| Full name: decapping enzyme, scavenger | Alias Symbol: HSPC015|HINT-5|HSL1|HINT5 | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 28960 | HGNC ID: HGNC:29812 | Ensembl Gene: ENSG00000110063 | OMIM ID: 610534 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DCPS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DCPS | 28960 | 218774_at | 0.3432 | 0.1138 | |
| GSE20347 | DCPS | 28960 | 218774_at | 0.1971 | 0.2078 | |
| GSE23400 | DCPS | 28960 | 218774_at | 0.1497 | 0.0280 | |
| GSE26886 | DCPS | 28960 | 218774_at | 0.0260 | 0.9288 | |
| GSE29001 | DCPS | 28960 | 218774_at | 0.4140 | 0.1908 | |
| GSE38129 | DCPS | 28960 | 218774_at | 0.2339 | 0.1000 | |
| GSE45670 | DCPS | 28960 | 218774_at | 0.1472 | 0.4528 | |
| GSE53622 | DCPS | 28960 | 94264 | 0.1194 | 0.1382 | |
| GSE53624 | DCPS | 28960 | 94264 | 0.2921 | 0.0000 | |
| GSE63941 | DCPS | 28960 | 218774_at | 0.2651 | 0.5738 | |
| GSE77861 | DCPS | 28960 | 218774_at | 0.0846 | 0.7853 | |
| GSE97050 | DCPS | 28960 | A_23_P52738 | 0.0699 | 0.7906 | |
| SRP007169 | DCPS | 28960 | RNAseq | -0.2929 | 0.4557 | |
| SRP008496 | DCPS | 28960 | RNAseq | 0.0482 | 0.8525 | |
| SRP064894 | DCPS | 28960 | RNAseq | 0.5153 | 0.0172 | |
| SRP133303 | DCPS | 28960 | RNAseq | 0.0622 | 0.5543 | |
| SRP159526 | DCPS | 28960 | RNAseq | 0.4732 | 0.1915 | |
| SRP193095 | DCPS | 28960 | RNAseq | 0.0462 | 0.6823 | |
| SRP219564 | DCPS | 28960 | RNAseq | 0.2706 | 0.4726 | |
| TCGA | DCPS | 28960 | RNAseq | 0.2196 | 0.0214 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DCPS expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DCPS:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DCPS | 28960 | 0 | 13 | 17 | |
| GSE20123 | DCPS | 28960 | 0 | 13 | 17 | |
| GSE43470 | DCPS | 28960 | 2 | 7 | 34 | |
| GSE46452 | DCPS | 28960 | 3 | 26 | 30 | |
| GSE47630 | DCPS | 28960 | 2 | 19 | 19 | |
| GSE54993 | DCPS | 28960 | 10 | 0 | 60 | |
| GSE54994 | DCPS | 28960 | 5 | 19 | 29 | |
| GSE60625 | DCPS | 28960 | 0 | 3 | 8 | |
| GSE74703 | DCPS | 28960 | 1 | 5 | 30 | |
| GSE74704 | DCPS | 28960 | 0 | 9 | 11 | |
| TCGA | DCPS | 28960 | 7 | 50 | 39 |
Total number of gains: 30; Total number of losses: 164; Total Number of normals: 294.
Somatic mutations of DCPS:
Generating mutation plots.
Highly correlated genes for DCPS:
Showing top 20/139 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DCPS | METTL2B | 0.785398 | 3 | 0 | 3 |
| DCPS | MIIP | 0.761153 | 3 | 0 | 3 |
| DCPS | HSPBAP1 | 0.733148 | 3 | 0 | 3 |
| DCPS | PRR15 | 0.723054 | 3 | 0 | 3 |
| DCPS | CDK12 | 0.722194 | 3 | 0 | 3 |
| DCPS | ATF7IP2 | 0.72194 | 3 | 0 | 3 |
| DCPS | DFFB | 0.721623 | 3 | 0 | 3 |
| DCPS | ZSCAN5A | 0.693723 | 4 | 0 | 3 |
| DCPS | TRDMT1 | 0.685172 | 3 | 0 | 3 |
| DCPS | ARHGAP23 | 0.670667 | 3 | 0 | 3 |
| DCPS | BAX | 0.669575 | 6 | 0 | 4 |
| DCPS | HAPLN3 | 0.6682 | 3 | 0 | 3 |
| DCPS | YEATS2 | 0.657761 | 4 | 0 | 3 |
| DCPS | SMG7 | 0.65265 | 4 | 0 | 3 |
| DCPS | ZNF687 | 0.652036 | 4 | 0 | 3 |
| DCPS | SURF2 | 0.651097 | 4 | 0 | 4 |
| DCPS | TMX2 | 0.642119 | 6 | 0 | 4 |
| DCPS | AXIN1 | 0.637694 | 5 | 0 | 3 |
| DCPS | TOE1 | 0.633934 | 4 | 0 | 3 |
| DCPS | MED20 | 0.628195 | 5 | 0 | 4 |
For details and further investigation, click here
