| Full name: MIER1 transcriptional regulator | Alias Symbol: hMI-ER1|MI-ER1|KIAA1610 | ||
| Type: protein-coding gene | Cytoband: 1p31.3 | ||
| Entrez ID: 57708 | HGNC ID: HGNC:29657 | Ensembl Gene: ENSG00000198160 | OMIM ID: 616848 |
| Drug and gene relationship at DGIdb | |||
Expression of MIER1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MIER1 | 57708 | 225475_at | -0.2575 | 0.3079 | |
| GSE26886 | MIER1 | 57708 | 225475_at | -0.1728 | 0.4183 | |
| GSE45670 | MIER1 | 57708 | 225475_at | -0.2992 | 0.0205 | |
| GSE53622 | MIER1 | 57708 | 17684 | -0.3115 | 0.0000 | |
| GSE53624 | MIER1 | 57708 | 17684 | -0.0537 | 0.3290 | |
| GSE63941 | MIER1 | 57708 | 225475_at | -0.1994 | 0.7175 | |
| GSE77861 | MIER1 | 57708 | 225475_at | -0.2193 | 0.4163 | |
| GSE97050 | MIER1 | 57708 | A_24_P230916 | -0.5865 | 0.1246 | |
| SRP007169 | MIER1 | 57708 | RNAseq | 0.4466 | 0.1938 | |
| SRP008496 | MIER1 | 57708 | RNAseq | 0.8854 | 0.0002 | |
| SRP064894 | MIER1 | 57708 | RNAseq | -0.0091 | 0.9555 | |
| SRP133303 | MIER1 | 57708 | RNAseq | 0.2018 | 0.1883 | |
| SRP159526 | MIER1 | 57708 | RNAseq | -0.6285 | 0.0348 | |
| SRP193095 | MIER1 | 57708 | RNAseq | -0.3121 | 0.0014 | |
| SRP219564 | MIER1 | 57708 | RNAseq | 0.0402 | 0.8986 | |
| TCGA | MIER1 | 57708 | RNAseq | -0.0942 | 0.0397 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MIER1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MIER1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MIER1 | 57708 | 1 | 6 | 23 | |
| GSE20123 | MIER1 | 57708 | 1 | 5 | 24 | |
| GSE43470 | MIER1 | 57708 | 5 | 2 | 36 | |
| GSE46452 | MIER1 | 57708 | 0 | 1 | 58 | |
| GSE47630 | MIER1 | 57708 | 8 | 5 | 27 | |
| GSE54993 | MIER1 | 57708 | 0 | 0 | 70 | |
| GSE54994 | MIER1 | 57708 | 6 | 4 | 43 | |
| GSE60625 | MIER1 | 57708 | 0 | 0 | 11 | |
| GSE74703 | MIER1 | 57708 | 4 | 2 | 30 | |
| GSE74704 | MIER1 | 57708 | 1 | 2 | 17 | |
| TCGA | MIER1 | 57708 | 9 | 22 | 65 |
Total number of gains: 35; Total number of losses: 49; Total Number of normals: 404.
Somatic mutations of MIER1:
Generating mutation plots.
Highly correlated genes for MIER1:
Showing top 20/449 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MIER1 | ITPR1 | 0.797547 | 3 | 0 | 3 |
| MIER1 | CNRIP1 | 0.791194 | 3 | 0 | 3 |
| MIER1 | GNG11 | 0.78675 | 3 | 0 | 3 |
| MIER1 | SATB1 | 0.785241 | 3 | 0 | 3 |
| MIER1 | ACO1 | 0.774353 | 3 | 0 | 3 |
| MIER1 | EDNRB | 0.774166 | 3 | 0 | 3 |
| MIER1 | COX7A1 | 0.773039 | 3 | 0 | 3 |
| MIER1 | PNRC1 | 0.745927 | 3 | 0 | 3 |
| MIER1 | GNPDA2 | 0.742587 | 3 | 0 | 3 |
| MIER1 | PTPRB | 0.737217 | 3 | 0 | 3 |
| MIER1 | DNALI1 | 0.732724 | 3 | 0 | 3 |
| MIER1 | KLHDC8B | 0.728745 | 3 | 0 | 3 |
| MIER1 | GPRC5B | 0.72863 | 3 | 0 | 3 |
| MIER1 | ZCCHC24 | 0.725881 | 4 | 0 | 3 |
| MIER1 | RHOT1 | 0.724298 | 3 | 0 | 3 |
| MIER1 | SOBP | 0.723368 | 3 | 0 | 3 |
| MIER1 | PRKG1 | 0.722333 | 3 | 0 | 3 |
| MIER1 | TSPYL1 | 0.719737 | 3 | 0 | 3 |
| MIER1 | PRKACB | 0.719601 | 4 | 0 | 3 |
| MIER1 | SERINC1 | 0.718341 | 5 | 0 | 5 |
For details and further investigation, click here
