GML

 

Full name: glycosylphosphatidylinositol anchored molecule like Alias Symbol: LY6DL
Type: protein-coding gene Cytoband: 8q24.3
Entrez ID: 2765 HGNC ID: HGNC:4375 Ensembl Gene: ENSG00000104499 OMIM ID: 602370
Drug and gene relationship at DGIdb

 

Expression of GML:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GML 2765 208000_at -0.0194 0.9602
GSE20347 GML 2765 208000_at 0.0427 0.6004
GSE23400 GML 2765 208000_at -0.1116 0.0360
GSE26886 GML 2765 208000_at -0.0885 0.5690
GSE29001 GML 2765 208000_at -0.2082 0.3049
GSE38129 GML 2765 208000_at -0.0795 0.4504
GSE45670 GML 2765 208000_at 0.0785 0.3840
GSE53622 GML 2765 30954 -0.0011 0.9891
GSE53624 GML 2765 30954 -0.1615 0.0208
GSE63941 GML 2765 208000_at 0.2720 0.0378
GSE77861 GML 2765 208000_at -0.1768 0.3489

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by GML expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GML:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GML 2765 16 1 13
GSE20123 GML 2765 17 1 12
GSE43470 GML 2765 17 2 24
GSE46452 GML 2765 27 0 32
GSE47630 GML 2765 23 1 16
GSE54993 GML 2765 0 25 45
GSE54994 GML 2765 39 1 13
GSE60625 GML 2765 3 4 4
GSE74703 GML 2765 15 1 20
GSE74704 GML 2765 10 0 10
TCGA GML 2765 64 2 30

Total number of gains: 231; Total number of losses: 38; Total Number of normals: 219.  


 

Somatic mutations of GML:

 

Generating mutation plots.

 

Highly correlated genes for GML:

 

Showing top 20/1024 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GMLCBL0.778255404
GMLCIITA0.759344505
GMLIL1RAPL20.758219606
GMLKHDRBS20.756739505
GMLECE20.739544404
GMLACSBG20.731249606
GMLCC2D2B0.728365303
GMLLUZP40.727677606
GMLFCGR2C0.718672303
GMLTRPM30.718413505
GMLNEUROD20.71775505
GMLPKD2L20.716106303
GMLFABP10.715896303
GMLLBP0.710617505
GMLDPF30.704516505
GMLIL210.703485505
GMLRSPH6A0.703358404
GMLCYP1A20.702407505
GMLOPRM10.701208606
GMLCCDC70.700912404

For details and further investigation, click here