| Full name: 5-hydroxytryptamine receptor 1F | Alias Symbol: HTR1EL|5-HT1F | ||
| Type: protein-coding gene | Cytoband: 3p12 | ||
| Entrez ID: 3355 | HGNC ID: HGNC:5292 | Ensembl Gene: ENSG00000179097 | OMIM ID: 182134 |
| Drug and gene relationship at DGIdb | |||
HTR1F involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04024 | cAMP signaling pathway | |
| hsa04726 | Serotonergic synapse | |
| hsa04742 | Taste transduction |
Expression of HTR1F:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HTR1F | 3355 | 221458_at | -0.0732 | 0.7894 | |
| GSE20347 | HTR1F | 3355 | 221458_at | 0.0695 | 0.4078 | |
| GSE23400 | HTR1F | 3355 | 221458_at | -0.0181 | 0.6480 | |
| GSE26886 | HTR1F | 3355 | 221458_at | 0.0272 | 0.8295 | |
| GSE29001 | HTR1F | 3355 | 221458_at | 0.0723 | 0.7418 | |
| GSE38129 | HTR1F | 3355 | 221458_at | -0.0000 | 0.9999 | |
| GSE45670 | HTR1F | 3355 | 221458_at | 0.1086 | 0.2175 | |
| GSE53622 | HTR1F | 3355 | 69274 | -0.7224 | 0.0000 | |
| GSE53624 | HTR1F | 3355 | 69274 | -0.7826 | 0.0000 | |
| GSE63941 | HTR1F | 3355 | 221458_at | -0.1819 | 0.2370 | |
| GSE77861 | HTR1F | 3355 | 221458_at | -0.0082 | 0.9365 | |
| GSE97050 | HTR1F | 3355 | A_33_P3406836 | 0.2534 | 0.3275 | |
| SRP133303 | HTR1F | 3355 | RNAseq | -0.6401 | 0.0590 | |
| TCGA | HTR1F | 3355 | RNAseq | 0.6890 | 0.1619 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HTR1F expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HTR1F:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HTR1F | 3355 | 3 | 15 | 12 | |
| GSE20123 | HTR1F | 3355 | 3 | 16 | 11 | |
| GSE43470 | HTR1F | 3355 | 4 | 19 | 20 | |
| GSE46452 | HTR1F | 3355 | 3 | 16 | 40 | |
| GSE47630 | HTR1F | 3355 | 4 | 18 | 18 | |
| GSE54993 | HTR1F | 3355 | 4 | 3 | 63 | |
| GSE54994 | HTR1F | 3355 | 3 | 27 | 23 | |
| GSE60625 | HTR1F | 3355 | 0 | 6 | 5 | |
| GSE74703 | HTR1F | 3355 | 4 | 17 | 15 | |
| GSE74704 | HTR1F | 3355 | 2 | 11 | 7 | |
| TCGA | HTR1F | 3355 | 3 | 70 | 23 |
Total number of gains: 33; Total number of losses: 218; Total Number of normals: 237.
Somatic mutations of HTR1F:
Generating mutation plots.
Highly correlated genes for HTR1F:
Showing top 20/262 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HTR1F | CRYBA1 | 0.783579 | 3 | 0 | 3 |
| HTR1F | IFNA17 | 0.741254 | 3 | 0 | 3 |
| HTR1F | SLC34A2 | 0.687129 | 3 | 0 | 3 |
| HTR1F | GAD2 | 0.682597 | 3 | 0 | 3 |
| HTR1F | TTLL10 | 0.679403 | 3 | 0 | 3 |
| HTR1F | WRNIP1 | 0.673621 | 3 | 0 | 3 |
| HTR1F | OR1A1 | 0.666884 | 4 | 0 | 4 |
| HTR1F | CLCA1 | 0.664136 | 4 | 0 | 3 |
| HTR1F | KCNV2 | 0.663459 | 4 | 0 | 4 |
| HTR1F | GP2 | 0.661057 | 4 | 0 | 4 |
| HTR1F | SERPINA4 | 0.655988 | 3 | 0 | 3 |
| HTR1F | KRT38 | 0.651293 | 4 | 0 | 4 |
| HTR1F | IKBKG | 0.649646 | 3 | 0 | 3 |
| HTR1F | PPEF2 | 0.647445 | 3 | 0 | 3 |
| HTR1F | TREML2 | 0.646979 | 3 | 0 | 3 |
| HTR1F | TEX15 | 0.64592 | 3 | 0 | 3 |
| HTR1F | HAVCR1 | 0.645637 | 4 | 0 | 3 |
| HTR1F | NR5A1 | 0.644121 | 3 | 0 | 3 |
| HTR1F | TAS2R16 | 0.641076 | 4 | 0 | 4 |
| HTR1F | KRT37 | 0.639323 | 3 | 0 | 3 |
For details and further investigation, click here
