| Full name: CDP-diacylglycerol synthase 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20p12.3 | ||
| Entrez ID: 8760 | HGNC ID: HGNC:1801 | Ensembl Gene: ENSG00000101290 | OMIM ID: 603549 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CDS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDS2 | 8760 | 228456_s_at | -0.2099 | 0.8462 | |
| GSE20347 | CDS2 | 8760 | 212862_at | 0.4100 | 0.0336 | |
| GSE23400 | CDS2 | 8760 | 212862_at | 0.3111 | 0.0000 | |
| GSE26886 | CDS2 | 8760 | 228456_s_at | 0.3531 | 0.2378 | |
| GSE29001 | CDS2 | 8760 | 212864_at | 0.4221 | 0.0961 | |
| GSE38129 | CDS2 | 8760 | 212862_at | 0.4594 | 0.0096 | |
| GSE45670 | CDS2 | 8760 | 212862_at | 0.3645 | 0.0104 | |
| GSE53622 | CDS2 | 8760 | 59409 | -0.2589 | 0.0110 | |
| GSE53624 | CDS2 | 8760 | 59409 | 0.3730 | 0.0000 | |
| GSE63941 | CDS2 | 8760 | 212862_at | -0.5221 | 0.2440 | |
| GSE77861 | CDS2 | 8760 | 228456_s_at | 0.2182 | 0.3270 | |
| GSE97050 | CDS2 | 8760 | A_24_P271363 | -0.8728 | 0.1726 | |
| SRP007169 | CDS2 | 8760 | RNAseq | 0.5201 | 0.1716 | |
| SRP008496 | CDS2 | 8760 | RNAseq | 0.9451 | 0.0002 | |
| SRP064894 | CDS2 | 8760 | RNAseq | 0.3905 | 0.0070 | |
| SRP133303 | CDS2 | 8760 | RNAseq | -0.1354 | 0.5092 | |
| SRP159526 | CDS2 | 8760 | RNAseq | 0.1154 | 0.5769 | |
| SRP193095 | CDS2 | 8760 | RNAseq | 0.1753 | 0.0829 | |
| SRP219564 | CDS2 | 8760 | RNAseq | -0.1742 | 0.7270 | |
| TCGA | CDS2 | 8760 | RNAseq | -0.1204 | 0.0179 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CDS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDS2 | 8760 | 10 | 3 | 17 | |
| GSE20123 | CDS2 | 8760 | 10 | 3 | 17 | |
| GSE43470 | CDS2 | 8760 | 10 | 1 | 32 | |
| GSE46452 | CDS2 | 8760 | 26 | 1 | 32 | |
| GSE47630 | CDS2 | 8760 | 18 | 4 | 18 | |
| GSE54993 | CDS2 | 8760 | 2 | 14 | 54 | |
| GSE54994 | CDS2 | 8760 | 25 | 2 | 26 | |
| GSE60625 | CDS2 | 8760 | 0 | 0 | 11 | |
| GSE74703 | CDS2 | 8760 | 9 | 1 | 26 | |
| GSE74704 | CDS2 | 8760 | 5 | 1 | 14 | |
| TCGA | CDS2 | 8760 | 40 | 11 | 45 |
Total number of gains: 155; Total number of losses: 41; Total Number of normals: 292.
Somatic mutations of CDS2:
Generating mutation plots.
Highly correlated genes for CDS2:
Showing top 20/666 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDS2 | FNIP2 | 0.781284 | 3 | 0 | 3 |
| CDS2 | RGMB | 0.77902 | 3 | 0 | 3 |
| CDS2 | CFL2 | 0.767 | 3 | 0 | 3 |
| CDS2 | SGTB | 0.764295 | 3 | 0 | 3 |
| CDS2 | GPM6B | 0.754641 | 3 | 0 | 3 |
| CDS2 | SP4 | 0.754001 | 4 | 0 | 4 |
| CDS2 | IGIP | 0.751951 | 3 | 0 | 3 |
| CDS2 | IGFBP6 | 0.751174 | 3 | 0 | 3 |
| CDS2 | FAM13B | 0.749334 | 3 | 0 | 3 |
| CDS2 | C5orf24 | 0.733411 | 3 | 0 | 3 |
| CDS2 | KIAA0753 | 0.733218 | 3 | 0 | 3 |
| CDS2 | PAMR1 | 0.72924 | 3 | 0 | 3 |
| CDS2 | ROCK1 | 0.726407 | 4 | 0 | 4 |
| CDS2 | CYP2U1 | 0.725655 | 3 | 0 | 3 |
| CDS2 | CACNB2 | 0.72434 | 3 | 0 | 3 |
| CDS2 | PURA | 0.722019 | 3 | 0 | 3 |
| CDS2 | DOCK11 | 0.720718 | 3 | 0 | 3 |
| CDS2 | RAB6B | 0.720047 | 3 | 0 | 3 |
| CDS2 | ACAA2 | 0.715704 | 3 | 0 | 3 |
| CDS2 | ANO5 | 0.7143 | 3 | 0 | 3 |
For details and further investigation, click here
