| Full name: solute carrier family 5 member 4 | Alias Symbol: SAAT1|SGLT3|DJ90G24.4 | ||
| Type: protein-coding gene | Cytoband: 22q12.3 | ||
| Entrez ID: 6527 | HGNC ID: HGNC:11039 | Ensembl Gene: ENSG00000100191 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SLC5A4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC5A4 | 6527 | 215960_at | 0.0176 | 0.9599 | |
| GSE20347 | SLC5A4 | 6527 | 215960_at | 0.0446 | 0.5984 | |
| GSE23400 | SLC5A4 | 6527 | 215960_at | -0.0845 | 0.0377 | |
| GSE26886 | SLC5A4 | 6527 | 215960_at | 0.0219 | 0.8346 | |
| GSE29001 | SLC5A4 | 6527 | 215960_at | -0.1074 | 0.5543 | |
| GSE38129 | SLC5A4 | 6527 | 215960_at | -0.0342 | 0.6829 | |
| GSE45670 | SLC5A4 | 6527 | 215960_at | 0.0136 | 0.9112 | |
| GSE53622 | SLC5A4 | 6527 | 86730 | -0.0069 | 0.9369 | |
| GSE53624 | SLC5A4 | 6527 | 86730 | 0.1169 | 0.1621 | |
| GSE63941 | SLC5A4 | 6527 | 215960_at | 0.0682 | 0.7038 | |
| GSE77861 | SLC5A4 | 6527 | 215960_at | -0.0679 | 0.3457 | |
| GSE97050 | SLC5A4 | 6527 | A_23_P57492 | 0.2160 | 0.2655 | |
| SRP133303 | SLC5A4 | 6527 | RNAseq | 0.8013 | 0.1567 | |
| SRP219564 | SLC5A4 | 6527 | RNAseq | 0.1940 | 0.7638 | |
| TCGA | SLC5A4 | 6527 | RNAseq | -0.0305 | 0.9687 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC5A4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC5A4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC5A4 | 6527 | 4 | 5 | 21 | |
| GSE20123 | SLC5A4 | 6527 | 4 | 4 | 22 | |
| GSE43470 | SLC5A4 | 6527 | 4 | 5 | 34 | |
| GSE46452 | SLC5A4 | 6527 | 31 | 1 | 27 | |
| GSE47630 | SLC5A4 | 6527 | 8 | 5 | 27 | |
| GSE54993 | SLC5A4 | 6527 | 3 | 6 | 61 | |
| GSE54994 | SLC5A4 | 6527 | 9 | 9 | 35 | |
| GSE60625 | SLC5A4 | 6527 | 5 | 0 | 6 | |
| GSE74703 | SLC5A4 | 6527 | 4 | 5 | 27 | |
| GSE74704 | SLC5A4 | 6527 | 1 | 1 | 18 | |
| TCGA | SLC5A4 | 6527 | 27 | 15 | 54 |
Total number of gains: 100; Total number of losses: 56; Total Number of normals: 332.
Somatic mutations of SLC5A4:
Generating mutation plots.
Highly correlated genes for SLC5A4:
Showing top 20/922 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC5A4 | LRRC31 | 0.799643 | 3 | 0 | 3 |
| SLC5A4 | NTNG1 | 0.777853 | 4 | 0 | 4 |
| SLC5A4 | NOX1 | 0.777826 | 4 | 0 | 4 |
| SLC5A4 | PRAMEF12 | 0.775002 | 5 | 0 | 5 |
| SLC5A4 | GCM2 | 0.770048 | 3 | 0 | 3 |
| SLC5A4 | PTPRN2 | 0.766271 | 4 | 0 | 4 |
| SLC5A4 | RNF17 | 0.751075 | 5 | 0 | 5 |
| SLC5A4 | ABCC2 | 0.747353 | 4 | 0 | 4 |
| SLC5A4 | NCR1 | 0.745537 | 5 | 0 | 5 |
| SLC5A4 | GLYATL1 | 0.741933 | 3 | 0 | 3 |
| SLC5A4 | RALYL | 0.74063 | 5 | 0 | 5 |
| SLC5A4 | KIR3DL3 | 0.738164 | 7 | 0 | 6 |
| SLC5A4 | SLCO1A2 | 0.736911 | 4 | 0 | 4 |
| SLC5A4 | PRR34 | 0.73499 | 4 | 0 | 4 |
| SLC5A4 | CBLN1 | 0.731295 | 3 | 0 | 3 |
| SLC5A4 | CIITA | 0.731206 | 4 | 0 | 4 |
| SLC5A4 | PLIN1 | 0.730885 | 3 | 0 | 3 |
| SLC5A4 | FSCN3 | 0.73048 | 6 | 0 | 5 |
| SLC5A4 | MYBPH | 0.729084 | 5 | 0 | 4 |
| SLC5A4 | KIF17 | 0.725287 | 4 | 0 | 3 |
For details and further investigation, click here
