| Full name: PR/SET domain 5 | Alias Symbol: PFM2 | ||
| Type: protein-coding gene | Cytoband: 4q27 | ||
| Entrez ID: 11107 | HGNC ID: HGNC:9349 | Ensembl Gene: ENSG00000138738 | OMIM ID: 614161 |
| Drug and gene relationship at DGIdb | |||
Expression of PRDM5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRDM5 | 11107 | 220792_at | -0.0062 | 0.9883 | |
| GSE20347 | PRDM5 | 11107 | 220792_at | 0.0147 | 0.8738 | |
| GSE23400 | PRDM5 | 11107 | 220792_at | -0.1189 | 0.0002 | |
| GSE26886 | PRDM5 | 11107 | 220792_at | 0.0024 | 0.9823 | |
| GSE29001 | PRDM5 | 11107 | 220792_at | 0.0056 | 0.9778 | |
| GSE38129 | PRDM5 | 11107 | 220792_at | -0.0497 | 0.4810 | |
| GSE45670 | PRDM5 | 11107 | 235764_at | -1.2868 | 0.0000 | |
| GSE53622 | PRDM5 | 11107 | 79068 | -0.4066 | 0.0020 | |
| GSE53624 | PRDM5 | 11107 | 79068 | -0.2015 | 0.0405 | |
| GSE63941 | PRDM5 | 11107 | 220792_at | -0.3013 | 0.3510 | |
| GSE77861 | PRDM5 | 11107 | 220792_at | 0.0903 | 0.3280 | |
| GSE97050 | PRDM5 | 11107 | A_33_P3242548 | -0.2846 | 0.3062 | |
| SRP007169 | PRDM5 | 11107 | RNAseq | -0.4830 | 0.3721 | |
| SRP008496 | PRDM5 | 11107 | RNAseq | -0.1234 | 0.7343 | |
| SRP064894 | PRDM5 | 11107 | RNAseq | -0.2774 | 0.1856 | |
| SRP133303 | PRDM5 | 11107 | RNAseq | -0.5146 | 0.0850 | |
| SRP159526 | PRDM5 | 11107 | RNAseq | -0.2120 | 0.5115 | |
| SRP193095 | PRDM5 | 11107 | RNAseq | -0.1583 | 0.4545 | |
| SRP219564 | PRDM5 | 11107 | RNAseq | -0.3136 | 0.6110 | |
| TCGA | PRDM5 | 11107 | RNAseq | -0.4385 | 0.0349 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PRDM5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRDM5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRDM5 | 11107 | 0 | 13 | 17 | |
| GSE20123 | PRDM5 | 11107 | 0 | 13 | 17 | |
| GSE43470 | PRDM5 | 11107 | 0 | 13 | 30 | |
| GSE46452 | PRDM5 | 11107 | 1 | 36 | 22 | |
| GSE47630 | PRDM5 | 11107 | 0 | 22 | 18 | |
| GSE54993 | PRDM5 | 11107 | 9 | 0 | 61 | |
| GSE54994 | PRDM5 | 11107 | 1 | 10 | 42 | |
| GSE60625 | PRDM5 | 11107 | 0 | 1 | 10 | |
| GSE74703 | PRDM5 | 11107 | 0 | 11 | 25 | |
| GSE74704 | PRDM5 | 11107 | 0 | 7 | 13 | |
| TCGA | PRDM5 | 11107 | 8 | 34 | 54 |
Total number of gains: 19; Total number of losses: 160; Total Number of normals: 309.
Somatic mutations of PRDM5:
Generating mutation plots.
Highly correlated genes for PRDM5:
Showing top 20/348 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRDM5 | OLFML1 | 0.808398 | 3 | 0 | 3 |
| PRDM5 | CLASP1 | 0.7835 | 3 | 0 | 3 |
| PRDM5 | RAB23 | 0.740907 | 3 | 0 | 3 |
| PRDM5 | EHD2 | 0.739114 | 3 | 0 | 3 |
| PRDM5 | CDKN1C | 0.734817 | 3 | 0 | 3 |
| PRDM5 | STARD9 | 0.728004 | 3 | 0 | 3 |
| PRDM5 | MYOCD | 0.7248 | 3 | 0 | 3 |
| PRDM5 | TGFBR1 | 0.71868 | 3 | 0 | 3 |
| PRDM5 | IGDCC4 | 0.718487 | 3 | 0 | 3 |
| PRDM5 | PTBP2 | 0.716914 | 3 | 0 | 3 |
| PRDM5 | USP40 | 0.713506 | 3 | 0 | 3 |
| PRDM5 | RGL1 | 0.706406 | 3 | 0 | 3 |
| PRDM5 | OCM2 | 0.7034 | 3 | 0 | 3 |
| PRDM5 | TMOD2 | 0.699157 | 4 | 0 | 4 |
| PRDM5 | PCDH18 | 0.696745 | 4 | 0 | 3 |
| PRDM5 | ZMIZ2 | 0.694023 | 3 | 0 | 3 |
| PRDM5 | SGTB | 0.691553 | 3 | 0 | 3 |
| PRDM5 | LMNA | 0.682963 | 4 | 0 | 3 |
| PRDM5 | STARD13 | 0.680494 | 4 | 0 | 4 |
| PRDM5 | FAM13C | 0.679729 | 4 | 0 | 3 |
For details and further investigation, click here
