| Full name: transmembrane 4 L six family member 4 | Alias Symbol: il-TMP | ||
| Type: protein-coding gene | Cytoband: 3q25.1 | ||
| Entrez ID: 7104 | HGNC ID: HGNC:11856 | Ensembl Gene: ENSG00000169903 | OMIM ID: 606567 |
| Drug and gene relationship at DGIdb | |||
Expression of TM4SF4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TM4SF4 | 7104 | 209937_at | -0.0923 | 0.7511 | |
| GSE20347 | TM4SF4 | 7104 | 209937_at | 0.1193 | 0.1441 | |
| GSE23400 | TM4SF4 | 7104 | 209937_at | -0.0208 | 0.5683 | |
| GSE26886 | TM4SF4 | 7104 | 209937_at | -0.1865 | 0.0963 | |
| GSE29001 | TM4SF4 | 7104 | 209937_at | -0.3027 | 0.0664 | |
| GSE38129 | TM4SF4 | 7104 | 209937_at | -0.2689 | 0.0793 | |
| GSE45670 | TM4SF4 | 7104 | 209937_at | -0.0762 | 0.3672 | |
| GSE53622 | TM4SF4 | 7104 | 165266 | -0.9502 | 0.0000 | |
| GSE53624 | TM4SF4 | 7104 | 165266 | -1.4780 | 0.0000 | |
| GSE63941 | TM4SF4 | 7104 | 209937_at | 0.1704 | 0.3330 | |
| GSE77861 | TM4SF4 | 7104 | 209937_at | -0.0178 | 0.8904 | |
| TCGA | TM4SF4 | 7104 | RNAseq | -4.0553 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TM4SF4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TM4SF4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TM4SF4 | 7104 | 22 | 0 | 8 | |
| GSE20123 | TM4SF4 | 7104 | 22 | 0 | 8 | |
| GSE43470 | TM4SF4 | 7104 | 23 | 0 | 20 | |
| GSE46452 | TM4SF4 | 7104 | 18 | 2 | 39 | |
| GSE47630 | TM4SF4 | 7104 | 19 | 3 | 18 | |
| GSE54993 | TM4SF4 | 7104 | 1 | 10 | 59 | |
| GSE54994 | TM4SF4 | 7104 | 37 | 1 | 15 | |
| GSE60625 | TM4SF4 | 7104 | 0 | 6 | 5 | |
| GSE74703 | TM4SF4 | 7104 | 20 | 0 | 16 | |
| GSE74704 | TM4SF4 | 7104 | 15 | 0 | 5 | |
| TCGA | TM4SF4 | 7104 | 71 | 1 | 24 |
Total number of gains: 248; Total number of losses: 23; Total Number of normals: 217.
Somatic mutations of TM4SF4:
Generating mutation plots.
Highly correlated genes for TM4SF4:
Showing top 20/594 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TM4SF4 | NEUROD2 | 0.716954 | 3 | 0 | 3 |
| TM4SF4 | LINC01361 | 0.689096 | 3 | 0 | 3 |
| TM4SF4 | TESPA1 | 0.688256 | 3 | 0 | 3 |
| TM4SF4 | NEUROD6 | 0.68525 | 6 | 0 | 6 |
| TM4SF4 | FBP2 | 0.682518 | 5 | 0 | 4 |
| TM4SF4 | MYL1 | 0.68069 | 4 | 0 | 3 |
| TM4SF4 | LHPP | 0.677377 | 3 | 0 | 3 |
| TM4SF4 | GSX1 | 0.67496 | 3 | 0 | 3 |
| TM4SF4 | ITGB3 | 0.673147 | 4 | 0 | 3 |
| TM4SF4 | CELA3A | 0.668815 | 3 | 0 | 3 |
| TM4SF4 | REG3A | 0.667595 | 6 | 0 | 5 |
| TM4SF4 | POU3F1 | 0.660706 | 3 | 0 | 3 |
| TM4SF4 | LINC01339 | 0.660675 | 3 | 0 | 3 |
| TM4SF4 | PPP1R15A | 0.660212 | 4 | 0 | 3 |
| TM4SF4 | PPP1R14D | 0.658415 | 4 | 0 | 4 |
| TM4SF4 | FLRT1 | 0.654784 | 5 | 0 | 5 |
| TM4SF4 | PRKG2 | 0.651569 | 4 | 0 | 4 |
| TM4SF4 | CLDN18 | 0.651287 | 5 | 0 | 4 |
| TM4SF4 | STXBP5L | 0.649938 | 4 | 0 | 3 |
| TM4SF4 | NOX1 | 0.648021 | 5 | 0 | 4 |
For details and further investigation, click here
