P131588 | 0.0205 | 0.9272 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by BMP10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BMP10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BMP10 | 27302 | 11 | 0 | 19 | |
| GSE20123 | BMP10 | 27302 | 11 | 0 | 19 | |
| GSE43470 | BMP10 | 27302 | 6 | 0 | 37 | |
| GSE46452 | BMP10 | 27302 | 2 | 3 | 54 | |
| GSE47630 | BMP10 | 27302 | 7 | 0 | 33 | |
| GSE54993 | BMP10 | 27302 | 0 | 6 | 64 | |
| GSE54994 | BMP10 | 27302 | 12 | 0 | 41 | |
| GSE60625 | BMP10 | 27302 | 0 | 3 | 8 | |
| GSE74703 | BMP10 | 27302 | 6 | 0 | 30 | |
| GSE74704 | BMP10 | 27302 | 9 | 0 | 11 | |
| TCGA | BMP10 | 27302 | 36 | 2 | 58 |
Total number of gains: 100; Total number of losses: 14; Total Number of normals: 374.
Somatic mutations of BMP10:
Generating mutation plots.
Highly correlated genes for BMP10:
Showing top 20/649 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BMP10 | PGC | 0.766285 | 3 | 0 | 3 |
| BMP10 | VEPH1 | 0.763058 | 3 | 0 | 3 |
| BMP10 | CDH2 | 0.758814 | 3 | 0 | 3 |
| BMP10 | MFSD6L | 0.756014 | 3 | 0 | 3 |
| BMP10 | PHF21B | 0.74701 | 3 | 0 | 3 |
| BMP10 | RAD52 | 0.738864 | 4 | 0 | 4 |
| BMP10 | MAPK15 | 0.730127 | 3 | 0 | 3 |
| BMP10 | SHROOM1 | 0.724795 | 3 | 0 | 3 |
| BMP10 | STK32C | 0.714559 | 3 | 0 | 3 |
| BMP10 | MGAT5B | 0.698121 | 3 | 0 | 3 |
| BMP10 | DHRS7C | 0.687971 | 3 | 0 | 3 |
| BMP10 | GPT | 0.684116 | 4 | 0 | 3 |
| BMP10 | WNT1 | 0.682693 | 3 | 0 | 3 |
| BMP10 | TREM1 | 0.680884 | 3 | 0 | 3 |
| BMP10 | SHC2 | 0.680501 | 3 | 0 | 3 |
| BMP10 | OR10H1 | 0.67788 | 5 | 0 | 5 |
| BMP10 | HAAO | 0.676781 | 4 | 0 | 4 |
| BMP10 | FGF14 | 0.675901 | 3 | 0 | 3 |
| BMP10 | PGAM2 | 0.674744 | 4 | 0 | 4 |
| BMP10 | BRSK1 | 0.674587 | 4 | 0 | 3 |
For details and further investigation, click here
