| Full name: proteoglycan 3, pro eosinophil major basic protein 2 | Alias Symbol: MBPH|MBP2 | ||
| Type: protein-coding gene | Cytoband: 11q12.1 | ||
| Entrez ID: 10394 | HGNC ID: HGNC:9363 | Ensembl Gene: ENSG00000156575 | OMIM ID: 606814 |
| Drug and gene relationship at DGIdb | |||
Expression of PRG3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRG3 | 10394 | 220811_at | -0.1319 | 0.5327 | |
| GSE20347 | PRG3 | 10394 | 220811_at | -0.0897 | 0.1876 | |
| GSE23400 | PRG3 | 10394 | 220811_at | -0.1164 | 0.0002 | |
| GSE26886 | PRG3 | 10394 | 220811_at | -0.0033 | 0.9827 | |
| GSE29001 | PRG3 | 10394 | 220811_at | -0.1243 | 0.2213 | |
| GSE38129 | PRG3 | 10394 | 220811_at | -0.1403 | 0.0469 | |
| GSE45670 | PRG3 | 10394 | 220811_at | 0.0281 | 0.7859 | |
| GSE53622 | PRG3 | 10394 | 13209 | -0.2320 | 0.0004 | |
| GSE53624 | PRG3 | 10394 | 13209 | -0.1879 | 0.0251 | |
| GSE63941 | PRG3 | 10394 | 220811_at | -0.0076 | 0.9641 | |
| GSE77861 | PRG3 | 10394 | 220811_at | 0.0094 | 0.9538 | |
| GSE97050 | PRG3 | 10394 | A_23_P47466 | 0.0758 | 0.7515 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRG3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRG3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRG3 | 10394 | 2 | 3 | 25 | |
| GSE20123 | PRG3 | 10394 | 2 | 3 | 25 | |
| GSE43470 | PRG3 | 10394 | 1 | 5 | 37 | |
| GSE46452 | PRG3 | 10394 | 8 | 4 | 47 | |
| GSE47630 | PRG3 | 10394 | 3 | 9 | 28 | |
| GSE54993 | PRG3 | 10394 | 3 | 0 | 67 | |
| GSE54994 | PRG3 | 10394 | 5 | 6 | 42 | |
| GSE60625 | PRG3 | 10394 | 0 | 3 | 8 | |
| GSE74703 | PRG3 | 10394 | 1 | 3 | 32 | |
| GSE74704 | PRG3 | 10394 | 2 | 3 | 15 | |
| TCGA | PRG3 | 10394 | 14 | 10 | 72 |
Total number of gains: 41; Total number of losses: 49; Total Number of normals: 398.
Somatic mutations of PRG3:
Generating mutation plots.
Highly correlated genes for PRG3:
Showing top 20/778 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRG3 | GDF7 | 0.849559 | 3 | 0 | 3 |
| PRG3 | SLC22A12 | 0.828178 | 4 | 0 | 4 |
| PRG3 | TPRX1 | 0.826267 | 3 | 0 | 3 |
| PRG3 | TSSK3 | 0.811862 | 3 | 0 | 3 |
| PRG3 | IGLON5 | 0.810199 | 3 | 0 | 3 |
| PRG3 | BSND | 0.808379 | 3 | 0 | 3 |
| PRG3 | PRSS38 | 0.80649 | 3 | 0 | 3 |
| PRG3 | YY2 | 0.805476 | 3 | 0 | 3 |
| PRG3 | KRTAP6-1 | 0.80129 | 3 | 0 | 3 |
| PRG3 | PIP5KL1 | 0.800061 | 3 | 0 | 3 |
| PRG3 | BSX | 0.797788 | 3 | 0 | 3 |
| PRG3 | OTOG | 0.797353 | 3 | 0 | 3 |
| PRG3 | TTC7A | 0.789174 | 3 | 0 | 3 |
| PRG3 | OR5A1 | 0.786005 | 3 | 0 | 3 |
| PRG3 | SPN | 0.783368 | 3 | 0 | 3 |
| PRG3 | ZNF852 | 0.77933 | 3 | 0 | 3 |
| PRG3 | C1QL2 | 0.777286 | 3 | 0 | 3 |
| PRG3 | SCARA5 | 0.776 | 4 | 0 | 4 |
| PRG3 | OR4C3 | 0.77599 | 3 | 0 | 3 |
| PRG3 | CIB3 | 0.772518 | 3 | 0 | 3 |
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