| Full name: ribonuclease/angiogenin inhibitor 1 | Alias Symbol: RAI | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 6050 | HGNC ID: HGNC:10074 | Ensembl Gene: ENSG00000023191 | OMIM ID: 173320 |
| Drug and gene relationship at DGIdb | |||
Expression of RNH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNH1 | 6050 | 206050_s_at | -0.7094 | 0.1211 | |
| GSE20347 | RNH1 | 6050 | 206050_s_at | -0.8563 | 0.0000 | |
| GSE23400 | RNH1 | 6050 | 206050_s_at | -0.5410 | 0.0000 | |
| GSE26886 | RNH1 | 6050 | 206050_s_at | -1.3463 | 0.0000 | |
| GSE29001 | RNH1 | 6050 | 206050_s_at | -0.6529 | 0.0349 | |
| GSE38129 | RNH1 | 6050 | 206050_s_at | -0.7160 | 0.0000 | |
| GSE45670 | RNH1 | 6050 | 206050_s_at | -0.4172 | 0.0020 | |
| GSE53622 | RNH1 | 6050 | 49435 | -1.0239 | 0.0000 | |
| GSE53624 | RNH1 | 6050 | 49230 | -1.5173 | 0.0000 | |
| GSE63941 | RNH1 | 6050 | 206050_s_at | -0.4228 | 0.2250 | |
| GSE77861 | RNH1 | 6050 | 206050_s_at | -0.5380 | 0.1042 | |
| GSE97050 | RNH1 | 6050 | A_24_P415601 | -1.4423 | 0.0976 | |
| SRP007169 | RNH1 | 6050 | RNAseq | -2.1878 | 0.0000 | |
| SRP008496 | RNH1 | 6050 | RNAseq | -1.9806 | 0.0000 | |
| SRP064894 | RNH1 | 6050 | RNAseq | -0.4108 | 0.1081 | |
| SRP133303 | RNH1 | 6050 | RNAseq | -0.7774 | 0.0000 | |
| SRP159526 | RNH1 | 6050 | RNAseq | -1.2188 | 0.0001 | |
| SRP193095 | RNH1 | 6050 | RNAseq | -0.7690 | 0.0000 | |
| SRP219564 | RNH1 | 6050 | RNAseq | -0.4861 | 0.0123 | |
| TCGA | RNH1 | 6050 | RNAseq | 0.0417 | 0.3959 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by RNH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNH1 | 6050 | 1 | 11 | 18 | |
| GSE20123 | RNH1 | 6050 | 1 | 12 | 17 | |
| GSE43470 | RNH1 | 6050 | 1 | 10 | 32 | |
| GSE46452 | RNH1 | 6050 | 7 | 8 | 44 | |
| GSE47630 | RNH1 | 6050 | 4 | 12 | 24 | |
| GSE54993 | RNH1 | 6050 | 3 | 2 | 65 | |
| GSE54994 | RNH1 | 6050 | 1 | 12 | 40 | |
| GSE60625 | RNH1 | 6050 | 0 | 0 | 11 | |
| GSE74703 | RNH1 | 6050 | 1 | 8 | 27 | |
| GSE74704 | RNH1 | 6050 | 0 | 8 | 12 | |
| TCGA | RNH1 | 6050 | 8 | 38 | 50 |
Total number of gains: 27; Total number of losses: 121; Total Number of normals: 340.
Somatic mutations of RNH1:
Generating mutation plots.
Highly correlated genes for RNH1:
Showing top 20/1342 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNH1 | VSIG10L | 0.773821 | 6 | 0 | 6 |
| RNH1 | CYSRT1 | 0.766167 | 6 | 0 | 6 |
| RNH1 | TCP11L2 | 0.764612 | 5 | 0 | 5 |
| RNH1 | ABLIM1 | 0.761504 | 11 | 0 | 11 |
| RNH1 | FCHO2 | 0.760227 | 7 | 0 | 7 |
| RNH1 | EPHX2 | 0.751053 | 9 | 0 | 9 |
| RNH1 | PKP3 | 0.750817 | 11 | 0 | 11 |
| RNH1 | TOLLIP | 0.750251 | 12 | 0 | 11 |
| RNH1 | SLC35C1 | 0.749081 | 11 | 0 | 10 |
| RNH1 | IL18 | 0.748865 | 10 | 0 | 10 |
| RNH1 | ENDOU | 0.747715 | 11 | 0 | 11 |
| RNH1 | RNF141 | 0.743809 | 12 | 0 | 12 |
| RNH1 | SERPINB6 | 0.743671 | 11 | 0 | 10 |
| RNH1 | MAPK3 | 0.739964 | 11 | 0 | 11 |
| RNH1 | SPINK7 | 0.739896 | 6 | 0 | 5 |
| RNH1 | COMMD1 | 0.737924 | 4 | 0 | 4 |
| RNH1 | DHRS1 | 0.737702 | 10 | 0 | 9 |
| RNH1 | HECTD1 | 0.736724 | 4 | 0 | 4 |
| RNH1 | DUSP5 | 0.734341 | 10 | 0 | 10 |
| RNH1 | MGLL | 0.729577 | 12 | 0 | 12 |
For details and further investigation, click here
