| Full name: CD226 molecule | Alias Symbol: DNAM-1|DNAM1|PTA1|TLiSA1 | ||
| Type: protein-coding gene | Cytoband: 18q22.2 | ||
| Entrez ID: 10666 | HGNC ID: HGNC:16961 | Ensembl Gene: ENSG00000150637 | OMIM ID: 605397 |
| Drug and gene relationship at DGIdb | |||
Expression of CD226:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD226 | 10666 | 207315_at | 0.0103 | 0.9768 | |
| GSE20347 | CD226 | 10666 | 207315_at | 0.0297 | 0.6209 | |
| GSE23400 | CD226 | 10666 | 207315_at | -0.0356 | 0.1142 | |
| GSE26886 | CD226 | 10666 | 207315_at | -0.1703 | 0.2517 | |
| GSE29001 | CD226 | 10666 | 207315_at | -0.0060 | 0.9679 | |
| GSE38129 | CD226 | 10666 | 207315_at | -0.0356 | 0.5666 | |
| GSE45670 | CD226 | 10666 | 207315_at | 0.0524 | 0.6339 | |
| GSE53622 | CD226 | 10666 | 45876 | -0.3305 | 0.0472 | |
| GSE53624 | CD226 | 10666 | 45876 | -0.1894 | 0.3682 | |
| GSE63941 | CD226 | 10666 | 207315_at | 0.0210 | 0.8887 | |
| GSE77861 | CD226 | 10666 | 207315_at | -0.1647 | 0.1009 | |
| GSE97050 | CD226 | 10666 | A_33_P3413558 | 0.1828 | 0.5261 | |
| SRP007169 | CD226 | 10666 | RNAseq | 0.1075 | 0.8778 | |
| SRP064894 | CD226 | 10666 | RNAseq | 0.1790 | 0.4913 | |
| SRP133303 | CD226 | 10666 | RNAseq | -0.3163 | 0.1017 | |
| SRP159526 | CD226 | 10666 | RNAseq | -0.6036 | 0.3807 | |
| SRP193095 | CD226 | 10666 | RNAseq | -0.3011 | 0.0279 | |
| SRP219564 | CD226 | 10666 | RNAseq | 0.0341 | 0.9344 | |
| TCGA | CD226 | 10666 | RNAseq | -0.1744 | 0.5508 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CD226 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD226:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD226 | 10666 | 0 | 10 | 20 | |
| GSE20123 | CD226 | 10666 | 0 | 10 | 20 | |
| GSE43470 | CD226 | 10666 | 0 | 8 | 35 | |
| GSE46452 | CD226 | 10666 | 1 | 26 | 32 | |
| GSE47630 | CD226 | 10666 | 5 | 21 | 14 | |
| GSE54993 | CD226 | 10666 | 9 | 0 | 61 | |
| GSE54994 | CD226 | 10666 | 2 | 18 | 33 | |
| GSE60625 | CD226 | 10666 | 0 | 4 | 7 | |
| GSE74703 | CD226 | 10666 | 0 | 8 | 28 | |
| GSE74704 | CD226 | 10666 | 0 | 8 | 12 | |
| TCGA | CD226 | 10666 | 6 | 47 | 43 |
Total number of gains: 23; Total number of losses: 160; Total Number of normals: 305.
Somatic mutations of CD226:
Generating mutation plots.
Highly correlated genes for CD226:
Showing top 20/414 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD226 | GIMAP5 | 0.845539 | 3 | 0 | 3 |
| CD226 | C1orf162 | 0.808309 | 4 | 0 | 4 |
| CD226 | C16orf54 | 0.797642 | 4 | 0 | 4 |
| CD226 | SUSD3 | 0.754817 | 4 | 0 | 4 |
| CD226 | BBS12 | 0.753721 | 3 | 0 | 3 |
| CD226 | RCSD1 | 0.74925 | 4 | 0 | 4 |
| CD226 | NKG7 | 0.74628 | 8 | 0 | 8 |
| CD226 | ZSWIM1 | 0.742698 | 3 | 0 | 3 |
| CD226 | TLR1 | 0.737736 | 3 | 0 | 3 |
| CD226 | TTN | 0.736335 | 3 | 0 | 3 |
| CD226 | RGS18 | 0.734213 | 4 | 0 | 4 |
| CD226 | RAB8B | 0.727314 | 3 | 0 | 3 |
| CD226 | PARP15 | 0.721869 | 4 | 0 | 4 |
| CD226 | MS4A6A | 0.719468 | 5 | 0 | 5 |
| CD226 | IRF8 | 0.717969 | 6 | 0 | 5 |
| CD226 | GPR171 | 0.717531 | 8 | 0 | 7 |
| CD226 | GLCCI1 | 0.715647 | 4 | 0 | 4 |
| CD226 | SPI1 | 0.713371 | 4 | 0 | 4 |
| CD226 | PI15 | 0.703962 | 3 | 0 | 3 |
| CD226 | SCML4 | 0.701789 | 4 | 0 | 3 |
For details and further investigation, click here
