| Full name: GTPase activating Rap/RanGAP domain like 3 | Alias Symbol: DKFZp761J1523|bA356B19.1 | ||
| Type: protein-coding gene | Cytoband: 9q33.3 | ||
| Entrez ID: 84253 | HGNC ID: HGNC:25425 | Ensembl Gene: ENSG00000136895 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of GARNL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GARNL3 | 84253 | 223604_at | -0.5032 | 0.2230 | |
| GSE26886 | GARNL3 | 84253 | 223604_at | 0.4401 | 0.0246 | |
| GSE45670 | GARNL3 | 84253 | 223604_at | -0.5755 | 0.0002 | |
| GSE53622 | GARNL3 | 84253 | 90840 | -0.1255 | 0.0114 | |
| GSE53624 | GARNL3 | 84253 | 90840 | -0.1093 | 0.0128 | |
| GSE63941 | GARNL3 | 84253 | 223604_at | 0.2301 | 0.4565 | |
| GSE77861 | GARNL3 | 84253 | 223604_at | 0.0102 | 0.9487 | |
| GSE97050 | GARNL3 | 84253 | A_33_P3367491 | -0.1144 | 0.6310 | |
| SRP007169 | GARNL3 | 84253 | RNAseq | 0.6529 | 0.3898 | |
| SRP064894 | GARNL3 | 84253 | RNAseq | -0.8508 | 0.0000 | |
| SRP133303 | GARNL3 | 84253 | RNAseq | -1.0105 | 0.0000 | |
| SRP159526 | GARNL3 | 84253 | RNAseq | -0.8256 | 0.0435 | |
| SRP193095 | GARNL3 | 84253 | RNAseq | -0.1887 | 0.2952 | |
| SRP219564 | GARNL3 | 84253 | RNAseq | -0.7910 | 0.0989 | |
| TCGA | GARNL3 | 84253 | RNAseq | -0.6433 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GARNL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GARNL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GARNL3 | 84253 | 6 | 9 | 15 | |
| GSE20123 | GARNL3 | 84253 | 6 | 9 | 15 | |
| GSE43470 | GARNL3 | 84253 | 5 | 6 | 32 | |
| GSE46452 | GARNL3 | 84253 | 6 | 13 | 40 | |
| GSE47630 | GARNL3 | 84253 | 3 | 16 | 21 | |
| GSE54993 | GARNL3 | 84253 | 3 | 3 | 64 | |
| GSE54994 | GARNL3 | 84253 | 12 | 8 | 33 | |
| GSE60625 | GARNL3 | 84253 | 0 | 0 | 11 | |
| GSE74703 | GARNL3 | 84253 | 5 | 4 | 27 | |
| GSE74704 | GARNL3 | 84253 | 3 | 7 | 10 | |
| TCGA | GARNL3 | 84253 | 27 | 25 | 44 |
Total number of gains: 76; Total number of losses: 100; Total Number of normals: 312.
Somatic mutations of GARNL3:
Generating mutation plots.
Highly correlated genes for GARNL3:
Showing top 20/69 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GARNL3 | POU3F3 | 0.747365 | 3 | 0 | 3 |
| GARNL3 | PRR15 | 0.732989 | 3 | 0 | 3 |
| GARNL3 | PPP1R12B | 0.722108 | 3 | 0 | 3 |
| GARNL3 | BHLHA9 | 0.710214 | 3 | 0 | 3 |
| GARNL3 | SPRY3 | 0.699866 | 3 | 0 | 3 |
| GARNL3 | DMGDH | 0.688768 | 4 | 0 | 3 |
| GARNL3 | GRIK3 | 0.686851 | 3 | 0 | 3 |
| GARNL3 | HSF4 | 0.683194 | 3 | 0 | 3 |
| GARNL3 | LGR6 | 0.674077 | 3 | 0 | 3 |
| GARNL3 | DYRK1B | 0.671214 | 3 | 0 | 3 |
| GARNL3 | UBXN2B | 0.663559 | 3 | 0 | 3 |
| GARNL3 | ZBTB45 | 0.649193 | 3 | 0 | 3 |
| GARNL3 | PRDM6 | 0.648911 | 4 | 0 | 3 |
| GARNL3 | NRK | 0.647361 | 4 | 0 | 4 |
| GARNL3 | CYBRD1 | 0.633971 | 4 | 0 | 4 |
| GARNL3 | C8G | 0.632828 | 4 | 0 | 3 |
| GARNL3 | PRRT2 | 0.628566 | 3 | 0 | 3 |
| GARNL3 | ZC3H6 | 0.623654 | 4 | 0 | 3 |
| GARNL3 | ZNF527 | 0.623534 | 4 | 0 | 3 |
| GARNL3 | VAMP4 | 0.622542 | 5 | 0 | 3 |
For details and further investigation, click here
