| Full name: dolichyl-phosphate mannosyltransferase subunit 3, regulatory | Alias Symbol: MGC34275|MGC125904|MGC125905 | ||
| Type: protein-coding gene | Cytoband: 1q22 | ||
| Entrez ID: 54344 | HGNC ID: HGNC:3007 | Ensembl Gene: ENSG00000179085 | OMIM ID: 605951 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of DPM3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DPM3 | 54344 | 219373_at | 0.5288 | 0.3700 | |
| GSE20347 | DPM3 | 54344 | 219373_at | 0.0540 | 0.7390 | |
| GSE23400 | DPM3 | 54344 | 219373_at | 0.1918 | 0.0570 | |
| GSE26886 | DPM3 | 54344 | 219373_at | 1.3871 | 0.0000 | |
| GSE29001 | DPM3 | 54344 | 219373_at | 0.2966 | 0.3608 | |
| GSE38129 | DPM3 | 54344 | 219373_at | 0.0152 | 0.9382 | |
| GSE45670 | DPM3 | 54344 | 219373_at | 0.0146 | 0.9365 | |
| GSE53622 | DPM3 | 54344 | 59517 | 0.0988 | 0.1662 | |
| GSE53624 | DPM3 | 54344 | 59517 | 0.4154 | 0.0000 | |
| GSE63941 | DPM3 | 54344 | 219373_at | -0.6060 | 0.4991 | |
| GSE77861 | DPM3 | 54344 | 219373_at | 0.3684 | 0.2890 | |
| GSE97050 | DPM3 | 54344 | A_23_P72840 | 0.0318 | 0.9015 | |
| SRP007169 | DPM3 | 54344 | RNAseq | -0.1447 | 0.7645 | |
| SRP008496 | DPM3 | 54344 | RNAseq | 0.3751 | 0.2734 | |
| SRP064894 | DPM3 | 54344 | RNAseq | 0.0390 | 0.9294 | |
| SRP133303 | DPM3 | 54344 | RNAseq | 0.1212 | 0.4975 | |
| SRP159526 | DPM3 | 54344 | RNAseq | 0.6441 | 0.0173 | |
| SRP193095 | DPM3 | 54344 | RNAseq | 0.1410 | 0.4230 | |
| SRP219564 | DPM3 | 54344 | RNAseq | -0.1113 | 0.7986 | |
| TCGA | DPM3 | 54344 | RNAseq | -0.0335 | 0.7281 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DPM3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DPM3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DPM3 | 54344 | 14 | 0 | 16 | |
| GSE20123 | DPM3 | 54344 | 13 | 0 | 17 | |
| GSE43470 | DPM3 | 54344 | 6 | 2 | 35 | |
| GSE46452 | DPM3 | 54344 | 2 | 1 | 56 | |
| GSE47630 | DPM3 | 54344 | 14 | 0 | 26 | |
| GSE54993 | DPM3 | 54344 | 0 | 4 | 66 | |
| GSE54994 | DPM3 | 54344 | 16 | 0 | 37 | |
| GSE60625 | DPM3 | 54344 | 0 | 0 | 11 | |
| GSE74703 | DPM3 | 54344 | 6 | 1 | 29 | |
| GSE74704 | DPM3 | 54344 | 6 | 0 | 14 | |
| TCGA | DPM3 | 54344 | 38 | 2 | 56 |
Total number of gains: 115; Total number of losses: 10; Total Number of normals: 363.
Somatic mutations of DPM3:
Generating mutation plots.
Highly correlated genes for DPM3:
Showing top 20/244 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DPM3 | ZNF777 | 0.777506 | 3 | 0 | 3 |
| DPM3 | LAMA3 | 0.774681 | 3 | 0 | 3 |
| DPM3 | DFFB | 0.767443 | 3 | 0 | 3 |
| DPM3 | CORT | 0.759672 | 3 | 0 | 3 |
| DPM3 | PRR15 | 0.759454 | 4 | 0 | 4 |
| DPM3 | VAV2 | 0.751223 | 3 | 0 | 3 |
| DPM3 | SNAI2 | 0.726919 | 3 | 0 | 3 |
| DPM3 | ZNF687 | 0.721782 | 3 | 0 | 3 |
| DPM3 | ERI1 | 0.721778 | 3 | 0 | 3 |
| DPM3 | GNB1L | 0.712095 | 4 | 0 | 3 |
| DPM3 | APTX | 0.706142 | 4 | 0 | 3 |
| DPM3 | MYO10 | 0.701916 | 3 | 0 | 3 |
| DPM3 | LRR1 | 0.699776 | 3 | 0 | 3 |
| DPM3 | ZMYND15 | 0.696821 | 4 | 0 | 3 |
| DPM3 | FBLN7 | 0.695451 | 3 | 0 | 3 |
| DPM3 | SCUBE1 | 0.694112 | 3 | 0 | 3 |
| DPM3 | SLC45A3 | 0.689066 | 3 | 0 | 3 |
| DPM3 | HAPLN3 | 0.688947 | 3 | 0 | 3 |
| DPM3 | TMEM120B | 0.688917 | 5 | 0 | 4 |
| DPM3 | ZNF620 | 0.688916 | 3 | 0 | 3 |
For details and further investigation, click here
