| Full name: uronyl 2-sulfotransferase | Alias Symbol: 2OST | ||
| Type: protein-coding gene | Cytoband: 6q25.1 | ||
| Entrez ID: 10090 | HGNC ID: HGNC:17223 | Ensembl Gene: ENSG00000111962 | OMIM ID: 610752 |
| Drug and gene relationship at DGIdb | |||
Expression of UST:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UST | 10090 | 205139_s_at | 0.3649 | 0.7018 | |
| GSE20347 | UST | 10090 | 205139_s_at | 0.7696 | 0.0027 | |
| GSE23400 | UST | 10090 | 205139_s_at | 0.2707 | 0.0027 | |
| GSE26886 | UST | 10090 | 205139_s_at | 0.6581 | 0.1064 | |
| GSE29001 | UST | 10090 | 205139_s_at | 0.7045 | 0.1030 | |
| GSE38129 | UST | 10090 | 205139_s_at | 0.4968 | 0.1345 | |
| GSE45670 | UST | 10090 | 205139_s_at | -0.0740 | 0.8929 | |
| GSE53622 | UST | 10090 | 51270 | 0.3183 | 0.0261 | |
| GSE53624 | UST | 10090 | 51270 | 0.4215 | 0.0012 | |
| GSE63941 | UST | 10090 | 205139_s_at | -2.1196 | 0.1141 | |
| GSE77861 | UST | 10090 | 205139_s_at | 1.1028 | 0.0023 | |
| GSE97050 | UST | 10090 | A_23_P314145 | -0.3522 | 0.4926 | |
| SRP007169 | UST | 10090 | RNAseq | 2.3740 | 0.0002 | |
| SRP008496 | UST | 10090 | RNAseq | 2.8625 | 0.0000 | |
| SRP064894 | UST | 10090 | RNAseq | 0.1079 | 0.6950 | |
| SRP133303 | UST | 10090 | RNAseq | 0.6600 | 0.0028 | |
| SRP159526 | UST | 10090 | RNAseq | 1.4044 | 0.0057 | |
| SRP193095 | UST | 10090 | RNAseq | 0.3253 | 0.0329 | |
| SRP219564 | UST | 10090 | RNAseq | 0.2504 | 0.5869 | |
| TCGA | UST | 10090 | RNAseq | -0.0091 | 0.9406 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by UST expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UST:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UST | 10090 | 2 | 4 | 24 | |
| GSE20123 | UST | 10090 | 2 | 3 | 25 | |
| GSE43470 | UST | 10090 | 4 | 0 | 39 | |
| GSE46452 | UST | 10090 | 3 | 10 | 46 | |
| GSE47630 | UST | 10090 | 9 | 4 | 27 | |
| GSE54993 | UST | 10090 | 3 | 2 | 65 | |
| GSE54994 | UST | 10090 | 8 | 8 | 37 | |
| GSE60625 | UST | 10090 | 0 | 1 | 10 | |
| GSE74703 | UST | 10090 | 4 | 0 | 32 | |
| GSE74704 | UST | 10090 | 1 | 1 | 18 | |
| TCGA | UST | 10090 | 11 | 22 | 63 |
Total number of gains: 47; Total number of losses: 55; Total Number of normals: 386.
Somatic mutations of UST:
Generating mutation plots.
Highly correlated genes for UST:
Showing top 20/513 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UST | FOXP2 | 0.74152 | 3 | 0 | 3 |
| UST | RBM24 | 0.735101 | 3 | 0 | 3 |
| UST | ANKRD23 | 0.692094 | 4 | 0 | 4 |
| UST | ITPK1 | 0.688872 | 3 | 0 | 3 |
| UST | HSPA12A | 0.679036 | 4 | 0 | 4 |
| UST | MYOT | 0.677228 | 3 | 0 | 3 |
| UST | MSI2 | 0.676537 | 4 | 0 | 4 |
| UST | MRPS26 | 0.676364 | 3 | 0 | 3 |
| UST | SLC12A2 | 0.675656 | 3 | 0 | 3 |
| UST | RILPL1 | 0.671441 | 3 | 0 | 3 |
| UST | KANSL3 | 0.667848 | 5 | 0 | 5 |
| UST | SH3BGR | 0.662779 | 3 | 0 | 3 |
| UST | GNA11 | 0.661634 | 3 | 0 | 3 |
| UST | PELI3 | 0.660087 | 3 | 0 | 3 |
| UST | DPY19L2 | 0.659146 | 3 | 0 | 3 |
| UST | NT5C3B | 0.659048 | 3 | 0 | 3 |
| UST | TBL1X | 0.658589 | 4 | 0 | 4 |
| UST | MAOA | 0.65588 | 3 | 0 | 3 |
| UST | HCFC1R1 | 0.654785 | 4 | 0 | 3 |
| UST | TBC1D31 | 0.652923 | 4 | 0 | 3 |
For details and further investigation, click here
