| Full name: sterile alpha motif domain containing 4A | Alias Symbol: KIAA1053|DKFZP434H0350|Smaug|SMG|SMGA|hSmaug1 | ||
| Type: protein-coding gene | Cytoband: 14q22.2 | ||
| Entrez ID: 23034 | HGNC ID: HGNC:23023 | Ensembl Gene: ENSG00000020577 | OMIM ID: 610747 |
| Drug and gene relationship at DGIdb | |||
Expression of SAMD4A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SAMD4A | 23034 | 212845_at | -0.8566 | 0.3586 | |
| GSE20347 | SAMD4A | 23034 | 212845_at | 0.6421 | 0.0754 | |
| GSE23400 | SAMD4A | 23034 | 212845_at | -0.0403 | 0.8143 | |
| GSE26886 | SAMD4A | 23034 | 212845_at | 1.2483 | 0.0118 | |
| GSE29001 | SAMD4A | 23034 | 212845_at | 0.2941 | 0.4609 | |
| GSE38129 | SAMD4A | 23034 | 212845_at | -0.1392 | 0.7861 | |
| GSE45670 | SAMD4A | 23034 | 212845_at | -1.4989 | 0.0048 | |
| GSE53622 | SAMD4A | 23034 | 118447 | -0.2696 | 0.0000 | |
| GSE53624 | SAMD4A | 23034 | 118447 | -0.1943 | 0.0360 | |
| GSE63941 | SAMD4A | 23034 | 212845_at | -2.2997 | 0.0614 | |
| GSE77861 | SAMD4A | 23034 | 215496_at | -0.0469 | 0.6657 | |
| GSE97050 | SAMD4A | 23034 | A_33_P3344292 | -0.1102 | 0.6185 | |
| SRP007169 | SAMD4A | 23034 | RNAseq | 1.5838 | 0.0069 | |
| SRP008496 | SAMD4A | 23034 | RNAseq | 1.8889 | 0.0000 | |
| SRP064894 | SAMD4A | 23034 | RNAseq | 0.0301 | 0.9422 | |
| SRP133303 | SAMD4A | 23034 | RNAseq | 0.1264 | 0.7672 | |
| SRP159526 | SAMD4A | 23034 | RNAseq | -0.3175 | 0.3295 | |
| SRP193095 | SAMD4A | 23034 | RNAseq | 2.1209 | 0.0000 | |
| SRP219564 | SAMD4A | 23034 | RNAseq | 0.2761 | 0.5917 | |
| TCGA | SAMD4A | 23034 | RNAseq | -0.4283 | 0.0011 |
Upregulated datasets: 4; Downregulated datasets: 1.
Survival by SAMD4A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SAMD4A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SAMD4A | 23034 | 8 | 3 | 19 | |
| GSE20123 | SAMD4A | 23034 | 8 | 3 | 19 | |
| GSE43470 | SAMD4A | 23034 | 9 | 1 | 33 | |
| GSE46452 | SAMD4A | 23034 | 16 | 3 | 40 | |
| GSE47630 | SAMD4A | 23034 | 11 | 10 | 19 | |
| GSE54993 | SAMD4A | 23034 | 3 | 8 | 59 | |
| GSE54994 | SAMD4A | 23034 | 19 | 4 | 30 | |
| GSE60625 | SAMD4A | 23034 | 0 | 2 | 9 | |
| GSE74703 | SAMD4A | 23034 | 8 | 1 | 27 | |
| GSE74704 | SAMD4A | 23034 | 3 | 2 | 15 | |
| TCGA | SAMD4A | 23034 | 33 | 13 | 50 |
Total number of gains: 118; Total number of losses: 50; Total Number of normals: 320.
Somatic mutations of SAMD4A:
Generating mutation plots.
Highly correlated genes for SAMD4A:
Showing top 20/239 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SAMD4A | GDF7 | 0.872952 | 3 | 0 | 3 |
| SAMD4A | KIRREL2 | 0.814624 | 3 | 0 | 3 |
| SAMD4A | YY2 | 0.787535 | 3 | 0 | 3 |
| SAMD4A | BEST4 | 0.781789 | 3 | 0 | 3 |
| SAMD4A | UFSP1 | 0.778402 | 3 | 0 | 3 |
| SAMD4A | LHX9 | 0.776208 | 3 | 0 | 3 |
| SAMD4A | DBX1 | 0.764585 | 3 | 0 | 3 |
| SAMD4A | C1QL2 | 0.752589 | 3 | 0 | 3 |
| SAMD4A | LRSAM1 | 0.752271 | 3 | 0 | 3 |
| SAMD4A | KRTAP6-1 | 0.746745 | 3 | 0 | 3 |
| SAMD4A | OTOG | 0.745238 | 3 | 0 | 3 |
| SAMD4A | INSC | 0.744703 | 5 | 0 | 5 |
| SAMD4A | TPRX1 | 0.74464 | 3 | 0 | 3 |
| SAMD4A | MYL7 | 0.743263 | 4 | 0 | 4 |
| SAMD4A | LACRT | 0.736854 | 3 | 0 | 3 |
| SAMD4A | SUN5 | 0.73638 | 3 | 0 | 3 |
| SAMD4A | CTU1 | 0.728002 | 3 | 0 | 3 |
| SAMD4A | ZNF497 | 0.727073 | 3 | 0 | 3 |
| SAMD4A | HCRTR1 | 0.725888 | 3 | 0 | 3 |
| SAMD4A | TSPAN11 | 0.724594 | 4 | 0 | 3 |
For details and further investigation, click here
