| Full name: 5'-nucleotidase domain containing 1 | Alias Symbol: dJ486I3.1|MGC24302 | ||
| Type: protein-coding gene | Cytoband: 6q22.1 | ||
| Entrez ID: 221294 | HGNC ID: HGNC:21556 | Ensembl Gene: ENSG00000178425 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NT5DC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NT5DC1 | 221294 | 223177_at | -0.4477 | 0.3964 | |
| GSE26886 | NT5DC1 | 221294 | 223178_s_at | -0.6331 | 0.0582 | |
| GSE45670 | NT5DC1 | 221294 | 223177_at | -0.1496 | 0.2688 | |
| GSE53622 | NT5DC1 | 221294 | 6142 | -0.0913 | 0.1926 | |
| GSE53624 | NT5DC1 | 221294 | 6142 | -0.2720 | 0.0062 | |
| GSE63941 | NT5DC1 | 221294 | 223177_at | -0.8869 | 0.0698 | |
| GSE77861 | NT5DC1 | 221294 | 223177_at | 0.0316 | 0.9164 | |
| GSE97050 | NT5DC1 | 221294 | A_23_P382043 | -0.3120 | 0.3811 | |
| SRP007169 | NT5DC1 | 221294 | RNAseq | -0.2045 | 0.6296 | |
| SRP008496 | NT5DC1 | 221294 | RNAseq | -0.3509 | 0.1871 | |
| SRP064894 | NT5DC1 | 221294 | RNAseq | -0.3225 | 0.0526 | |
| SRP133303 | NT5DC1 | 221294 | RNAseq | -0.1725 | 0.0711 | |
| SRP159526 | NT5DC1 | 221294 | RNAseq | -0.3865 | 0.1203 | |
| SRP193095 | NT5DC1 | 221294 | RNAseq | -0.4399 | 0.0001 | |
| SRP219564 | NT5DC1 | 221294 | RNAseq | -0.3931 | 0.1040 | |
| TCGA | NT5DC1 | 221294 | RNAseq | -0.2185 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NT5DC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NT5DC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NT5DC1 | 221294 | 1 | 4 | 25 | |
| GSE20123 | NT5DC1 | 221294 | 1 | 3 | 26 | |
| GSE43470 | NT5DC1 | 221294 | 3 | 1 | 39 | |
| GSE46452 | NT5DC1 | 221294 | 2 | 11 | 46 | |
| GSE47630 | NT5DC1 | 221294 | 9 | 4 | 27 | |
| GSE54993 | NT5DC1 | 221294 | 3 | 2 | 65 | |
| GSE54994 | NT5DC1 | 221294 | 8 | 8 | 37 | |
| GSE60625 | NT5DC1 | 221294 | 0 | 2 | 9 | |
| GSE74703 | NT5DC1 | 221294 | 2 | 1 | 33 | |
| GSE74704 | NT5DC1 | 221294 | 0 | 1 | 19 | |
| TCGA | NT5DC1 | 221294 | 6 | 23 | 67 |
Total number of gains: 35; Total number of losses: 60; Total Number of normals: 393.
Somatic mutations of NT5DC1:
Generating mutation plots.
Highly correlated genes for NT5DC1:
Showing top 20/112 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NT5DC1 | COQ9 | 0.719572 | 3 | 0 | 3 |
| NT5DC1 | LYPLAL1 | 0.680117 | 3 | 0 | 3 |
| NT5DC1 | PNRC1 | 0.676348 | 3 | 0 | 3 |
| NT5DC1 | MTFMT | 0.660173 | 3 | 0 | 3 |
| NT5DC1 | ARL6IP5 | 0.656164 | 3 | 0 | 3 |
| NT5DC1 | GSN | 0.655875 | 3 | 0 | 3 |
| NT5DC1 | EIF2B4 | 0.654386 | 3 | 0 | 3 |
| NT5DC1 | NSRP1 | 0.644034 | 4 | 0 | 3 |
| NT5DC1 | MRPL46 | 0.642901 | 4 | 0 | 3 |
| NT5DC1 | ANKRD6 | 0.636082 | 3 | 0 | 3 |
| NT5DC1 | FH | 0.629319 | 3 | 0 | 3 |
| NT5DC1 | IK | 0.628075 | 3 | 0 | 3 |
| NT5DC1 | IFT46 | 0.624555 | 3 | 0 | 3 |
| NT5DC1 | MTRF1L | 0.620531 | 4 | 0 | 3 |
| NT5DC1 | ANKRA2 | 0.620103 | 4 | 0 | 3 |
| NT5DC1 | MOCS2 | 0.61619 | 4 | 0 | 3 |
| NT5DC1 | TCF21 | 0.612574 | 3 | 0 | 3 |
| NT5DC1 | MFSD6 | 0.611947 | 4 | 0 | 4 |
| NT5DC1 | HOXA3 | 0.611421 | 4 | 0 | 3 |
| NT5DC1 | TMEM98 | 0.610845 | 5 | 0 | 4 |
For details and further investigation, click here
