| Full name: proline rich 15 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p14.3 | ||
| Entrez ID: 222171 | HGNC ID: HGNC:22310 | Ensembl Gene: ENSG00000176532 | OMIM ID: 618344 |
| Drug and gene relationship at DGIdb | |||
Expression of PRR15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRR15 | 222171 | 226961_at | 0.5410 | 0.4855 | |
| GSE26886 | PRR15 | 222171 | 226961_at | 1.0039 | 0.0008 | |
| GSE45670 | PRR15 | 222171 | 226961_at | 0.1591 | 0.6510 | |
| GSE53622 | PRR15 | 222171 | 70751 | -0.0280 | 0.6212 | |
| GSE53624 | PRR15 | 222171 | 70751 | 0.0823 | 0.1683 | |
| GSE63941 | PRR15 | 222171 | 226961_at | 2.9429 | 0.0129 | |
| GSE77861 | PRR15 | 222171 | 226961_at | 0.3674 | 0.0946 | |
| GSE97050 | PRR15 | 222171 | A_23_P431346 | -0.0244 | 0.9164 | |
| SRP007169 | PRR15 | 222171 | RNAseq | 2.6502 | 0.0049 | |
| SRP133303 | PRR15 | 222171 | RNAseq | 2.3966 | 0.0005 | |
| SRP159526 | PRR15 | 222171 | RNAseq | 3.0414 | 0.0000 | |
| TCGA | PRR15 | 222171 | RNAseq | -0.5496 | 0.0929 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by PRR15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRR15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRR15 | 222171 | 16 | 0 | 14 | |
| GSE20123 | PRR15 | 222171 | 16 | 0 | 14 | |
| GSE43470 | PRR15 | 222171 | 4 | 0 | 39 | |
| GSE46452 | PRR15 | 222171 | 11 | 1 | 47 | |
| GSE47630 | PRR15 | 222171 | 8 | 1 | 31 | |
| GSE54993 | PRR15 | 222171 | 0 | 6 | 64 | |
| GSE54994 | PRR15 | 222171 | 19 | 3 | 31 | |
| GSE60625 | PRR15 | 222171 | 0 | 0 | 11 | |
| GSE74703 | PRR15 | 222171 | 4 | 0 | 32 | |
| GSE74704 | PRR15 | 222171 | 10 | 0 | 10 | |
| TCGA | PRR15 | 222171 | 55 | 6 | 35 |
Total number of gains: 143; Total number of losses: 17; Total Number of normals: 328.
Somatic mutations of PRR15:
Generating mutation plots.
Highly correlated genes for PRR15:
Showing top 20/185 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRR15 | ZSWIM3 | 0.789638 | 3 | 0 | 3 |
| PRR15 | DDX49 | 0.783273 | 4 | 0 | 4 |
| PRR15 | AXIN1 | 0.774642 | 3 | 0 | 3 |
| PRR15 | SLC2A8 | 0.770368 | 3 | 0 | 3 |
| PRR15 | TNNI2 | 0.762792 | 3 | 0 | 3 |
| PRR15 | LAMTOR4 | 0.762152 | 3 | 0 | 3 |
| PRR15 | WRAP73 | 0.760724 | 3 | 0 | 3 |
| PRR15 | DPM3 | 0.759454 | 4 | 0 | 4 |
| PRR15 | TP53BP1 | 0.75678 | 4 | 0 | 4 |
| PRR15 | FAM24B | 0.754621 | 3 | 0 | 3 |
| PRR15 | ZNF511 | 0.748191 | 4 | 0 | 4 |
| PRR15 | RASSF7 | 0.747646 | 3 | 0 | 3 |
| PRR15 | TFB1M | 0.747119 | 3 | 0 | 3 |
| PRR15 | SNORA71A | 0.743078 | 3 | 0 | 3 |
| PRR15 | CHGB | 0.738879 | 3 | 0 | 3 |
| PRR15 | DACH1 | 0.738795 | 3 | 0 | 3 |
| PRR15 | C19orf53 | 0.733433 | 5 | 0 | 4 |
| PRR15 | GARNL3 | 0.732989 | 3 | 0 | 3 |
| PRR15 | ZNF639 | 0.730592 | 3 | 0 | 3 |
| PRR15 | DCPS | 0.723054 | 3 | 0 | 3 |
For details and further investigation, click here
