| Full name: pancreatic lipase related protein 2 (gene/pseudogene) | Alias Symbol: PLRP2 | ||
| Type: protein-coding gene | Cytoband: 10q25.3 | ||
| Entrez ID: 5408 | HGNC ID: HGNC:9157 | Ensembl Gene: ENSG00000266200 | OMIM ID: 604423 |
| Drug and gene relationship at DGIdb | |||
Expression of PNLIPRP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PNLIPRP2 | 5408 | 211766_s_at | 0.0513 | 0.8085 | |
| GSE20347 | PNLIPRP2 | 5408 | 211766_s_at | 0.0614 | 0.2640 | |
| GSE23400 | PNLIPRP2 | 5408 | 211766_s_at | -0.0772 | 0.0002 | |
| GSE26886 | PNLIPRP2 | 5408 | 211766_s_at | -0.1571 | 0.0839 | |
| GSE29001 | PNLIPRP2 | 5408 | 211766_s_at | -0.0127 | 0.9156 | |
| GSE38129 | PNLIPRP2 | 5408 | 211766_s_at | -0.0932 | 0.2306 | |
| GSE45670 | PNLIPRP2 | 5408 | 211766_s_at | -0.0633 | 0.3447 | |
| GSE53622 | PNLIPRP2 | 5408 | 36114 | -1.7413 | 0.0000 | |
| GSE53624 | PNLIPRP2 | 5408 | 36114 | -1.8710 | 0.0000 | |
| GSE63941 | PNLIPRP2 | 5408 | 211766_s_at | 0.0241 | 0.9134 | |
| GSE77861 | PNLIPRP2 | 5408 | 211766_s_at | 0.0504 | 0.4921 | |
| TCGA | PNLIPRP2 | 5408 | RNAseq | -6.0859 | 0.0021 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by PNLIPRP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PNLIPRP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PNLIPRP2 | 5408 | 1 | 7 | 22 | |
| GSE20123 | PNLIPRP2 | 5408 | 1 | 7 | 22 | |
| GSE43470 | PNLIPRP2 | 5408 | 0 | 9 | 34 | |
| GSE46452 | PNLIPRP2 | 5408 | 0 | 11 | 48 | |
| GSE47630 | PNLIPRP2 | 5408 | 2 | 14 | 24 | |
| GSE54993 | PNLIPRP2 | 5408 | 8 | 0 | 62 | |
| GSE54994 | PNLIPRP2 | 5408 | 1 | 9 | 43 | |
| GSE60625 | PNLIPRP2 | 5408 | 0 | 0 | 11 | |
| GSE74703 | PNLIPRP2 | 5408 | 0 | 6 | 30 | |
| GSE74704 | PNLIPRP2 | 5408 | 1 | 3 | 16 | |
| TCGA | PNLIPRP2 | 5408 | 4 | 28 | 64 |
Total number of gains: 18; Total number of losses: 94; Total Number of normals: 376.
Somatic mutations of PNLIPRP2:
Generating mutation plots.
Highly correlated genes for PNLIPRP2:
Showing top 20/93 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PNLIPRP2 | CRX | 0.705023 | 4 | 0 | 3 |
| PNLIPRP2 | TCEANC2 | 0.678402 | 3 | 0 | 3 |
| PNLIPRP2 | DRD5 | 0.667101 | 3 | 0 | 3 |
| PNLIPRP2 | CMTM1 | 0.647102 | 3 | 0 | 3 |
| PNLIPRP2 | RNH1 | 0.642543 | 3 | 0 | 3 |
| PNLIPRP2 | C3orf20 | 0.636061 | 3 | 0 | 3 |
| PNLIPRP2 | GABRB2 | 0.629163 | 3 | 0 | 3 |
| PNLIPRP2 | KCNJ4 | 0.622042 | 3 | 0 | 3 |
| PNLIPRP2 | FAM131B | 0.621881 | 3 | 0 | 3 |
| PNLIPRP2 | ATRNL1 | 0.616553 | 5 | 0 | 4 |
| PNLIPRP2 | NTNG1 | 0.615518 | 5 | 0 | 4 |
| PNLIPRP2 | OTOF | 0.612399 | 4 | 0 | 3 |
| PNLIPRP2 | HCG22 | 0.609843 | 3 | 0 | 3 |
| PNLIPRP2 | CCDC7 | 0.606567 | 5 | 0 | 4 |
| PNLIPRP2 | HECTD1 | 0.60124 | 3 | 0 | 3 |
| PNLIPRP2 | MRVI1-AS1 | 0.59977 | 3 | 0 | 3 |
| PNLIPRP2 | SLC17A3 | 0.599355 | 3 | 0 | 3 |
| PNLIPRP2 | IL9 | 0.597489 | 3 | 0 | 3 |
| PNLIPRP2 | PRAMEF12 | 0.595712 | 4 | 0 | 4 |
| PNLIPRP2 | CPNE6 | 0.593312 | 4 | 0 | 3 |
For details and further investigation, click here
