| Full name: sialophorin | Alias Symbol: LSN|CD43|GPL115 | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 6693 | HGNC ID: HGNC:11249 | Ensembl Gene: ENSG00000197471 | OMIM ID: 182160 |
| Drug and gene relationship at DGIdb | |||
Expression of SPN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | SPN | 6693 | 14056 | -0.1462 | 0.0351 | |
| GSE53624 | SPN | 6693 | 14056 | -0.1849 | 0.0078 | |
| GSE97050 | SPN | 6693 | A_33_P3404706 | 0.0512 | 0.8634 | |
| SRP007169 | SPN | 6693 | RNAseq | -0.2550 | 0.6785 | |
| SRP008496 | SPN | 6693 | RNAseq | -0.1992 | 0.6584 | |
| SRP064894 | SPN | 6693 | RNAseq | -0.0439 | 0.8529 | |
| SRP133303 | SPN | 6693 | RNAseq | -0.2157 | 0.0158 | |
| SRP159526 | SPN | 6693 | RNAseq | -0.9158 | 0.0828 | |
| SRP193095 | SPN | 6693 | RNAseq | -0.2525 | 0.0196 | |
| SRP219564 | SPN | 6693 | RNAseq | -0.1784 | 0.7801 | |
| TCGA | SPN | 6693 | RNAseq | 0.0950 | 0.5912 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPN | 6693 | 5 | 5 | 20 | |
| GSE20123 | SPN | 6693 | 5 | 4 | 21 | |
| GSE43470 | SPN | 6693 | 3 | 3 | 37 | |
| GSE46452 | SPN | 6693 | 38 | 1 | 20 | |
| GSE47630 | SPN | 6693 | 11 | 7 | 22 | |
| GSE54993 | SPN | 6693 | 3 | 5 | 62 | |
| GSE54994 | SPN | 6693 | 5 | 9 | 39 | |
| GSE60625 | SPN | 6693 | 4 | 0 | 7 | |
| GSE74703 | SPN | 6693 | 3 | 2 | 31 | |
| GSE74704 | SPN | 6693 | 3 | 2 | 15 | |
| TCGA | SPN | 6693 | 20 | 11 | 65 |
Total number of gains: 100; Total number of losses: 49; Total Number of normals: 339.
Somatic mutations of SPN:
Generating mutation plots.
Highly correlated genes for SPN:
Showing top 20/99 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPN | FXYD2 | 0.808751 | 3 | 0 | 3 |
| SPN | PRSS38 | 0.798753 | 3 | 0 | 3 |
| SPN | TTC7A | 0.789557 | 3 | 0 | 3 |
| SPN | PRG3 | 0.783368 | 3 | 0 | 3 |
| SPN | YY2 | 0.781874 | 3 | 0 | 3 |
| SPN | PLA2G2D | 0.780447 | 4 | 0 | 4 |
| SPN | PDZRN3 | 0.766174 | 3 | 0 | 3 |
| SPN | PAX2 | 0.757413 | 3 | 0 | 3 |
| SPN | SLC22A12 | 0.751215 | 3 | 0 | 3 |
| SPN | KRT77 | 0.751183 | 3 | 0 | 3 |
| SPN | SHROOM4 | 0.751067 | 4 | 0 | 4 |
| SPN | MAP3K10 | 0.747229 | 3 | 0 | 3 |
| SPN | TERT | 0.746766 | 3 | 0 | 3 |
| SPN | BTK | 0.744992 | 3 | 0 | 3 |
| SPN | SIGIRR | 0.737721 | 3 | 0 | 3 |
| SPN | C1QL2 | 0.737601 | 3 | 0 | 3 |
| SPN | TSSK3 | 0.73666 | 3 | 0 | 3 |
| SPN | ZNF524 | 0.733637 | 3 | 0 | 3 |
| SPN | RBM43 | 0.733296 | 3 | 0 | 3 |
| SPN | PPA2 | 0.732552 | 4 | 0 | 3 |
For details and further investigation, click here
