| Full name: RAB23, member RAS oncogene family | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p12.1-p11.2 | ||
| Entrez ID: 51715 | HGNC ID: HGNC:14263 | Ensembl Gene: ENSG00000112210 | OMIM ID: 606144 |
| Drug and gene relationship at DGIdb | |||
Expression of RAB23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB23 | 51715 | 223463_at | -0.2152 | 0.8537 | |
| GSE20347 | RAB23 | 51715 | 220955_x_at | 0.2022 | 0.0405 | |
| GSE23400 | RAB23 | 51715 | 220955_x_at | 0.1039 | 0.1854 | |
| GSE26886 | RAB23 | 51715 | 223463_at | 1.1118 | 0.0021 | |
| GSE29001 | RAB23 | 51715 | 220955_x_at | -0.1056 | 0.6307 | |
| GSE38129 | RAB23 | 51715 | 220955_x_at | 0.1696 | 0.2629 | |
| GSE45670 | RAB23 | 51715 | 223463_at | -0.2825 | 0.4507 | |
| GSE63941 | RAB23 | 51715 | 223463_at | -2.5917 | 0.0003 | |
| GSE77861 | RAB23 | 51715 | 223463_at | 1.1713 | 0.0247 | |
| GSE97050 | RAB23 | 51715 | A_23_P70794 | -0.2347 | 0.3903 | |
| SRP007169 | RAB23 | 51715 | RNAseq | 1.7767 | 0.0000 | |
| SRP008496 | RAB23 | 51715 | RNAseq | 2.3342 | 0.0000 | |
| SRP064894 | RAB23 | 51715 | RNAseq | 0.7338 | 0.0183 | |
| SRP133303 | RAB23 | 51715 | RNAseq | 0.7694 | 0.0340 | |
| SRP159526 | RAB23 | 51715 | RNAseq | 0.4277 | 0.2942 | |
| SRP193095 | RAB23 | 51715 | RNAseq | 0.9919 | 0.0000 | |
| SRP219564 | RAB23 | 51715 | RNAseq | -0.2947 | 0.7041 | |
| TCGA | RAB23 | 51715 | RNAseq | -0.0606 | 0.4651 |
Upregulated datasets: 4; Downregulated datasets: 1.
Survival by RAB23 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RAB23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB23 | 51715 | 7 | 2 | 21 | |
| GSE20123 | RAB23 | 51715 | 7 | 2 | 21 | |
| GSE43470 | RAB23 | 51715 | 4 | 0 | 39 | |
| GSE46452 | RAB23 | 51715 | 2 | 10 | 47 | |
| GSE47630 | RAB23 | 51715 | 7 | 5 | 28 | |
| GSE54993 | RAB23 | 51715 | 3 | 2 | 65 | |
| GSE54994 | RAB23 | 51715 | 9 | 4 | 40 | |
| GSE60625 | RAB23 | 51715 | 0 | 1 | 10 | |
| GSE74703 | RAB23 | 51715 | 4 | 0 | 32 | |
| GSE74704 | RAB23 | 51715 | 3 | 1 | 16 | |
| TCGA | RAB23 | 51715 | 22 | 10 | 64 |
Total number of gains: 68; Total number of losses: 37; Total Number of normals: 383.
Somatic mutations of RAB23:
Generating mutation plots.
Highly correlated genes for RAB23:
Showing top 20/954 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB23 | CLMP | 0.831111 | 4 | 0 | 4 |
| RAB23 | ZNF25 | 0.797262 | 3 | 0 | 3 |
| RAB23 | TTC7B | 0.793187 | 5 | 0 | 5 |
| RAB23 | IGIP | 0.78937 | 3 | 0 | 3 |
| RAB23 | STK32B | 0.786228 | 3 | 0 | 3 |
| RAB23 | SPOPL | 0.783756 | 4 | 0 | 4 |
| RAB23 | ANO6 | 0.781372 | 6 | 0 | 6 |
| RAB23 | ASB7 | 0.780542 | 3 | 0 | 3 |
| RAB23 | ATP10A | 0.761347 | 3 | 0 | 3 |
| RAB23 | C5orf24 | 0.754942 | 3 | 0 | 3 |
| RAB23 | DOK1 | 0.752626 | 3 | 0 | 3 |
| RAB23 | PRPH2 | 0.751508 | 3 | 0 | 3 |
| RAB23 | TMEM263 | 0.751275 | 5 | 0 | 5 |
| RAB23 | RILPL1 | 0.750377 | 4 | 0 | 4 |
| RAB23 | STARD3NL | 0.748113 | 4 | 0 | 4 |
| RAB23 | ERRFI1 | 0.747712 | 4 | 0 | 4 |
| RAB23 | ZNF382 | 0.746845 | 4 | 0 | 4 |
| RAB23 | PRTFDC1 | 0.741068 | 5 | 0 | 5 |
| RAB23 | CYP2U1 | 0.74101 | 3 | 0 | 3 |
| RAB23 | PRDM5 | 0.740907 | 3 | 0 | 3 |
For details and further investigation, click here
