PIP

 

Full name: prolactin induced protein Alias Symbol: GCDFP-15|GCDFP15|GPIP4
Type: protein-coding gene Cytoband: 7q34
Entrez ID: 5304 HGNC ID: HGNC:8993 Ensembl Gene: ENSG00000159763 OMIM ID: 176720
Drug and gene relationship at DGIdb

 

Expression of PIP:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PIP 5304 206509_at -0.3010 0.3326
GSE20347 PIP 5304 206509_at -0.0570 0.5054
GSE23400 PIP 5304 206509_at -0.1283 0.0002
GSE26886 PIP 5304 206509_at -0.0470 0.7394
GSE29001 PIP 5304 206509_at -0.0832 0.6505
GSE38129 PIP 5304 206509_at -0.2401 0.0044
GSE45670 PIP 5304 206509_at -0.2695 0.0505
GSE53622 PIP 5304 52266 -0.4459 0.0421
GSE53624 PIP 5304 52266 -1.0644 0.0000
GSE63941 PIP 5304 206509_at 0.1692 0.3663
GSE77861 PIP 5304 206509_at -0.1344 0.2146
TCGA PIP 5304 RNAseq 1.8160 0.3531

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by PIP expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PIP:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PIP 5304 4 2 24
GSE20123 PIP 5304 4 2 24
GSE43470 PIP 5304 2 4 37
GSE46452 PIP 5304 7 2 50
GSE47630 PIP 5304 6 7 27
GSE54993 PIP 5304 3 4 63
GSE54994 PIP 5304 5 8 40
GSE60625 PIP 5304 0 0 11
GSE74703 PIP 5304 2 4 30
GSE74704 PIP 5304 2 2 16
TCGA PIP 5304 28 24 44

Total number of gains: 63; Total number of losses: 59; Total Number of normals: 366.  


 

Somatic mutations of PIP:

 

Generating mutation plots.

 

Highly correlated genes for PIP:

 

Showing top 20/546 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PIPZG16B0.752395404
PIPBPIFB10.736669404
PIPLCN10.723401606
PIPC6orf580.71677504
PIPAZGP10.710618505
PIPBPIFB20.705505606
PIPREG3A0.701698303
PIPSSTR5-AS10.694821303
PIPSCGB3A10.69356504
PIPSCGB1D20.687539807
PIPNDOR10.685667404
PIPADRB30.680164404
PIPDIO10.676407303
PIPCHRM10.673104403
PIPPLIN10.671724504
PIPEDA2R0.671139404
PIPCHST40.67113808
PIPIGH0.660552303
PIPMUC70.65821705
PIPASCL30.656876605

For details and further investigation, click here