| Full name: cell adhesion molecule 4 | Alias Symbol: TSLL2|Necl-4|SynCAM4 | ||
| Type: protein-coding gene | Cytoband: 19q13.31 | ||
| Entrez ID: 199731 | HGNC ID: HGNC:30825 | Ensembl Gene: ENSG00000105767 | OMIM ID: 609744 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CADM4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CADM4 | 199731 | 222293_at | 0.0633 | 0.9204 | |
| GSE20347 | CADM4 | 199731 | 215258_at | -0.0995 | 0.2162 | |
| GSE23400 | CADM4 | 199731 | 215258_at | -0.1143 | 0.0005 | |
| GSE26886 | CADM4 | 199731 | 215258_at | 0.1837 | 0.1414 | |
| GSE29001 | CADM4 | 199731 | 222293_at | -0.3186 | 0.5358 | |
| GSE38129 | CADM4 | 199731 | 215258_at | -0.1527 | 0.0107 | |
| GSE45670 | CADM4 | 199731 | 214267_s_at | -0.0206 | 0.8480 | |
| GSE53622 | CADM4 | 199731 | 99931 | 0.2130 | 0.0230 | |
| GSE53624 | CADM4 | 199731 | 99931 | 0.1094 | 0.0823 | |
| GSE63941 | CADM4 | 199731 | 229335_at | 0.7421 | 0.0265 | |
| GSE77861 | CADM4 | 199731 | 229335_at | 0.1890 | 0.3505 | |
| GSE97050 | CADM4 | 199731 | A_23_P5064 | -0.3017 | 0.2151 | |
| SRP007169 | CADM4 | 199731 | RNAseq | -0.3915 | 0.4914 | |
| SRP008496 | CADM4 | 199731 | RNAseq | -0.6106 | 0.1407 | |
| SRP064894 | CADM4 | 199731 | RNAseq | -0.2560 | 0.2612 | |
| SRP133303 | CADM4 | 199731 | RNAseq | -0.2352 | 0.2856 | |
| SRP159526 | CADM4 | 199731 | RNAseq | 0.8205 | 0.0836 | |
| SRP193095 | CADM4 | 199731 | RNAseq | -0.1656 | 0.5408 | |
| SRP219564 | CADM4 | 199731 | RNAseq | -0.7433 | 0.1496 | |
| TCGA | CADM4 | 199731 | RNAseq | -0.1155 | 0.3512 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CADM4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CADM4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CADM4 | 199731 | 6 | 5 | 19 | |
| GSE20123 | CADM4 | 199731 | 5 | 4 | 21 | |
| GSE43470 | CADM4 | 199731 | 4 | 11 | 28 | |
| GSE46452 | CADM4 | 199731 | 45 | 1 | 13 | |
| GSE47630 | CADM4 | 199731 | 8 | 6 | 26 | |
| GSE54993 | CADM4 | 199731 | 17 | 4 | 49 | |
| GSE54994 | CADM4 | 199731 | 6 | 12 | 35 | |
| GSE60625 | CADM4 | 199731 | 9 | 0 | 2 | |
| GSE74703 | CADM4 | 199731 | 4 | 7 | 25 | |
| GSE74704 | CADM4 | 199731 | 4 | 2 | 14 | |
| TCGA | CADM4 | 199731 | 14 | 16 | 66 |
Total number of gains: 122; Total number of losses: 68; Total Number of normals: 298.
Somatic mutations of CADM4:
Generating mutation plots.
Highly correlated genes for CADM4:
Showing top 20/220 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CADM4 | C19orf25 | 0.790192 | 3 | 0 | 3 |
| CADM4 | ARL8A | 0.763291 | 3 | 0 | 3 |
| CADM4 | GRIPAP1 | 0.746271 | 3 | 0 | 3 |
| CADM4 | TMUB1 | 0.722364 | 4 | 0 | 4 |
| CADM4 | IGSF9B | 0.702789 | 3 | 0 | 3 |
| CADM4 | VWDE | 0.702282 | 3 | 0 | 3 |
| CADM4 | LRRN4 | 0.700867 | 3 | 0 | 3 |
| CADM4 | WNT9A | 0.698022 | 3 | 0 | 3 |
| CADM4 | NAT9 | 0.694719 | 3 | 0 | 3 |
| CADM4 | ADAP1 | 0.690626 | 5 | 0 | 5 |
| CADM4 | JSRP1 | 0.690128 | 3 | 0 | 3 |
| CADM4 | CFC1 | 0.686087 | 3 | 0 | 3 |
| CADM4 | FAM181A | 0.682999 | 4 | 0 | 3 |
| CADM4 | RASL10B | 0.679614 | 4 | 0 | 3 |
| CADM4 | BATF2 | 0.679245 | 3 | 0 | 3 |
| CADM4 | TBX21 | 0.675904 | 3 | 0 | 3 |
| CADM4 | LRSAM1 | 0.674441 | 4 | 0 | 4 |
| CADM4 | FBLN7 | 0.672175 | 4 | 0 | 3 |
| CADM4 | DOK7 | 0.670155 | 4 | 0 | 3 |
| CADM4 | ZMYND8 | 0.665679 | 3 | 0 | 3 |
For details and further investigation, click here
