CMTM1

 

Full name: CKLF like MARVEL transmembrane domain containing 1 Alias Symbol: CKLFH1a|CKLFH
Type: protein-coding gene Cytoband: 16q21
Entrez ID: 113540 HGNC ID: HGNC:19172 Ensembl Gene: ENSG00000089505 OMIM ID: 607884
Drug and gene relationship at DGIdb

 

Expression of CMTM1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CMTM1 113540 231219_at 0.4562 0.1259
GSE26886 CMTM1 113540 1555738_at -0.1674 0.1239
GSE45670 CMTM1 113540 231219_at -0.0317 0.8615
GSE53622 CMTM1 113540 612 -1.4981 0.0000
GSE53624 CMTM1 113540 612 -1.4264 0.0000
GSE63941 CMTM1 113540 231219_at 0.4683 0.2003
GSE77861 CMTM1 113540 1555738_at -0.1728 0.2407
GSE97050 CMTM1 113540 A_23_P106661 -0.0063 0.9873
SRP133303 CMTM1 113540 RNAseq 0.8435 0.0008
SRP159526 CMTM1 113540 RNAseq 1.6320 0.0092
SRP193095 CMTM1 113540 RNAseq 0.7415 0.0000
SRP219564 CMTM1 113540 RNAseq 1.3633 0.0304
TCGA CMTM1 113540 RNAseq 0.4230 0.0009

Upregulated datasets: 2; Downregulated datasets: 2.  


 

Survival by CMTM1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CMTM1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CMTM1 113540 8 2 20
GSE20123 CMTM1 113540 8 2 20
GSE43470 CMTM1 113540 1 8 34
GSE46452 CMTM1 113540 38 1 20
GSE47630 CMTM1 113540 10 8 22
GSE54993 CMTM1 113540 2 4 64
GSE54994 CMTM1 113540 8 10 35
GSE60625 CMTM1 113540 4 0 7
GSE74703 CMTM1 113540 1 5 30
GSE74704 CMTM1 113540 5 1 14
TCGA CMTM1 113540 30 11 55

Total number of gains: 115; Total number of losses: 52; Total Number of normals: 321.  


 

Somatic mutations of CMTM1:

 

Generating mutation plots.

 

Highly correlated genes for CMTM1:

 

Showing top 20/145 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CMTM1HYAL10.725843303
CMTM1PASD10.717007303
CMTM1ARFRP10.689935303
CMTM1PRAM10.679196303
CMTM1UPB10.66599404
CMTM1TMPRSS11A0.663259303
CMTM1ACOX30.660826303
CMTM1OR5AS10.656295303
CMTM1ACOT80.654649504
CMTM1PRM10.6524303
CMTM1PNLIPRP20.647102303
CMTM1CTCFL0.643265303
CMTM1AP1G20.642928303
CMTM1TRMT440.639672303
CMTM1CLEC4M0.635564303
CMTM1MORN30.633478303
CMTM1NCCRP10.629668303
CMTM1PDCL20.628865404
CMTM1MAGEC20.625949303
CMTM1LRRC460.622537303

For details and further investigation, click here