| Full name: pleckstrin and Sec7 domain containing 3 | Alias Symbol: KIAA0942|HCA67|EFA6R|DKFZp761K1423|EFA6D | ||
| Type: protein-coding gene | Cytoband: 8p22 | ||
| Entrez ID: 23362 | HGNC ID: HGNC:19093 | Ensembl Gene: ENSG00000156011 | OMIM ID: 614440 |
| Drug and gene relationship at DGIdb | |||
Expression of PSD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSD3 | 23362 | 203355_s_at | 0.6767 | 0.3504 | |
| GSE20347 | PSD3 | 23362 | 203354_s_at | -0.1963 | 0.5496 | |
| GSE23400 | PSD3 | 23362 | 218613_at | 0.2080 | 0.0849 | |
| GSE26886 | PSD3 | 23362 | 203355_s_at | 0.1103 | 0.7721 | |
| GSE29001 | PSD3 | 23362 | 203355_s_at | -0.8007 | 0.1469 | |
| GSE38129 | PSD3 | 23362 | 203355_s_at | -0.0625 | 0.8059 | |
| GSE45670 | PSD3 | 23362 | 203355_s_at | -0.1972 | 0.6694 | |
| GSE53622 | PSD3 | 23362 | 55392 | -0.2565 | 0.0812 | |
| GSE53624 | PSD3 | 23362 | 55392 | -0.4215 | 0.0002 | |
| GSE63941 | PSD3 | 23362 | 203355_s_at | -3.4231 | 0.0003 | |
| GSE77861 | PSD3 | 23362 | 218613_at | 0.1927 | 0.5729 | |
| GSE97050 | PSD3 | 23362 | A_24_P18146 | -0.0545 | 0.8913 | |
| SRP007169 | PSD3 | 23362 | RNAseq | -0.1255 | 0.7497 | |
| SRP008496 | PSD3 | 23362 | RNAseq | -0.1608 | 0.4740 | |
| SRP064894 | PSD3 | 23362 | RNAseq | -0.5132 | 0.0752 | |
| SRP133303 | PSD3 | 23362 | RNAseq | -0.2149 | 0.2740 | |
| SRP159526 | PSD3 | 23362 | RNAseq | -0.1925 | 0.5368 | |
| SRP193095 | PSD3 | 23362 | RNAseq | -0.3532 | 0.0243 | |
| SRP219564 | PSD3 | 23362 | RNAseq | -0.6010 | 0.2816 | |
| TCGA | PSD3 | 23362 | RNAseq | -0.2135 | 0.0435 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PSD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSD3 | 23362 | 4 | 10 | 16 | |
| GSE20123 | PSD3 | 23362 | 4 | 10 | 16 | |
| GSE43470 | PSD3 | 23362 | 4 | 8 | 31 | |
| GSE46452 | PSD3 | 23362 | 14 | 13 | 32 | |
| GSE47630 | PSD3 | 23362 | 10 | 8 | 22 | |
| GSE54993 | PSD3 | 23362 | 2 | 14 | 54 | |
| GSE54994 | PSD3 | 23362 | 8 | 18 | 27 | |
| GSE60625 | PSD3 | 23362 | 3 | 0 | 8 | |
| GSE74703 | PSD3 | 23362 | 4 | 7 | 25 | |
| GSE74704 | PSD3 | 23362 | 3 | 7 | 10 | |
| TCGA | PSD3 | 23362 | 13 | 43 | 40 |
Total number of gains: 69; Total number of losses: 138; Total Number of normals: 281.
Somatic mutations of PSD3:
Generating mutation plots.
Highly correlated genes for PSD3:
Showing top 20/153 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSD3 | VCPIP1 | 0.774997 | 3 | 0 | 3 |
| PSD3 | SH3PXD2A | 0.721037 | 3 | 0 | 3 |
| PSD3 | SUFU | 0.719244 | 3 | 0 | 3 |
| PSD3 | ELMOD2 | 0.70912 | 3 | 0 | 3 |
| PSD3 | PIGB | 0.700838 | 3 | 0 | 3 |
| PSD3 | HSD17B10 | 0.697289 | 3 | 0 | 3 |
| PSD3 | GRB2 | 0.694503 | 3 | 0 | 3 |
| PSD3 | ZHX2 | 0.692985 | 3 | 0 | 3 |
| PSD3 | MAGED1 | 0.689417 | 3 | 0 | 3 |
| PSD3 | GBGT1 | 0.688618 | 3 | 0 | 3 |
| PSD3 | ADO | 0.682894 | 3 | 0 | 3 |
| PSD3 | TULP4 | 0.680477 | 3 | 0 | 3 |
| PSD3 | FUCA1 | 0.667876 | 3 | 0 | 3 |
| PSD3 | TTC39C | 0.665197 | 3 | 0 | 3 |
| PSD3 | MTMR12 | 0.659542 | 3 | 0 | 3 |
| PSD3 | NAA40 | 0.658417 | 3 | 0 | 3 |
| PSD3 | CEP44 | 0.656324 | 4 | 0 | 3 |
| PSD3 | ZBED4 | 0.65518 | 4 | 0 | 3 |
| PSD3 | SLC39A6 | 0.652362 | 3 | 0 | 3 |
| PSD3 | ABCC4 | 0.652044 | 4 | 0 | 3 |
For details and further investigation, click here
