| Full name: immunoglobulin superfamily DCC subclass member 4 | Alias Symbol: NOPE|LOC57722 | ||
| Type: protein-coding gene | Cytoband: 15q22.31 | ||
| Entrez ID: 57722 | HGNC ID: HGNC:13770 | Ensembl Gene: ENSG00000103742 | OMIM ID: 616810 |
| Drug and gene relationship at DGIdb | |||
Expression of IGDCC4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IGDCC4 | 57722 | 227870_at | -0.4864 | 0.6566 | |
| GSE26886 | IGDCC4 | 57722 | 227870_at | 0.4587 | 0.2375 | |
| GSE45670 | IGDCC4 | 57722 | 227870_at | -1.4060 | 0.0148 | |
| GSE53622 | IGDCC4 | 57722 | 99364 | 0.0382 | 0.8513 | |
| GSE53624 | IGDCC4 | 57722 | 99364 | 0.1826 | 0.3888 | |
| GSE63941 | IGDCC4 | 57722 | 227870_at | -0.9838 | 0.0236 | |
| GSE77861 | IGDCC4 | 57722 | 227870_at | 0.2064 | 0.2052 | |
| GSE97050 | IGDCC4 | 57722 | A_23_P14673 | -0.1653 | 0.6699 | |
| SRP007169 | IGDCC4 | 57722 | RNAseq | 3.2938 | 0.0015 | |
| SRP064894 | IGDCC4 | 57722 | RNAseq | 0.5369 | 0.1676 | |
| SRP133303 | IGDCC4 | 57722 | RNAseq | -0.1011 | 0.7252 | |
| SRP159526 | IGDCC4 | 57722 | RNAseq | 0.0052 | 0.9895 | |
| SRP193095 | IGDCC4 | 57722 | RNAseq | 1.7293 | 0.0000 | |
| SRP219564 | IGDCC4 | 57722 | RNAseq | 0.4212 | 0.3816 | |
| TCGA | IGDCC4 | 57722 | RNAseq | -0.4353 | 0.0165 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by IGDCC4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IGDCC4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IGDCC4 | 57722 | 7 | 3 | 20 | |
| GSE20123 | IGDCC4 | 57722 | 7 | 3 | 20 | |
| GSE43470 | IGDCC4 | 57722 | 4 | 6 | 33 | |
| GSE46452 | IGDCC4 | 57722 | 3 | 7 | 49 | |
| GSE47630 | IGDCC4 | 57722 | 8 | 10 | 22 | |
| GSE54993 | IGDCC4 | 57722 | 5 | 6 | 59 | |
| GSE54994 | IGDCC4 | 57722 | 6 | 7 | 40 | |
| GSE60625 | IGDCC4 | 57722 | 4 | 0 | 7 | |
| GSE74703 | IGDCC4 | 57722 | 4 | 3 | 29 | |
| GSE74704 | IGDCC4 | 57722 | 3 | 3 | 14 | |
| TCGA | IGDCC4 | 57722 | 10 | 16 | 70 |
Total number of gains: 61; Total number of losses: 64; Total Number of normals: 363.
Somatic mutations of IGDCC4:
Generating mutation plots.
Highly correlated genes for IGDCC4:
Showing top 20/760 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IGDCC4 | OLFML1 | 0.790043 | 9 | 0 | 9 |
| IGDCC4 | FBN1 | 0.758019 | 7 | 0 | 7 |
| IGDCC4 | MRC1 | 0.75325 | 7 | 0 | 7 |
| IGDCC4 | TYW3 | 0.751256 | 3 | 0 | 3 |
| IGDCC4 | CNRIP1 | 0.736928 | 9 | 0 | 9 |
| IGDCC4 | GLT8D2 | 0.736913 | 8 | 0 | 7 |
| IGDCC4 | PRPS1 | 0.726457 | 3 | 0 | 3 |
| IGDCC4 | VSTM4 | 0.721028 | 7 | 0 | 7 |
| IGDCC4 | IRAK3 | 0.719687 | 5 | 0 | 5 |
| IGDCC4 | PRDM5 | 0.718487 | 3 | 0 | 3 |
| IGDCC4 | PMP22 | 0.718168 | 8 | 0 | 8 |
| IGDCC4 | ATG12 | 0.715003 | 3 | 0 | 3 |
| IGDCC4 | CTSK | 0.713406 | 9 | 0 | 8 |
| IGDCC4 | JMY | 0.712438 | 3 | 0 | 3 |
| IGDCC4 | OLFML3 | 0.712309 | 9 | 0 | 9 |
| IGDCC4 | BHLHE22 | 0.704618 | 6 | 0 | 5 |
| IGDCC4 | C19orf38 | 0.701854 | 3 | 0 | 3 |
| IGDCC4 | DCN | 0.69884 | 9 | 0 | 9 |
| IGDCC4 | PTPRB | 0.697338 | 6 | 0 | 5 |
| IGDCC4 | FLI1 | 0.694999 | 6 | 0 | 5 |
For details and further investigation, click here
