| Full name: copine 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 9362 | HGNC ID: HGNC:2319 | Ensembl Gene: ENSG00000100884 | OMIM ID: 605688 |
| Drug and gene relationship at DGIdb | |||
Expression of CPNE6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPNE6 | 9362 | 215700_x_at | 0.0281 | 0.9394 | |
| GSE20347 | CPNE6 | 9362 | 215700_x_at | 0.1254 | 0.2211 | |
| GSE23400 | CPNE6 | 9362 | 215700_x_at | -0.1335 | 0.0001 | |
| GSE26886 | CPNE6 | 9362 | 215700_x_at | 0.2235 | 0.0611 | |
| GSE29001 | CPNE6 | 9362 | 215700_x_at | -0.0617 | 0.7639 | |
| GSE38129 | CPNE6 | 9362 | 215700_x_at | -0.0891 | 0.5134 | |
| GSE45670 | CPNE6 | 9362 | 215700_x_at | 0.0426 | 0.6542 | |
| GSE53622 | CPNE6 | 9362 | 140195 | -2.6352 | 0.0000 | |
| GSE53624 | CPNE6 | 9362 | 140195 | -2.1652 | 0.0000 | |
| GSE63941 | CPNE6 | 9362 | 215700_x_at | 0.4157 | 0.0049 | |
| GSE77861 | CPNE6 | 9362 | 215700_x_at | -0.0468 | 0.7470 | |
| GSE97050 | CPNE6 | 9362 | A_23_P151598 | -0.3481 | 0.1736 | |
| SRP133303 | CPNE6 | 9362 | RNAseq | -2.1959 | 0.0000 | |
| SRP159526 | CPNE6 | 9362 | RNAseq | -3.7747 | 0.0000 | |
| TCGA | CPNE6 | 9362 | RNAseq | -2.8706 | 0.0062 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by CPNE6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CPNE6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPNE6 | 9362 | 8 | 3 | 19 | |
| GSE20123 | CPNE6 | 9362 | 8 | 3 | 19 | |
| GSE43470 | CPNE6 | 9362 | 8 | 2 | 33 | |
| GSE46452 | CPNE6 | 9362 | 16 | 2 | 41 | |
| GSE47630 | CPNE6 | 9362 | 11 | 10 | 19 | |
| GSE54993 | CPNE6 | 9362 | 3 | 11 | 56 | |
| GSE54994 | CPNE6 | 9362 | 18 | 5 | 30 | |
| GSE60625 | CPNE6 | 9362 | 0 | 2 | 9 | |
| GSE74703 | CPNE6 | 9362 | 7 | 2 | 27 | |
| GSE74704 | CPNE6 | 9362 | 3 | 2 | 15 | |
| TCGA | CPNE6 | 9362 | 27 | 13 | 56 |
Total number of gains: 109; Total number of losses: 55; Total Number of normals: 324.
Somatic mutations of CPNE6:
Generating mutation plots.
Highly correlated genes for CPNE6:
Showing top 20/859 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPNE6 | OR10G8 | 0.852567 | 3 | 0 | 3 |
| CPNE6 | FAM163B | 0.819112 | 3 | 0 | 3 |
| CPNE6 | OR2Z1 | 0.776239 | 3 | 0 | 3 |
| CPNE6 | KRTAP20-1 | 0.775016 | 3 | 0 | 3 |
| CPNE6 | KLHL10 | 0.766079 | 4 | 0 | 3 |
| CPNE6 | CYP3A4 | 0.765212 | 4 | 0 | 4 |
| CPNE6 | MASP2 | 0.764725 | 6 | 0 | 6 |
| CPNE6 | SFTPB | 0.762928 | 5 | 0 | 5 |
| CPNE6 | IFNA4 | 0.761963 | 4 | 0 | 4 |
| CPNE6 | HOXD9 | 0.760366 | 3 | 0 | 3 |
| CPNE6 | KIR2DS2 | 0.752626 | 3 | 0 | 3 |
| CPNE6 | MUC22 | 0.744756 | 3 | 0 | 3 |
| CPNE6 | OR51E2 | 0.739291 | 4 | 0 | 4 |
| CPNE6 | MFSD2B | 0.737652 | 3 | 0 | 3 |
| CPNE6 | PHLDB3 | 0.736858 | 4 | 0 | 4 |
| CPNE6 | PRKAR1B | 0.736088 | 4 | 0 | 4 |
| CPNE6 | IPO13 | 0.734449 | 3 | 0 | 3 |
| CPNE6 | TEN1 | 0.729765 | 3 | 0 | 3 |
| CPNE6 | SPATA19 | 0.727132 | 3 | 0 | 3 |
| CPNE6 | NCCRP1 | 0.726073 | 3 | 0 | 3 |
For details and further investigation, click here
