| Full name: zymogen granule protein 16B | Alias Symbol: HRPE773|PRO1567|JCLN2 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 124220 | HGNC ID: HGNC:30456 | Ensembl Gene: ENSG00000162078 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZG16B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZG16B | 124220 | 228058_at | -2.4627 | 0.1724 | |
| GSE26886 | ZG16B | 124220 | 228058_at | 0.1372 | 0.6567 | |
| GSE45670 | ZG16B | 124220 | 228058_at | -1.0534 | 0.1968 | |
| GSE53622 | ZG16B | 124220 | 99638 | -2.1473 | 0.0000 | |
| GSE53624 | ZG16B | 124220 | 99638 | -3.0700 | 0.0000 | |
| GSE63941 | ZG16B | 124220 | 228058_at | 0.8757 | 0.3111 | |
| GSE77861 | ZG16B | 124220 | 228058_at | -0.1376 | 0.5217 | |
| GSE97050 | ZG16B | 124220 | A_23_P118203 | -0.4403 | 0.6158 | |
| SRP133303 | ZG16B | 124220 | RNAseq | -5.7842 | 0.0000 | |
| SRP159526 | ZG16B | 124220 | RNAseq | -2.4516 | 0.1630 | |
| TCGA | ZG16B | 124220 | RNAseq | -1.3277 | 0.0299 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ZG16B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZG16B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZG16B | 124220 | 5 | 5 | 20 | |
| GSE20123 | ZG16B | 124220 | 5 | 4 | 21 | |
| GSE43470 | ZG16B | 124220 | 4 | 7 | 32 | |
| GSE46452 | ZG16B | 124220 | 38 | 1 | 20 | |
| GSE47630 | ZG16B | 124220 | 13 | 6 | 21 | |
| GSE54993 | ZG16B | 124220 | 3 | 5 | 62 | |
| GSE54994 | ZG16B | 124220 | 5 | 9 | 39 | |
| GSE60625 | ZG16B | 124220 | 4 | 0 | 7 | |
| GSE74703 | ZG16B | 124220 | 4 | 5 | 27 | |
| GSE74704 | ZG16B | 124220 | 3 | 2 | 15 | |
| TCGA | ZG16B | 124220 | 19 | 13 | 64 |
Total number of gains: 103; Total number of losses: 57; Total Number of normals: 328.
Somatic mutations of ZG16B:
Generating mutation plots.
Highly correlated genes for ZG16B:
Showing top 20/83 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZG16B | PIGR | 0.848701 | 4 | 0 | 4 |
| ZG16B | MUC7 | 0.846173 | 4 | 0 | 4 |
| ZG16B | LRRC26 | 0.826152 | 3 | 0 | 3 |
| ZG16B | BPIFB2 | 0.818174 | 6 | 0 | 6 |
| ZG16B | C6orf58 | 0.776161 | 6 | 0 | 5 |
| ZG16B | PIP | 0.752395 | 4 | 0 | 4 |
| ZG16B | SCGB3A1 | 0.751253 | 7 | 0 | 6 |
| ZG16B | STATH | 0.74943 | 6 | 0 | 6 |
| ZG16B | MUC5B | 0.745206 | 7 | 0 | 5 |
| ZG16B | SCGB1D2 | 0.736173 | 5 | 0 | 5 |
| ZG16B | PRH2 | 0.726124 | 3 | 0 | 3 |
| ZG16B | NXPE4 | 0.724486 | 4 | 0 | 4 |
| ZG16B | NKX3-1 | 0.723813 | 5 | 0 | 5 |
| ZG16B | MSMB | 0.722319 | 6 | 0 | 5 |
| ZG16B | TSPAN8 | 0.718624 | 6 | 0 | 5 |
| ZG16B | BPIFB1 | 0.708271 | 8 | 0 | 6 |
| ZG16B | AZGP1 | 0.701085 | 7 | 0 | 5 |
| ZG16B | SSTR5-AS1 | 0.69811 | 4 | 0 | 3 |
| ZG16B | GP2 | 0.687907 | 5 | 0 | 4 |
| ZG16B | TFF3 | 0.671381 | 7 | 0 | 5 |
For details and further investigation, click here
