| Full name: EH domain containing 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 30846 | HGNC ID: HGNC:3243 | Ensembl Gene: ENSG00000024422 | OMIM ID: 605890 |
| Drug and gene relationship at DGIdb | |||
Expression of EHD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EHD2 | 30846 | 221870_at | -0.0280 | 0.9774 | |
| GSE20347 | EHD2 | 30846 | 221870_at | 0.2371 | 0.1659 | |
| GSE23400 | EHD2 | 30846 | 221870_at | 0.0720 | 0.4079 | |
| GSE26886 | EHD2 | 30846 | 221870_at | 0.2405 | 0.3093 | |
| GSE29001 | EHD2 | 30846 | 221870_at | 0.3300 | 0.4628 | |
| GSE38129 | EHD2 | 30846 | 221870_at | -0.1582 | 0.5234 | |
| GSE45670 | EHD2 | 30846 | 221870_at | 0.2142 | 0.3873 | |
| GSE53622 | EHD2 | 30846 | 93655 | -0.0199 | 0.8873 | |
| GSE53624 | EHD2 | 30846 | 93655 | 0.5482 | 0.0000 | |
| GSE63941 | EHD2 | 30846 | 221870_at | -1.6410 | 0.0058 | |
| GSE77861 | EHD2 | 30846 | 221870_at | 0.5070 | 0.2043 | |
| GSE97050 | EHD2 | 30846 | A_24_P156113 | -0.1345 | 0.7561 | |
| SRP007169 | EHD2 | 30846 | RNAseq | 1.1736 | 0.0009 | |
| SRP008496 | EHD2 | 30846 | RNAseq | 1.2386 | 0.0000 | |
| SRP064894 | EHD2 | 30846 | RNAseq | 0.9716 | 0.0001 | |
| SRP133303 | EHD2 | 30846 | RNAseq | 0.5707 | 0.0773 | |
| SRP159526 | EHD2 | 30846 | RNAseq | -0.2050 | 0.5851 | |
| SRP193095 | EHD2 | 30846 | RNAseq | 1.1947 | 0.0000 | |
| SRP219564 | EHD2 | 30846 | RNAseq | -0.0103 | 0.9851 | |
| TCGA | EHD2 | 30846 | RNAseq | 0.0603 | 0.4280 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by EHD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EHD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EHD2 | 30846 | 4 | 4 | 22 | |
| GSE20123 | EHD2 | 30846 | 4 | 3 | 23 | |
| GSE43470 | EHD2 | 30846 | 3 | 10 | 30 | |
| GSE46452 | EHD2 | 30846 | 45 | 1 | 13 | |
| GSE47630 | EHD2 | 30846 | 8 | 7 | 25 | |
| GSE54993 | EHD2 | 30846 | 17 | 4 | 49 | |
| GSE54994 | EHD2 | 30846 | 4 | 14 | 35 | |
| GSE60625 | EHD2 | 30846 | 9 | 0 | 2 | |
| GSE74703 | EHD2 | 30846 | 3 | 7 | 26 | |
| GSE74704 | EHD2 | 30846 | 4 | 1 | 15 | |
| TCGA | EHD2 | 30846 | 15 | 18 | 63 |
Total number of gains: 116; Total number of losses: 69; Total Number of normals: 303.
Somatic mutations of EHD2:
Generating mutation plots.
Highly correlated genes for EHD2:
Showing top 20/777 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EHD2 | PCDH18 | 0.756445 | 3 | 0 | 3 |
| EHD2 | SYNC | 0.745137 | 4 | 0 | 4 |
| EHD2 | PRDM5 | 0.739114 | 3 | 0 | 3 |
| EHD2 | JDP2 | 0.728088 | 3 | 0 | 3 |
| EHD2 | PYROXD2 | 0.726789 | 3 | 0 | 3 |
| EHD2 | TRIM47 | 0.725129 | 4 | 0 | 4 |
| EHD2 | HSD11B1 | 0.705076 | 3 | 0 | 3 |
| EHD2 | RRAS | 0.701185 | 12 | 0 | 10 |
| EHD2 | KCTD10 | 0.694564 | 3 | 0 | 3 |
| EHD2 | HGF | 0.692586 | 3 | 0 | 3 |
| EHD2 | KRTAP1-3 | 0.678003 | 3 | 0 | 3 |
| EHD2 | EDNRB | 0.677762 | 4 | 0 | 3 |
| EHD2 | INPP5E | 0.677554 | 3 | 0 | 3 |
| EHD2 | NMT2 | 0.676922 | 3 | 0 | 3 |
| EHD2 | ASPA | 0.676276 | 3 | 0 | 3 |
| EHD2 | KATNAL1 | 0.675683 | 6 | 0 | 5 |
| EHD2 | KCNJ8 | 0.673843 | 7 | 0 | 6 |
| EHD2 | ARHGAP6 | 0.672342 | 4 | 0 | 3 |
| EHD2 | C20orf194 | 0.670883 | 4 | 0 | 4 |
| EHD2 | DOCK11 | 0.670801 | 4 | 0 | 3 |
For details and further investigation, click here
