| Full name: zinc fingers and homeoboxes 2 | Alias Symbol: KIAA0854 | ||
| Type: protein-coding gene | Cytoband: 8q24.13 | ||
| Entrez ID: 22882 | HGNC ID: HGNC:18513 | Ensembl Gene: ENSG00000178764 | OMIM ID: 609185 |
| Drug and gene relationship at DGIdb | |||
Expression of ZHX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZHX2 | 22882 | 203556_at | 0.2457 | 0.5794 | |
| GSE20347 | ZHX2 | 22882 | 203556_at | 0.7817 | 0.0053 | |
| GSE23400 | ZHX2 | 22882 | 203556_at | 0.4198 | 0.0001 | |
| GSE26886 | ZHX2 | 22882 | 203556_at | 1.1505 | 0.0000 | |
| GSE29001 | ZHX2 | 22882 | 203556_at | 0.4485 | 0.1380 | |
| GSE38129 | ZHX2 | 22882 | 203556_at | 0.3876 | 0.0438 | |
| GSE45670 | ZHX2 | 22882 | 203556_at | -0.2644 | 0.3521 | |
| GSE53622 | ZHX2 | 22882 | 74629 | 0.2397 | 0.0072 | |
| GSE53624 | ZHX2 | 22882 | 74629 | 0.3336 | 0.0001 | |
| GSE63941 | ZHX2 | 22882 | 203556_at | -0.0196 | 0.9877 | |
| GSE77861 | ZHX2 | 22882 | 203556_at | 0.5721 | 0.1348 | |
| GSE97050 | ZHX2 | 22882 | A_23_P168951 | 0.0087 | 0.9774 | |
| SRP007169 | ZHX2 | 22882 | RNAseq | 1.6805 | 0.0015 | |
| SRP008496 | ZHX2 | 22882 | RNAseq | 1.3554 | 0.0007 | |
| SRP064894 | ZHX2 | 22882 | RNAseq | 0.0211 | 0.8925 | |
| SRP133303 | ZHX2 | 22882 | RNAseq | -0.1238 | 0.6319 | |
| SRP159526 | ZHX2 | 22882 | RNAseq | 0.3310 | 0.3314 | |
| SRP193095 | ZHX2 | 22882 | RNAseq | 0.5424 | 0.0005 | |
| SRP219564 | ZHX2 | 22882 | RNAseq | 0.3900 | 0.4245 | |
| TCGA | ZHX2 | 22882 | RNAseq | 0.0800 | 0.2487 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by ZHX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZHX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZHX2 | 22882 | 19 | 1 | 10 | |
| GSE20123 | ZHX2 | 22882 | 20 | 1 | 9 | |
| GSE43470 | ZHX2 | 22882 | 22 | 0 | 21 | |
| GSE46452 | ZHX2 | 22882 | 27 | 0 | 32 | |
| GSE47630 | ZHX2 | 22882 | 24 | 0 | 16 | |
| GSE54993 | ZHX2 | 22882 | 0 | 21 | 49 | |
| GSE54994 | ZHX2 | 22882 | 37 | 1 | 15 | |
| GSE60625 | ZHX2 | 22882 | 0 | 4 | 7 | |
| GSE74703 | ZHX2 | 22882 | 19 | 0 | 17 | |
| GSE74704 | ZHX2 | 22882 | 13 | 1 | 6 | |
| TCGA | ZHX2 | 22882 | 67 | 2 | 27 |
Total number of gains: 248; Total number of losses: 31; Total Number of normals: 209.
Somatic mutations of ZHX2:
Generating mutation plots.
Highly correlated genes for ZHX2:
Showing top 20/843 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZHX2 | DDB1 | 0.818945 | 3 | 0 | 3 |
| ZHX2 | TTC7B | 0.800708 | 3 | 0 | 3 |
| ZHX2 | DNAH14 | 0.783394 | 3 | 0 | 3 |
| ZHX2 | THEM4 | 0.776541 | 3 | 0 | 3 |
| ZHX2 | PIK3R3 | 0.774925 | 3 | 0 | 3 |
| ZHX2 | HABP4 | 0.773473 | 3 | 0 | 3 |
| ZHX2 | TMED8 | 0.770805 | 3 | 0 | 3 |
| ZHX2 | TRPM7 | 0.765889 | 3 | 0 | 3 |
| ZHX2 | CRKL | 0.765059 | 3 | 0 | 3 |
| ZHX2 | SLC39A13 | 0.764128 | 3 | 0 | 3 |
| ZHX2 | FLOT2 | 0.761398 | 3 | 0 | 3 |
| ZHX2 | CDKN1C | 0.758589 | 3 | 0 | 3 |
| ZHX2 | KLHL7 | 0.757595 | 3 | 0 | 3 |
| ZHX2 | MSTO1 | 0.755546 | 3 | 0 | 3 |
| ZHX2 | PSMC4 | 0.755324 | 3 | 0 | 3 |
| ZHX2 | TIGD1 | 0.753679 | 3 | 0 | 3 |
| ZHX2 | GPR107 | 0.753573 | 3 | 0 | 3 |
| ZHX2 | C1orf43 | 0.751335 | 3 | 0 | 3 |
| ZHX2 | MAP3K13 | 0.749562 | 3 | 0 | 3 |
| ZHX2 | SEC22C | 0.737673 | 3 | 0 | 3 |
For details and further investigation, click here
