| Full name: lysine acetyltransferase 6A | Alias Symbol: MOZ|ZC2HC6A | ||
| Type: protein-coding gene | Cytoband: 8p11.21 | ||
| Entrez ID: 7994 | HGNC ID: HGNC:13013 | Ensembl Gene: ENSG00000083168 | OMIM ID: 601408 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of KAT6A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KAT6A | 7994 | 226547_at | 0.1625 | 0.7035 | |
| GSE20347 | KAT6A | 7994 | 202423_at | 0.2070 | 0.1595 | |
| GSE23400 | KAT6A | 7994 | 202423_at | 0.1250 | 0.1004 | |
| GSE26886 | KAT6A | 7994 | 226547_at | -0.0269 | 0.9302 | |
| GSE29001 | KAT6A | 7994 | 202423_at | 0.1146 | 0.6231 | |
| GSE38129 | KAT6A | 7994 | 202423_at | -0.0354 | 0.7788 | |
| GSE45670 | KAT6A | 7994 | 226547_at | -0.1336 | 0.3125 | |
| GSE63941 | KAT6A | 7994 | 202423_at | 0.0261 | 0.9524 | |
| GSE77861 | KAT6A | 7994 | 202423_at | 0.2197 | 0.3992 | |
| GSE97050 | KAT6A | 7994 | A_33_P3287735 | 0.0360 | 0.8706 | |
| SRP007169 | KAT6A | 7994 | RNAseq | 0.5948 | 0.1208 | |
| SRP008496 | KAT6A | 7994 | RNAseq | 0.3300 | 0.1745 | |
| SRP064894 | KAT6A | 7994 | RNAseq | -0.0566 | 0.8477 | |
| SRP133303 | KAT6A | 7994 | RNAseq | 0.1034 | 0.5380 | |
| SRP159526 | KAT6A | 7994 | RNAseq | -0.1895 | 0.4296 | |
| SRP193095 | KAT6A | 7994 | RNAseq | 0.1195 | 0.3117 | |
| SRP219564 | KAT6A | 7994 | RNAseq | -0.0546 | 0.8805 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of KAT6A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KAT6A | 7994 | 10 | 5 | 15 | |
| GSE20123 | KAT6A | 7994 | 10 | 6 | 14 | |
| GSE43470 | KAT6A | 7994 | 9 | 6 | 28 | |
| GSE46452 | KAT6A | 7994 | 19 | 5 | 35 | |
| GSE47630 | KAT6A | 7994 | 22 | 1 | 17 | |
| GSE54993 | KAT6A | 7994 | 1 | 16 | 53 | |
| GSE54994 | KAT6A | 7994 | 19 | 7 | 27 | |
| GSE60625 | KAT6A | 7994 | 3 | 0 | 8 | |
| GSE74703 | KAT6A | 7994 | 8 | 5 | 23 | |
| GSE74704 | KAT6A | 7994 | 9 | 2 | 9 | |
| TCGA | KAT6A | 7994 | 39 | 21 | 36 |
Total number of gains: 149; Total number of losses: 74; Total Number of normals: 265.
Somatic mutations of KAT6A:
Generating mutation plots.
Highly correlated genes for KAT6A:
Showing top 20/29 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KAT6A | ZMYM4 | 0.67496 | 3 | 0 | 3 |
| KAT6A | IKBKB | 0.641205 | 8 | 0 | 7 |
| KAT6A | RCC2 | 0.609114 | 3 | 0 | 3 |
| KAT6A | PPIP5K1 | 0.605518 | 3 | 0 | 3 |
| KAT6A | MID1 | 0.604656 | 4 | 0 | 3 |
| KAT6A | PSD3 | 0.604169 | 4 | 0 | 3 |
| KAT6A | RPRD1B | 0.604122 | 3 | 0 | 3 |
| KAT6A | PPM1L | 0.59952 | 3 | 0 | 3 |
| KAT6A | DNAJC16 | 0.599092 | 4 | 0 | 3 |
| KAT6A | ZFAND4 | 0.597484 | 3 | 0 | 3 |
| KAT6A | LHX6 | 0.576876 | 3 | 0 | 3 |
| KAT6A | LEMD3 | 0.571378 | 4 | 0 | 4 |
| KAT6A | BAG4 | 0.564279 | 7 | 0 | 4 |
| KAT6A | PHKA2 | 0.559388 | 5 | 0 | 3 |
| KAT6A | POLB | 0.551031 | 5 | 0 | 4 |
| KAT6A | BRF2 | 0.550349 | 6 | 0 | 4 |
| KAT6A | RBBP7 | 0.540663 | 4 | 0 | 3 |
| KAT6A | PAN2 | 0.540463 | 7 | 0 | 4 |
| KAT6A | ERLIN2 | 0.537624 | 6 | 0 | 3 |
| KAT6A | POLA1 | 0.536627 | 5 | 0 | 3 |
For details and further investigation, click here
