EML2

 

Full name: EMAP like 2 Alias Symbol: EMAP2|ELP70|EMAP-2
Type: protein-coding gene Cytoband: 19q13.32
Entrez ID: 24139 HGNC ID: HGNC:18035 Ensembl Gene: ENSG00000125746 OMIM ID: 617494
Drug and gene relationship at DGIdb

 

Expression of EML2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 EML2 24139 204398_s_at -0.2727 0.5922
GSE20347 EML2 24139 204398_s_at -0.6033 0.0000
GSE23400 EML2 24139 204398_s_at -0.3758 0.0000
GSE26886 EML2 24139 204398_s_at -0.9395 0.0008
GSE29001 EML2 24139 204398_s_at -0.5646 0.1759
GSE38129 EML2 24139 204398_s_at -0.3221 0.0076
GSE45670 EML2 24139 204398_s_at 0.0062 0.9760
GSE53622 EML2 24139 114613 0.0418 0.5613
GSE53624 EML2 24139 100007 -0.9935 0.0000
GSE63941 EML2 24139 204398_s_at 1.5979 0.0004
GSE77861 EML2 24139 204398_s_at -0.1320 0.6667
GSE97050 EML2 24139 A_23_P101297 -0.0036 0.9939
SRP007169 EML2 24139 RNAseq -1.0596 0.0045
SRP008496 EML2 24139 RNAseq -1.7154 0.0000
SRP064894 EML2 24139 RNAseq -0.5289 0.0269
SRP133303 EML2 24139 RNAseq -0.6320 0.0004
SRP159526 EML2 24139 RNAseq -0.8141 0.0136
SRP193095 EML2 24139 RNAseq -0.5503 0.0000
SRP219564 EML2 24139 RNAseq -0.7976 0.1092
TCGA EML2 24139 RNAseq 0.0169 0.8147

Upregulated datasets: 1; Downregulated datasets: 2.  


 

Survival by EML2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of EML2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 EML2 24139 4 5 21
GSE20123 EML2 24139 4 4 22
GSE43470 EML2 24139 3 11 29
GSE46452 EML2 24139 45 1 13
GSE47630 EML2 24139 8 7 25
GSE54993 EML2 24139 17 4 49
GSE54994 EML2 24139 5 13 35
GSE60625 EML2 24139 9 0 2
GSE74703 EML2 24139 3 7 26
GSE74704 EML2 24139 4 2 14
TCGA EML2 24139 15 16 65

Total number of gains: 117; Total number of losses: 70; Total Number of normals: 301.  


 

Somatic mutations of EML2:

 

Generating mutation plots.

 

Highly correlated genes for EML2:

 

Showing top 20/474 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
EML2TFAP2C0.752008303
EML2RBM470.706645707
EML2POLL0.70046303
EML2DGAT20.689332404
EML2ESPNL0.687539403
EML2PGC0.687177404
EML2GALNT90.683528303
EML2PPIP5K10.677108404
EML2DEGS20.676978505
EML2CWH430.67534606
EML2PPM1N0.673782303
EML2EPHA10.673493908
EML2SFTPC0.672013504
EML2PAOX0.671477807
EML2EXPH50.671457707
EML2DNAH60.668211505
EML2DENND2D0.667313606
EML2ARHGAP270.665913404
EML2ATP13A40.665206303
EML2MAST40.663494807

For details and further investigation, click here