| Full name: valosin containing protein interacting protein 1 | Alias Symbol: VCIP135|KIAA1850|FLJ23132|DUBA3 | ||
| Type: protein-coding gene | Cytoband: 8q13.1 | ||
| Entrez ID: 80124 | HGNC ID: HGNC:30897 | Ensembl Gene: ENSG00000175073 | OMIM ID: 611745 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of VCPIP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VCPIP1 | 80124 | 1556228_a_at | 0.2427 | 0.6545 | |
| GSE20347 | VCPIP1 | 80124 | 219810_at | 0.0833 | 0.2962 | |
| GSE23400 | VCPIP1 | 80124 | 219810_at | 0.0676 | 0.0205 | |
| GSE26886 | VCPIP1 | 80124 | 1556228_a_at | -0.6371 | 0.1477 | |
| GSE29001 | VCPIP1 | 80124 | 219810_at | 0.3898 | 0.1118 | |
| GSE38129 | VCPIP1 | 80124 | 219810_at | 0.0883 | 0.2114 | |
| GSE45670 | VCPIP1 | 80124 | 1556228_a_at | -0.1874 | 0.2372 | |
| GSE53622 | VCPIP1 | 80124 | 76871 | -0.0720 | 0.2468 | |
| GSE53624 | VCPIP1 | 80124 | 76871 | 0.0430 | 0.4737 | |
| GSE63941 | VCPIP1 | 80124 | 1556228_a_at | -1.3489 | 0.0069 | |
| GSE77861 | VCPIP1 | 80124 | 219810_at | -0.1618 | 0.2978 | |
| GSE97050 | VCPIP1 | 80124 | A_33_P3223467 | -0.0491 | 0.8494 | |
| SRP007169 | VCPIP1 | 80124 | RNAseq | 0.8181 | 0.0149 | |
| SRP008496 | VCPIP1 | 80124 | RNAseq | 0.9099 | 0.0001 | |
| SRP064894 | VCPIP1 | 80124 | RNAseq | 0.4920 | 0.0102 | |
| SRP133303 | VCPIP1 | 80124 | RNAseq | 0.3114 | 0.0146 | |
| SRP159526 | VCPIP1 | 80124 | RNAseq | -0.2911 | 0.1530 | |
| SRP193095 | VCPIP1 | 80124 | RNAseq | 0.0717 | 0.2993 | |
| SRP219564 | VCPIP1 | 80124 | RNAseq | 0.3263 | 0.2238 | |
| TCGA | VCPIP1 | 80124 | RNAseq | -0.0004 | 0.9939 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by VCPIP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VCPIP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VCPIP1 | 80124 | 14 | 1 | 15 | |
| GSE20123 | VCPIP1 | 80124 | 15 | 1 | 14 | |
| GSE43470 | VCPIP1 | 80124 | 15 | 3 | 25 | |
| GSE46452 | VCPIP1 | 80124 | 20 | 2 | 37 | |
| GSE47630 | VCPIP1 | 80124 | 23 | 1 | 16 | |
| GSE54993 | VCPIP1 | 80124 | 1 | 18 | 51 | |
| GSE54994 | VCPIP1 | 80124 | 30 | 0 | 23 | |
| GSE60625 | VCPIP1 | 80124 | 0 | 4 | 7 | |
| GSE74703 | VCPIP1 | 80124 | 13 | 2 | 21 | |
| GSE74704 | VCPIP1 | 80124 | 10 | 0 | 10 | |
| TCGA | VCPIP1 | 80124 | 49 | 4 | 43 |
Total number of gains: 190; Total number of losses: 36; Total Number of normals: 262.
Somatic mutations of VCPIP1:
Generating mutation plots.
Highly correlated genes for VCPIP1:
Showing top 20/325 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VCPIP1 | USP38 | 0.854914 | 3 | 0 | 3 |
| VCPIP1 | PSD3 | 0.774997 | 3 | 0 | 3 |
| VCPIP1 | FBXL3 | 0.76119 | 3 | 0 | 3 |
| VCPIP1 | TLR3 | 0.755613 | 3 | 0 | 3 |
| VCPIP1 | PALB2 | 0.752433 | 3 | 0 | 3 |
| VCPIP1 | PPP1R3D | 0.745465 | 3 | 0 | 3 |
| VCPIP1 | NAA20 | 0.738708 | 3 | 0 | 3 |
| VCPIP1 | ZMYM2 | 0.737663 | 3 | 0 | 3 |
| VCPIP1 | UFL1 | 0.73632 | 3 | 0 | 3 |
| VCPIP1 | TET2 | 0.725015 | 4 | 0 | 3 |
| VCPIP1 | FAM200A | 0.724945 | 3 | 0 | 3 |
| VCPIP1 | ATL1 | 0.724885 | 3 | 0 | 3 |
| VCPIP1 | PI4K2A | 0.721878 | 3 | 0 | 3 |
| VCPIP1 | RNASEL | 0.721779 | 4 | 0 | 3 |
| VCPIP1 | GTF2E2 | 0.720095 | 3 | 0 | 3 |
| VCPIP1 | CLOCK | 0.717474 | 3 | 0 | 3 |
| VCPIP1 | TRIM13 | 0.716092 | 3 | 0 | 3 |
| VCPIP1 | HGF | 0.715183 | 3 | 0 | 3 |
| VCPIP1 | SLC25A3 | 0.71382 | 3 | 0 | 3 |
| VCPIP1 | ARFGEF2 | 0.713567 | 4 | 0 | 4 |
For details and further investigation, click here
