| Full name: proline rich nuclear receptor coactivator 1 | Alias Symbol: B4-2|PRR2 | ||
| Type: protein-coding gene | Cytoband: 6q15 | ||
| Entrez ID: 10957 | HGNC ID: HGNC:17278 | Ensembl Gene: ENSG00000146278 | OMIM ID: 606714 |
| Drug and gene relationship at DGIdb | |||
Expression of PNRC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PNRC1 | 10957 | 209034_at | -0.5664 | 0.2968 | |
| GSE20347 | PNRC1 | 10957 | 209034_at | -0.2356 | 0.1373 | |
| GSE23400 | PNRC1 | 10957 | 209034_at | -0.0883 | 0.1761 | |
| GSE26886 | PNRC1 | 10957 | 209034_at | 0.3720 | 0.0898 | |
| GSE29001 | PNRC1 | 10957 | 209034_at | -0.2592 | 0.2653 | |
| GSE38129 | PNRC1 | 10957 | 209034_at | -0.4138 | 0.0012 | |
| GSE45670 | PNRC1 | 10957 | 209034_at | -0.2699 | 0.0106 | |
| GSE53622 | PNRC1 | 10957 | 56876 | -0.4657 | 0.0000 | |
| GSE53624 | PNRC1 | 10957 | 56876 | -0.3498 | 0.0000 | |
| GSE63941 | PNRC1 | 10957 | 209034_at | -0.3167 | 0.4181 | |
| GSE77861 | PNRC1 | 10957 | 209034_at | -0.0421 | 0.8255 | |
| GSE97050 | PNRC1 | 10957 | A_33_P3279831 | -0.9556 | 0.1156 | |
| SRP007169 | PNRC1 | 10957 | RNAseq | -0.7302 | 0.0419 | |
| SRP008496 | PNRC1 | 10957 | RNAseq | -0.3313 | 0.1358 | |
| SRP064894 | PNRC1 | 10957 | RNAseq | 0.0426 | 0.8706 | |
| SRP133303 | PNRC1 | 10957 | RNAseq | -0.3735 | 0.0486 | |
| SRP159526 | PNRC1 | 10957 | RNAseq | -0.2144 | 0.2633 | |
| SRP193095 | PNRC1 | 10957 | RNAseq | -0.2693 | 0.0597 | |
| SRP219564 | PNRC1 | 10957 | RNAseq | -0.3340 | 0.5432 | |
| TCGA | PNRC1 | 10957 | RNAseq | -0.1124 | 0.0813 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PNRC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PNRC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PNRC1 | 10957 | 1 | 4 | 25 | |
| GSE20123 | PNRC1 | 10957 | 1 | 3 | 26 | |
| GSE43470 | PNRC1 | 10957 | 3 | 1 | 39 | |
| GSE46452 | PNRC1 | 10957 | 2 | 11 | 46 | |
| GSE47630 | PNRC1 | 10957 | 8 | 6 | 26 | |
| GSE54993 | PNRC1 | 10957 | 3 | 2 | 65 | |
| GSE54994 | PNRC1 | 10957 | 8 | 8 | 37 | |
| GSE60625 | PNRC1 | 10957 | 0 | 1 | 10 | |
| GSE74703 | PNRC1 | 10957 | 3 | 1 | 32 | |
| GSE74704 | PNRC1 | 10957 | 0 | 2 | 18 | |
| TCGA | PNRC1 | 10957 | 8 | 21 | 67 |
Total number of gains: 37; Total number of losses: 60; Total Number of normals: 391.
Somatic mutations of PNRC1:
Generating mutation plots.
Highly correlated genes for PNRC1:
Showing top 20/498 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PNRC1 | DNAJC18 | 0.779986 | 3 | 0 | 3 |
| PNRC1 | C5orf24 | 0.769328 | 3 | 0 | 3 |
| PNRC1 | MIER1 | 0.745927 | 3 | 0 | 3 |
| PNRC1 | AGBL5 | 0.728608 | 3 | 0 | 3 |
| PNRC1 | MCAM | 0.713163 | 3 | 0 | 3 |
| PNRC1 | NOL3 | 0.692844 | 3 | 0 | 3 |
| PNRC1 | TMOD2 | 0.680338 | 4 | 0 | 4 |
| PNRC1 | NT5DC1 | 0.676348 | 3 | 0 | 3 |
| PNRC1 | NR4A1 | 0.675167 | 4 | 0 | 3 |
| PNRC1 | CDS2 | 0.672492 | 3 | 0 | 3 |
| PNRC1 | ZNF34 | 0.671831 | 4 | 0 | 3 |
| PNRC1 | ZMAT1 | 0.666068 | 5 | 0 | 4 |
| PNRC1 | RABAC1 | 0.664386 | 3 | 0 | 3 |
| PNRC1 | SKP1 | 0.659765 | 5 | 0 | 4 |
| PNRC1 | RFXAP | 0.658825 | 3 | 0 | 3 |
| PNRC1 | CCDC92 | 0.658594 | 4 | 0 | 3 |
| PNRC1 | PDCD4 | 0.658006 | 3 | 0 | 3 |
| PNRC1 | CACNA2D2 | 0.657769 | 4 | 0 | 3 |
| PNRC1 | CLDND2 | 0.657253 | 3 | 0 | 3 |
| PNRC1 | UST | 0.646602 | 3 | 0 | 3 |
For details and further investigation, click here
