| Full name: homeobox D11 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q31.1 | ||
| Entrez ID: 3237 | HGNC ID: HGNC:5134 | Ensembl Gene: ENSG00000128713 | OMIM ID: 142986 |
| Drug and gene relationship at DGIdb | |||
Expression of HOXD11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXD11 | 3237 | 214604_at | 2.6380 | 0.0411 | |
| GSE20347 | HOXD11 | 3237 | 214604_at | 1.2404 | 0.0000 | |
| GSE23400 | HOXD11 | 3237 | 214604_at | 0.7314 | 0.0000 | |
| GSE26886 | HOXD11 | 3237 | 214604_at | 1.4743 | 0.0000 | |
| GSE29001 | HOXD11 | 3237 | 214604_at | 2.6679 | 0.0000 | |
| GSE38129 | HOXD11 | 3237 | 214604_at | 1.7320 | 0.0000 | |
| GSE45670 | HOXD11 | 3237 | 214604_at | 1.8666 | 0.0000 | |
| GSE53622 | HOXD11 | 3237 | 23379 | 5.1302 | 0.0000 | |
| GSE53624 | HOXD11 | 3237 | 23379 | 3.9987 | 0.0000 | |
| GSE63941 | HOXD11 | 3237 | 214604_at | 2.6123 | 0.0066 | |
| GSE77861 | HOXD11 | 3237 | 214604_at | 0.7094 | 0.0682 | |
| GSE97050 | HOXD11 | 3237 | A_23_P143029 | 2.8816 | 0.0976 | |
| SRP007169 | HOXD11 | 3237 | RNAseq | 7.4664 | 0.0000 | |
| SRP133303 | HOXD11 | 3237 | RNAseq | 4.2354 | 0.0000 | |
| SRP159526 | HOXD11 | 3237 | RNAseq | 6.7633 | 0.0000 | |
| TCGA | HOXD11 | 3237 | RNAseq | 3.0713 | 0.0000 |
Upregulated datasets: 13; Downregulated datasets: 0.
Survival by HOXD11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HOXD11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXD11 | 3237 | 9 | 0 | 21 | |
| GSE20123 | HOXD11 | 3237 | 9 | 0 | 21 | |
| GSE43470 | HOXD11 | 3237 | 5 | 1 | 37 | |
| GSE46452 | HOXD11 | 3237 | 1 | 4 | 54 | |
| GSE47630 | HOXD11 | 3237 | 4 | 4 | 32 | |
| GSE54993 | HOXD11 | 3237 | 0 | 5 | 65 | |
| GSE54994 | HOXD11 | 3237 | 11 | 4 | 38 | |
| GSE60625 | HOXD11 | 3237 | 0 | 3 | 8 | |
| GSE74703 | HOXD11 | 3237 | 4 | 1 | 31 | |
| GSE74704 | HOXD11 | 3237 | 5 | 0 | 15 | |
| TCGA | HOXD11 | 3237 | 28 | 5 | 63 |
Total number of gains: 76; Total number of losses: 27; Total Number of normals: 385.
Somatic mutations of HOXD11:
Generating mutation plots.
Highly correlated genes for HOXD11:
Showing top 20/1700 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXD11 | HOXD10 | 0.852956 | 13 | 0 | 13 |
| HOXD11 | TTYH3 | 0.779942 | 7 | 0 | 7 |
| HOXD11 | CMSS1 | 0.772573 | 6 | 0 | 6 |
| HOXD11 | WDR66 | 0.769772 | 8 | 0 | 8 |
| HOXD11 | SNAI2 | 0.760881 | 7 | 0 | 7 |
| HOXD11 | COL27A1 | 0.75631 | 6 | 0 | 6 |
| HOXD11 | MMP1 | 0.750743 | 11 | 0 | 11 |
| HOXD11 | FSCN1 | 0.748383 | 12 | 0 | 12 |
| HOXD11 | AURKA | 0.746403 | 10 | 0 | 10 |
| HOXD11 | MCM4 | 0.745855 | 11 | 0 | 10 |
| HOXD11 | MYBL2 | 0.745481 | 12 | 0 | 12 |
| HOXD11 | PLAU | 0.738338 | 11 | 0 | 11 |
| HOXD11 | TRIP13 | 0.737766 | 11 | 0 | 11 |
| HOXD11 | MFAP2 | 0.737077 | 11 | 0 | 11 |
| HOXD11 | LRRC8D | 0.736131 | 11 | 0 | 10 |
| HOXD11 | SALL4 | 0.733976 | 7 | 0 | 7 |
| HOXD11 | CENPF | 0.733404 | 10 | 0 | 10 |
| HOXD11 | PTK7 | 0.732248 | 11 | 0 | 11 |
| HOXD11 | HOXB7 | 0.731212 | 12 | 0 | 12 |
| HOXD11 | ALKBH6 | 0.729857 | 4 | 0 | 4 |
For details and further investigation, click here
