| Full name: nuclear receptor subfamily 5 group A member 1 | Alias Symbol: FTZ1|SF-1|ELP|AD4BP|hSF-1|SF1 | ||
| Type: protein-coding gene | Cytoband: 9q33.3 | ||
| Entrez ID: 2516 | HGNC ID: HGNC:7983 | Ensembl Gene: ENSG00000136931 | OMIM ID: 184757 |
| Drug and gene relationship at DGIdb | |||
Expression of NR5A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NR5A1 | 2516 | 210333_at | -0.1513 | 0.4900 | |
| GSE20347 | NR5A1 | 2516 | 210333_at | -0.1239 | 0.1659 | |
| GSE23400 | NR5A1 | 2516 | 210333_at | -0.2700 | 0.0000 | |
| GSE26886 | NR5A1 | 2516 | 210333_at | 0.3179 | 0.0151 | |
| GSE29001 | NR5A1 | 2516 | 210333_at | 0.0019 | 0.9925 | |
| GSE38129 | NR5A1 | 2516 | 210333_at | -0.1496 | 0.1355 | |
| GSE45670 | NR5A1 | 2516 | 210333_at | -0.1324 | 0.1029 | |
| GSE53622 | NR5A1 | 2516 | 42856 | 0.5085 | 0.0437 | |
| GSE53624 | NR5A1 | 2516 | 42856 | 0.1019 | 0.4825 | |
| GSE63941 | NR5A1 | 2516 | 210333_at | 0.0495 | 0.8183 | |
| GSE77861 | NR5A1 | 2516 | 210333_at | -0.1775 | 0.1154 | |
| TCGA | NR5A1 | 2516 | RNAseq | 4.3158 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NR5A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NR5A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NR5A1 | 2516 | 4 | 8 | 18 | |
| GSE20123 | NR5A1 | 2516 | 4 | 8 | 18 | |
| GSE43470 | NR5A1 | 2516 | 6 | 4 | 33 | |
| GSE46452 | NR5A1 | 2516 | 6 | 13 | 40 | |
| GSE47630 | NR5A1 | 2516 | 3 | 16 | 21 | |
| GSE54993 | NR5A1 | 2516 | 3 | 3 | 64 | |
| GSE54994 | NR5A1 | 2516 | 9 | 10 | 34 | |
| GSE60625 | NR5A1 | 2516 | 0 | 0 | 11 | |
| GSE74703 | NR5A1 | 2516 | 5 | 3 | 28 | |
| GSE74704 | NR5A1 | 2516 | 2 | 6 | 12 | |
| TCGA | NR5A1 | 2516 | 27 | 25 | 44 |
Total number of gains: 69; Total number of losses: 96; Total Number of normals: 323.
Somatic mutations of NR5A1:
Generating mutation plots.
Highly correlated genes for NR5A1:
Showing top 20/833 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NR5A1 | NCR2 | 0.71107 | 5 | 0 | 5 |
| NR5A1 | PHLDB1 | 0.70388 | 5 | 0 | 5 |
| NR5A1 | ANKRD1 | 0.701328 | 3 | 0 | 3 |
| NR5A1 | ACVRL1 | 0.690687 | 3 | 0 | 3 |
| NR5A1 | CLDN11 | 0.685067 | 5 | 0 | 4 |
| NR5A1 | PCBP4 | 0.683048 | 3 | 0 | 3 |
| NR5A1 | HOXA3 | 0.682164 | 4 | 0 | 4 |
| NR5A1 | EDA2R | 0.68095 | 4 | 0 | 4 |
| NR5A1 | CHRNA6 | 0.678497 | 5 | 0 | 4 |
| NR5A1 | ADRB3 | 0.677885 | 3 | 0 | 3 |
| NR5A1 | POU3F1 | 0.676979 | 3 | 0 | 3 |
| NR5A1 | IFNA21 | 0.675653 | 5 | 0 | 5 |
| NR5A1 | CCDC7 | 0.675439 | 4 | 0 | 4 |
| NR5A1 | RHAG | 0.67146 | 5 | 0 | 5 |
| NR5A1 | TMPRSS15 | 0.671269 | 6 | 0 | 6 |
| NR5A1 | P2RX6 | 0.669006 | 5 | 0 | 5 |
| NR5A1 | TMEM151B | 0.669005 | 6 | 0 | 6 |
| NR5A1 | CCR9 | 0.667926 | 5 | 0 | 5 |
| NR5A1 | SSTR4 | 0.667277 | 6 | 0 | 5 |
| NR5A1 | ERN1 | 0.667258 | 3 | 0 | 3 |
For details and further investigation, click here
